Configuration of human dendritic cell cytoskeleton by Rho GTPases, the WAS protein, and differentiation S Burns, AJ Thrasher, MP Blundell, L Machesky, GE Jones Blood, The Journal of the American Society of Hematology 98 (4), 1142-1149, 2001 | 400 | 2001 |
Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor γ chain JP Goldman, MP Blundell, L Lopes, C Kinnon, JP DI Santo, AJ Thrasher British journal of haematology 103 (2), 335-342, 1998 | 308 | 1998 |
Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia PJ Ancliff, MP Blundell, GO Cory, Y Calle, A Worth, H Kempski, S Burns, ... Blood 108 (7), 2182-2189, 2006 | 259 | 2006 |
Stable gene transfer to muscle using non-integrating lentiviral vectors L Apolonia, SN Waddington, C Fernandes, NJ Ward, G Bouma, ... Molecular Therapy 15 (11), 1947-1954, 2007 | 234 | 2007 |
Deficiency in the Wiskott-Aldrich protein induces premature proplatelet formation and platelet production in the bone marrow compartment S Sabri, A Foudi, S Boukour, B Franc, S Charrier, M Jandrot-Perrus, ... Blood 108 (1), 134-140, 2006 | 231 | 2006 |
Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia DA Moulding, MP Blundell, DG Spiller, MRH White, GO Cory, Y Calle, ... The Journal of experimental medicine 204 (9), 2213-2224, 2007 | 189 | 2007 |
Valproic acid confers functional pluripotency to human amniotic fluid stem cells in a transgene-free approach D Moschidou, S Mukherjee, MP Blundell, K Drews, GN Jones, ... Molecular Therapy 20 (10), 1953-1967, 2012 | 177 | 2012 |
A ubiquitous chromatin opening element (UCOE) confers resistance to DNA methylation–mediated silencing of lentiviral vectors F Zhang, AR Frost, MP Blundell, O Bales, MN Antoniou, AJ Thrasher Molecular therapy 18 (9), 1640-1649, 2010 | 163 | 2010 |
Biochemical correction of X-CGD by a novel chimeric promoter regulating high levels of transgene expression in myeloid cells G Santilli, E Almarza, C Brendel, U Choi, C Beilin, MP Blundell, S Haria, ... Molecular Therapy 19 (1), 122-132, 2011 | 161 | 2011 |
Cutting edge: the Wiskott-Aldrich syndrome protein is required for efficient phagocytosis of apoptotic cells Y Leverrier, R Lorenzi, MP Blundell, P Brickell, C Kinnon, AJ Ridley, ... The Journal of Immunology 166 (8), 4831-4834, 2001 | 151 | 2001 |
Impaired dendritic-cell homing in vivo in the absence of Wiskott-Aldrich syndrome protein S de Noronha, S Hardy, J Sinclair, MP Blundell, J Strid, O Schulz, ... Blood 105 (4), 1590-1597, 2005 | 149 | 2005 |
The Wiskott-Aldrich syndrome: the actin cytoskeleton and immune cell function MP Blundell, A Worth, G Bouma, AJ Thrasher Disease markers 29 (3-4), 157-175, 2010 | 144 | 2010 |
WASp deficiency in mice results in failure to form osteoclast sealing zones and defects in bone resorption Y Calle, GE Jones, C Jagger, K Fuller, MP Blundell, J Chow, T Chambers, ... Blood 103 (9), 3552-3561, 2004 | 143 | 2004 |
Lentiviral vectors targeting WASp expression to hematopoietic cells, efficiently transduce and correct cells from WAS patients S Charrier, L Dupre, S Scaramuzza, L Jeanson-Leh, MP Blundell, ... Gene therapy 14 (5), 415-428, 2007 | 136 | 2007 |
Autoinflammatory periodic fever, immunodeficiency, and thrombocytopenia (PFIT) caused by mutation in actin-regulatory gene WDR1 ASI Standing, D Malinova, Y Hong, J Record, D Moulding, MP Blundell, ... Journal of Experimental Medicine 214 (1), 59-71, 2017 | 135 | 2017 |
Restoration of podosomes and chemotaxis in Wiskott–Aldrich syndrome macrophages following induced expression of WASp GE Jones, D Zicha, GA Dunn, M Blundell, A Thrasher The international journal of biochemistry & cell biology 34 (7), 806-815, 2002 | 125 | 2002 |
Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane H Schachtner, SDJ Calaminus, A Sinclair, J Monypenny, MP Blundell, ... Blood, The Journal of the American Society of Hematology 121 (13), 2542-2552, 2013 | 122 | 2013 |
Nonintegrating lentivector vaccines stimulate prolonged T-cell and antibody responses and are effective in tumor therapy K Karwacz, S Mukherjee, L Apolonia, MP Blundell, G Bouma, D Escors, ... Journal of Virology 83 (7), 3094-3103, 2009 | 101 | 2009 |
Preclinical demonstration of lentiviral vector-mediated correction of immunological and metabolic abnormalities in models of adenosine deaminase deficiency DA Carbonaro, L Zhang, X Jin, C Montiel-Equihua, S Geiger, M Carmo, ... Molecular Therapy 22 (3), 607-622, 2014 | 97 | 2014 |
Cytoskeletal remodeling mediated by WASp in dendritic cells is necessary for normal immune synapse formation and T-cell priming G Bouma, A Mendoza-Naranjo, MP Blundell, E De Falco, KL Parsley, ... Blood, The Journal of the American Society of Hematology 118 (9), 2492-2501, 2011 | 97 | 2011 |