| Structure and ligand based drug design strategies in the development of novel 5-LOX inhibitors P Aparoy, K Kumar Reddy, P Reddanna Current medicinal chemistry 19 (22), 3763-3778, 2012 | 219 | 2012 |
| Evolutionary aspects of lipoxygenases and genetic diversity of human leukotriene signaling T Horn, S Adel, R Schumann, S Sur, KR Kakularam, A Polamarasetty, ... Progress in lipid research 57, 13-39, 2015 | 119 | 2015 |
| Exploration of binding site pattern in arachidonic acid metabolizing enzymes, Cyclooxygenases and Lipoxygenases KK Reddy, VK Vidya Rajan, A Gupta, P Aparoy, P Reddanna BMC research notes 8, 1-10, 2015 | 51 | 2015 |
| Conversion of pro-inflammatory murine Alox5 into an anti-inflammatory 15S-lipoxygenating enzyme by multiple mutations of sequence determinants K Hofheinz, KR Kakularam, S Adel, M Anton, A Polymarasetty, ... Archives of biochemistry and biophysics 530 (1), 40-47, 2013 | 36 | 2013 |
| Functional characterization of genetic enzyme variations in human lipoxygenases T Horn, KR Kakularam, M Anton, C Richter, P Reddanna, H Kuhn Redox biology 1 (1), 566-577, 2013 | 34 | 2013 |
| CoMFA and CoMSIA studies on 5-hydroxyindole-3-carboxylate derivatives as 5-lipoxygenase inhibitors: Generation of homology model and docking studies P Aparoy, GK Suresh, KK Reddy, P Reddanna Bioorganic & medicinal chemistry letters 21 (1), 456-462, 2011 | 28 | 2011 |
| Pharmacophore modeling and virtual screening for designing potential 5-Lipoxygenase inhibitors P Aparoy, KK Reddy, SK Kalangi, TC Reddy, P Reddanna Bioorganic & medicinal chemistry letters 20 (3), 1013-1018, 2010 | 28 | 2010 |
| The augmenting effects of desolvation and conformational energy terms on the predictions of docking programs against mPGES-1 A Gupta, N Chaudhary, KR Kakularam, R Pallu, A Polamarasetty PLoS One 10 (8), e0134472, 2015 | 26 | 2015 |
| Isoorientin, a Selective Inhibitor of Cyclooxygenase-2 (COX-2) from the Tubers of Pueraria tuberosa M Sumalatha, R Munikishore, A Rammohan, D Gunasekar, KA Kumar, ... Natural product communications 10 (10), 1934578X1501001017, 2015 | 21 | 2015 |
| Leukotriene signaling in the extinct human subspecies Homo denisovan and Homo neanderthalensis. Structural and functional comparison with Homo sapiens S Adel, KR Kakularam, T Horn, P Reddanna, H Kuhn, D Heydeck Archives of biochemistry and biophysics 565, 17-24, 2015 | 20 | 2015 |
| Modern Annulation Strategies for the Synthesis of Cyclo [b] fused Indoles E Haak Synlett 30 (03), 245-251, 2019 | 19 | 2019 |
| Studies on the preparation and quality of kulfi. A Ashokraju, MP Ali, KK Reddy, CR Reddy, MR Rao | 14 | 1989 |
| Understanding the dual inhibition of COX-2 and carbonic anhydrase-II by Celecoxib and CG100649 using density functional theory calculations and other molecular modelling approaches O Singh, K R Kakularam, P Reddanna, P Aparoy Protein and Peptide Letters 22 (10), 903-912, 2015 | 12 | 2015 |
| N-Substituted 5-(1H-Indol-2-yl)-2-methoxyanilines Are Allosteric Inhibitors of the Linoleate Oxygenase Activity of Selected Mammalian ALOX15 Orthologs … A Golovanov, A Zhuravlev, A Cruz, V Aksenov, R Shafiullina, ... Journal of medicinal chemistry 65 (3), 1979-1995, 2022 | 11 | 2022 |
| Male knock-in mice expressing an arachidonic acid lipoxygenase 15B (Alox15B) with humanized reaction specificity are prematurely growth arrested when aging M Schäfer, KR Kakularam, F Reisch, M Rothe, S Stehling, D Heydeck, ... Biomedicines 10 (6), 1379, 2022 | 10 | 2022 |
| Thr92Ala polymorphism in the type 2 deiodinase gene: an evolutionary perspective C Ricci, KR Kakularam, C Marzocchi, G Capecchi, G Riolo, F Boschin, ... Journal of Endocrinological Investigation 43, 1749-1757, 2020 | 10 | 2020 |
| The reaction specificity of mammalian ALOX15 orthologs is changed during late primate evolution and these alterations might offer evolutionary advantages for hominidae D Heydeck, F Reisch, M Schäfer, KR Kakularam, SA Roigas, S Stehling, ... Frontiers in cell and developmental biology 10, 871585, 2022 | 9 | 2022 |
| Eicosanoid biosynthesis in marine mammals F Reisch, KR Kakularam, S Stehling, D Heydeck, H Kuhn The FEBS journal 288 (4), 1387-1406, 2021 | 9 | 2021 |
| Performance evaluation of docking programs-glide, gold, AutoDock & SurflexDock, using free energy perturbation reference data: a case study of fructose-1, 6-bisphosphatase-AMP … KK Reddy, RS Rathore, P Srujana, RR Burri, CR Reddy, M Sumakanth, ... Mini Reviews in Medicinal Chemistry 20 (12), 1179-1187, 2020 | 8 | 2020 |
| Paralog-and ortholog-specificity of inhibitors of human and mouse lipoxygenase-isoforms KR Kakularam, F Karst, A Polamarasetty, I Ivanov, D Heydeck, H Kuhn Biomedicine & Pharmacotherapy 145, 112434, 2022 | 7 | 2022 |
