IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infection N Kerur, MV Veettil, N Sharma-Walia, V Bottero, S Sadagopan, P Otageri, ... Cell host & microbe 9 (5), 363-375, 2011 | 775 | 2011 |
DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88 V Tarallo, Y Hirano, BD Gelfand, S Dridi, N Kerur, Y Kim, WG Cho, ... Cell 149 (4), 847-859, 2012 | 633 | 2012 |
Nucleoside reverse transcriptase inhibitors possess intrinsic anti-inflammatory activity BJ Fowler, BD Gelfand, Y Kim, N Kerur, V Tarallo, Y Hirano, S Amarnath, ... Science 346 (6212), 1000-1003, 2014 | 229 | 2014 |
cGAS drives noncanonical-inflammasome activation in age-related macular degeneration N Kerur, S Fukuda, D Banerjee, Y Kim, D Fu, I Apicella, A Varshney, ... Nature medicine 24 (1), 50-61, 2018 | 221 | 2018 |
TLR-independent and P2X7-dependent signaling mediate Alu RNA-induced NLRP3 inflammasome activation in geographic atrophy N Kerur, Y Hirano, V Tarallo, BJ Fowler, A Bastos-Carvalho, T Yasuma, ... Investigative ophthalmology & visual science 54 (12), 7395-7401, 2013 | 179 | 2013 |
Kaposi's sarcoma-associated herpesvirus latency in endothelial and B cells activates gamma interferon-inducible protein 16-mediated inflammasomes VV Singh, N Kerur, V Bottero, S Dutta, S Chakraborty, MA Ansari, ... Journal of virology 87 (8), 4417-4431, 2013 | 165 | 2013 |
Kaposi's sarcoma associated herpes virus (KSHV) induced COX-2: a key factor in latency, inflammation, angiogenesis, cell survival and invasion N Sharma-Walia, AG Paul, V Bottero, S Sadagopan, MV Veettil, N Kerur, ... PLoS pathogens 6 (2), e1000777, 2010 | 140 | 2010 |
Genetic characterization of Indian peste des petits ruminants virus (PPRV) by sequencing and phylogenetic analysis of fusion protein and nucleoprotein gene segments N Kerur, MK Jhala, CG Joshi Research in veterinary science 85 (1), 176-183, 2008 | 119 | 2008 |
DICER1/Alu RNA dysmetabolism induces Caspase-8–mediated cell death in age-related macular degeneration Y Kim, V Tarallo, N Kerur, T Yasuma, BD Gelfand, A Bastos-Carvalho, ... Proceedings of the National Academy of Sciences 111 (45), 16082-16087, 2014 | 98 | 2014 |
Emerging nano-formulations and nanomedicines applications for ocular drug delivery D Khiev, ZA Mohamed, R Vichare, R Paulson, S Bhatia, S Mohapatra, ... Nanomaterials 11 (1), 173, 2021 | 94 | 2021 |
Iron toxicity in the retina requires Alu RNA and the NLRP3 inflammasome BD Gelfand, CB Wright, Y Kim, T Yasuma, R Yasuma, S Li, BJ Fowler, ... Cell reports 11 (11), 1686-1693, 2015 | 93 | 2015 |
Interaction of c-Cbl with myosin IIA regulates Bleb associated macropinocytosis of Kaposi's sarcoma-associated herpesvirus M Valiya Veettil, S Sadagopan, N Kerur, S Chakraborty, B Chandran PLoS pathogens 6 (12), e1001238, 2010 | 76 | 2010 |
Characterization of entry and infection of monocytic THP-1 cells by Kaposi's sarcoma associated herpesvirus (KSHV): role of heparan sulfate, DC-SIGN, integrins and signaling N Kerur, MV Veettil, N Sharma-Walia, S Sadagopan, V Bottero, AG Paul, ... Virology 406 (1), 103-116, 2010 | 71 | 2010 |
COX-2/PGE2: molecular ambassadors of Kaposi's sarcoma-associated herpes virus oncoprotein-v-FLIP N Sharma-Walia, K Patel, K Chandran, A Marginean, V Bottero, N Kerur, ... Oncogenesis 1 (4), e5-e5, 2012 | 56 | 2012 |
IL-18 is not therapeutic for neovascular age-related macular degeneration Y Hirano, T Yasuma, T Mizutani, BJ Fowler, V Tarallo, R Yasuma, Y Kim, ... Nature medicine 20 (12), 1372-1375, 2014 | 46 | 2014 |
Piracy of Prostaglandin E2/EP Receptor–Mediated Signaling by Kaposi's Sarcoma-Associated Herpes Virus (HHV-8) for Latency Gene Expression: Strategy of a Successful Pathogen A George Paul, N Sharma-Walia, N Kerur, C White, B Chandran Cancer research 70 (9), 3697-3708, 2010 | 42 | 2010 |
Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration S Fukuda, A Varshney, BJ Fowler, S Wang, S Narendran, K Ambati, ... Proceedings of the National Academy of Sciences 118 (6), e2022751118, 2021 | 41 | 2021 |
Human IgG1 antibodies suppress angiogenesis in a target-independent manner S Bogdanovich, Y Kim, T Mizutani, R Yasuma, L Tudisco, V Cicatiello, ... Signal transduction and targeted therapy 1 (1), 1-14, 2016 | 40 | 2016 |
Kaposi sarcoma-associated herpes virus (KSHV) G protein-coupled receptor (vGPCR) activates the ORF50 lytic switch promoter: a potential positive feedback loop for sustained … V Bottero, N Sharma-Walia, N Kerur, AG Paul, S Sadagopan, M Cannon, ... Virology 392 (1), 34-51, 2009 | 37 | 2009 |
Repurposing anti-inflammasome NRTIs for improving insulin sensitivity and reducing type 2 diabetes development J Ambati, J Magagnoli, H Leung, S Wang, CA Andrews, D Fu, A Pandey, ... Nature Communications 11 (1), 4737, 2020 | 36 | 2020 |