A bis-Benzylidine Piperidone Targeting Proteasome Ubiquitin Receptor RPN13/ADRM1 as a Therapy for Cancer 1 Ravi K. Anchoori,1 Balasubramanyam Karanam,2 CANCER CELL 24 (6), 791-805, 2013 | 166 | 2013 |
Fenugreek: a naturally occurring edible spice as an anticancer agent S Shabbeer, M Sobolewski, RK Anchoori, S Kachhap, M Hidalgo, ... Cancer biology & therapy 8 (3), 272-278, 2009 | 166 | 2009 |
α, β-Unsaturated carbonyl system of chalcone-based derivatives is responsible for broad inhibition of proteasomal activity and preferential killing of human papilloma virus … M Bazzaro, RK Anchoori, MKR Mudiam, O Issaenko, S Kumar, B Karanam, ... Journal of medicinal chemistry 54 (2), 449-456, 2011 | 115 | 2011 |
Targeted inhibition of hedgehog signaling by cyclopamine prodrugs for advanced prostate cancer SK Kumar, I Roy, RK Anchoori, S Fazli, A Maitra, PA Beachy, SR Khan Bioorganic & medicinal chemistry 16 (6), 2764-2768, 2008 | 85 | 2008 |
The proteasome ubiquitin receptor hRpn13 and its interacting deubiquitinating enzyme Uch37 are required for proper cell cycle progression L Randles, RK Anchoori, RBS Roden, KJ Walters Journal of Biological Chemistry 291 (16), 8773-8783, 2016 | 65 | 2016 |
Small-Molecule RA-9 Inhibits Proteasome-Associated DUBs and Ovarian Cancer In Vitro and In Vivo via Exacerbating Unfolded Protein Responses K Coughlin, R Anchoori, Y Iizuka, J Meints, L MacNeill, RI Vogel, ... Clinical cancer research 20 (12), 3174-3186, 2014 | 64 | 2014 |
Potent genistein derivatives as inhibitors of estrogen receptor alpha-positive breast cancer R Marik, M Allu, R Anchoori, V Stearns, CB Umbricht, S Khan Cancer Biology & Therapy 11 (10), 883-892, 2011 | 63 | 2011 |
Simultaneous inhibition of deubiquitinating enzymes (DUBs) and autophagy synergistically kills breast cancer cells RI Vogel, K Coughlin, A Scotti, Y Iizuka, R Anchoori, RBS Roden, ... Oncotarget 6 (6), 4159, 2015 | 59 | 2015 |
Stressing the ubiquitin-proteasome system without 20S proteolytic inhibition selectively kills cervical cancer cells RK Anchoori, SR Khan, T Sueblinvong, A Felthauser, Y Iizuka, R Gavioli, ... PloS one 6 (8), e23888, 2011 | 52 | 2011 |
Biological evaluation of paclitaxel-peptide conjugates as a model for MMP2-targeted drug delivery R Yamada, MB Kostova, RK Anchoori, S Xu, N Neamati, S Khan Cancer biology & therapy 9 (3), 192-203, 2010 | 43 | 2010 |
Novel microtubule-interacting phenoxy pyridine and phenyl sulfanyl pyridine analogues for cancer therapy RK Anchoori, MSQ Kortenhorst, M Hidalgo, T Sarkar, G Hallur, R Bai, ... Journal of medicinal chemistry 51 (19), 5953-5957, 2008 | 35 | 2008 |
RPN13/ADRM1 inhibitor reverses immunosuppression by myeloid-derived suppressor cells RS Soong, RK Anchoori, B Yang, A Yang, SH Tseng, L He, YC Tsai, ... Oncotarget 7 (42), 68489, 2016 | 33 | 2016 |
Covalent Rpn13-binding inhibitors for the treatment of ovarian cancer RK Anchoori, R Jiang, S Peng, R Soong, A Algethami, MA Rudek, ... ACS omega 3 (9), 11917-11929, 2018 | 32 | 2018 |
ADRM 1‐amplified metastasis gene in gastric cancer MS Fejzo, L Anderson, HW Chen, A Anghel, J Zhuo, R Anchoori, R Roden, ... Genes, Chromosomes and Cancer 54 (8), 506-515, 2015 | 28 | 2015 |
mTORC1 feedback to AKT modulates lysosomal biogenesis through MiT/TFE regulation K Asrani, S Murali, B Lam, CH Na, P Phatak, A Sood, H Kaur, Z Khan, ... The Journal of clinical investigation 129 (12), 5584-5599, 2019 | 25 | 2019 |
Inhibition of IkB kinase and NF-κB by a novel synthetic compound SK 2009 RK Anchoori, KB Harikumar, VR Batchu, BB Aggarwal, SR Khan Bioorganic & medicinal chemistry 18 (1), 229-235, 2010 | 25 | 2010 |
Early and consistent overexpression of ADRM1 in ovarian high-grade serous carcinoma RT Jiang, A Yemelyanova, D Xing, RK Anchoori, J Hamazaki, S Murata, ... Journal of Ovarian Research 10, 1-12, 2017 | 23 | 2017 |
Stereoselective synthesis and biological studies of the C2 and C3 epimer and the enantiomer of Pachastrissamine (Jaspine B) G Jayachitra, N Sudhakar, RK Anchoori, BV Rao, S Roy, R Banerjee Synthesis 2010 (01), 115-119, 2010 | 18 | 2010 |
Bis-benzylidine Piperidone RA190 treatment of hepatocellular carcinoma via binding RPN13 and inhibiting NF-κB signaling RS Soong, RK Anchoori, RBS Roden, RL Cho, YC Chen, SC Tseng, ... BMC cancer 20, 1-15, 2020 | 16 | 2020 |
Rational design of novel antiandrogens for neutralizing androgen receptor function in hormone refractory prostate cancer P Singh, G Hallur, RK Anchoori, O Bakare, Y Kageyama, SR Khan, ... The Prostate 68 (14), 1570-1581, 2008 | 14 | 2008 |