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Akhilesh Kotiyal
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Unlocking the potential of TRPV1 based siRNA therapeutics for the treatment of chemotherapy-induced neuropathic pain
Akhilesh, A Uniyal, A Gadepalli, V Tiwari, M Allani, D Chouhan, ...
Life Sciences, 120187, 2021
28*2021
Underpinning the neurobiological intricacies associated with opioid tolerance
A Uniyal, A Gadepalli, Akhilesh, V Tiwari
ACS chemical neuroscience 11 (6), 830-839, 2020
162020
Inhibition of pan-Aurora kinase attenuates evoked and ongoing pain in nerve injured rats via regulating KIF17-NR2B mediated signaling
A Uniyal, Akhilesh, AS Rathore, PK Keshri, SP Singh, S Singh, V Tiwari
International Immunopharmacology 106, 108622, 2022
152022
Multifarious targets and recent developments in the therapeutics for the management of bone cancer pain
A Gadepalli, Akhilesh, A Uniyal, A Modi, D Chouhan, O Ummadisetty, ...
ACS Chemical Neuroscience 12 (22), 4195-4208, 2021
142021
Epigallocatechin-3-gallate improves chronic alcohol-induced cognitive dysfunction in rats by interfering with neuro-inflammatory, cell death and oxido-nitrosative cascade
A Uniyal, Akhilesh, V Tiwari, A Gadepalli, O Ummadisetty, V Tiwari
Metabolic Brain Disease 36 (7), 2141-2153, 2021
142021
Design, Synthesis, and Biological Evaluation of Piperazine and N-Benzylpiperidine Hybrids of 5-Phenyl-1,3,4-oxadiazol-2-thiol as Potential Multitargeted Ligands …
DK Waiker, A Verma, Akhilesh, N Singh, A Roy, H Dilnashin, V Tiwari, ...
ACS Chemical Neuroscience 14 (11), 2217-2242, 2023
102023
Kinesin nanomotors mediated trafficking of NMDA-Loaded cargo as a novel target in chronic pain
A Uniyal, V Thakur, M Rani, V Tiwari, Akhilesh, A Gadepalli, ...
ACS Chemical Neuroscience 12 (16), 2956-2963, 2021
92021
Structure-based virtual screening and molecular dynamics simulation for the identification of sphingosine kinase-2 inhibitors as potential analgesics
Akhilesh, ATK Baidya, A Uniyal, B Das, R Kumar, V Tiwari
Journal of Biomolecular Structure and Dynamics 40 (23), 12472-12490, 2022
82022
Decrypting the cellular and molecular intricacies associated with COVID-19-induced chronic pain
M Rani, A Uniyal, Akhilesh, V Tiwari
Metabolic Brain Disease, 1-14, 2022
62022
Loperamide, a peripheral Mu-Opioid receptor agonist, attenuates chemotherapy-induced neuropathic pain in rats
A Gadepalli, O Ummadisetty, Akhilesh, D Chouhan, Anmol, V Tiwari
International Immunopharmacology 124, 110944, 2023
42023
Multifactorial pathways in burn injury-induced chronic pain: novel targets and their pharmacological modulation
TK Roy, A Uniyal, Akhilesh, V Tiwari
Molecular Biology Reports, 1-12, 2022
42022
Synthesis and evaluation of dual fatty acid amide hydrolase-monoacylglycerol lipase inhibition and antinociceptive activities of 4-methylsulfonylaniline-derived semicarbazones
S Jaiswal, Akhilesh, A Uniyal, V Tiwari, SR Ayyannan
Bioorganic & Medicinal Chemistry 60, 116698, 2022
42022
Recent advancements in biomarker research in schizophrenia: mapping the road from bench to bedside
S Patel, D Sharma, A Uniyal, Akhilesh, A Gadepalli, V Tiwari
Metabolic Brain Disease, 1-15, 2022
42022
Antiepileptic activity of hydroethanolic extract of Thalictrum foliolosum on maximal electroshock (MES) and pentylenetetrazole (PTZ) induced seizure in rats.
Akhilesh, N.K. and Bisht, M.
International journal of pharmacology & toxicology, 7, 2017
42017
Probing the Manipulated Neurochemical Drive in Alcohol Addiction and Novel Therapeutic Advancements
D Chouhan, A Uniyal, A Gadepalli, Akhilesh, V Tiwari, S Agrawal, TK Roy, ...
ACS chemical neuroscience 11 (9), 1210-1217, 2020
32020
In vitro antioxidant activity of whole plant extracts of Thalictrum foliolosum DC (pilijari)
Akhilesh, A Kumar, N Sharma, D Bisht
Am J PharmTech Res 6, 200-212, 2016
32016
Glucose regulation by newly synthesized boronic acid functionalized molecules as dipeptidyl peptidase IV inhibitor: a potential compound for therapeutic intervention in …
N Prajapati, D Sharma, P Ashok Bidve, Akhilesh, D Chouhan, M Allani, ...
Journal of Biomolecular Structure and Dynamics 42 (6), 2859-2871, 2024
22024
Peripheral mu-opioid receptor activation by dermorphin [D-Arg2, Lys4](1–4) amide alleviates behavioral and neurobiological aberrations in rat model of chemotherapy-induced …
A Gadepalli, O Ummadisetty, Akhilesh, D Chouhan, KE Yadav, V Tiwari
Neurotherapeutics, e00302, 2023
22023
Combination chemotherapy in rodents: a model for chemotherapy-induced neuropathic pain and pharmacological screening
Akhilesh, A Uniyal, A Mehta, V Tiwari
Metabolic Brain Disease, 1-23, 2023
22023
Disentangling the enigmatic role of ephrin signaling in chronic pain: Moving towards future anti-pain therapeutics
A Modi, P Pandey, A Akhilesh, Uniyal, D Chouhan, S Agrawal, M Allani, ...
Life Sciences, 121796, 2023
22023
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