| Rapid-acting antidepressants JM Witkin, AE Martin, LK Golani, NZ Xu, JL Smith Advances in Pharmacology 86, 47-96, 2019 | 59 | 2019 |
| GABAkines–Advances in the discovery, development, and commercialization of positive allosteric modulators of GABAA receptors A Lippa, MM Poe, JL Smith, X Jin, X Ping, LK Golani, JM Cook, JM Witkin Pharmacology & therapeutics 234, 108035, 2022 | 54 | 2022 |
| Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and … LK Golani, A Wallace-Povirk, SM Deis, J Wong, J Ke, X Gu, S Raghavan, ... Journal of medicinal chemistry 59 (17), 7856-7876, 2016 | 44 | 2016 |
| Structure–Activity Profiles of Novel 6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Antifolates with Modified Amino Acids for Cellular Uptake by Folate Receptors α … LK Golani, C George, S Zhao, S Raghavan, S Orr, A Wallace, MR Wilson, ... Journal of medicinal chemistry 57 (19), 8152-8166, 2014 | 37 | 2014 |
| The α2, 3-selective potentiator of GABAA receptors, KRM-II-81, reduces nociceptive-associated behaviors induced by formalin and spinal nerve ligation in rats JM Witkin, R Cerne, PG Davis, KB Freeman, JM Do Carmo, JK Rowlett, ... Pharmacology Biochemistry and Behavior 180, 22-31, 2019 | 32 | 2019 |
| The positive allosteric modulator of α2/3-containing GABAA receptors, KRM-II-81, is active in pharmaco-resistant models of epilepsy and reduces hyperexcitability after … JM Witkin, G Li, LK Golani, W Xiong, JL Smith, X Ping, F Rashid, R Jahan, ... Journal of Pharmacology and Experimental Therapeutics 372 (1), 83-94, 2020 | 24 | 2020 |
| The α2, 3-selective potentiators of GABAA receptors, KRM-II-81 and MP-III-80, produce anxiolytic-like effects and block chemotherapy-induced hyperalgesia in mice without … A Biggerstaff, B Kivell, JL Smith, MY Mian, LK Golani, F Rashid, ... Pharmacology Biochemistry and Behavior 196, 172996, 2020 | 18 | 2020 |
| Effects of the α2/α3-subtype-selective GABAA receptor positive allosteric modulator KRM-II-81 on pain-depressed behavior in rats: comparison with ketorolac and diazepam MJ Moerke, G Li, LK Golani, J Cook, SS Negus Behavioural pharmacology 30 (5), 452-461, 2019 | 17 | 2019 |
| Improved synthesis of anxiolytic, anticonvulsant, and antinociceptive α2/α3-GABA (A)-ergic receptor subtype selective ligands as promising agents to treat anxiety, epilepsy … G Li, LK Golani, R Jahan, F Rashid, JM Cook Synthesis 50 (20), 4124-4132, 2018 | 17 | 2018 |
| An antidepressant-related pharmacological signature for positive allosteric modulators of α2/3-containing GABAA receptors KR Methuku, X Li, R Cerne, SD Gleason, JM Schkeryantz, V Tiruveedhula, ... Pharmacology Biochemistry and Behavior 170, 9-13, 2018 | 16 | 2018 |
| Design, synthesis and biological evaluation of novel pyrrolo [2, 3-d] pyrimidine as tumor-targeting agents with selectivity for tumor uptake by high affinity folate receptors … LK Golani, F Islam, C O'Connor, AS Dekhne, Z Hou, LH Matherly, ... Bioorganic & medicinal chemistry 28 (12), 115544, 2020 | 14 | 2020 |
| Papaverine ameliorates prenatal alcohol‐induced experimental attention deficit hyperactivity disorder by regulating neuronal function, inflammation, and oxidative stress N Sharma, B Sharma, N Dhiman, LK Golani International Journal of Developmental Neuroscience 81 (1), 71-81, 2021 | 11 | 2021 |
| Animal models of fatigue in major depressive disorder PV Stutz, LK Golani, JM Witkin Physiology & behavior 199, 300-305, 2019 | 11 | 2019 |
| Imidazodiazepine anticonvulsant, KRM-II-81, produces novel, non-diazepam-like antiseizure effects DE Knutson, JL Smith, X Ping, X Jin, LK Golani, G Li, ... ACS Chemical Neuroscience 11 (17), 2624-2637, 2020 | 10 | 2020 |
| GABAA Receptor Subtypes and the Abuse‐Related Effects of Ethanol in Rhesus Monkeys: Experiments with Selective Positive Allosteric Modulators LF Berro, D Rüedi‐Bettschen, JE Cook, LK Golani, G Li, R Jahan, ... Alcoholism: Clinical and Experimental Research 43 (5), 791-802, 2019 | 10 | 2019 |
| Involvement of muscarinic receptor mechanisms in antidepressant drug action JM Witkin, JL Smith, LK Golani, EA Brooks, AE Martin Advances in pharmacology 89, 311-356, 2020 | 9 | 2020 |
| Clinical pharmacological innovation in the treatment of depression JM Witkin, LK Golani, JL Smith Expert Review of Clinical Pharmacology 16 (4), 349-362, 2023 | 8 | 2023 |
| Non-sedating benzodiazepines cause paralysis and tissue damage in the parasitic blood fluke Schistosoma mansoni P McCusker, MY Mian, G Li, MD Olp, VVNPB Tiruveedhula, F Rashid, ... PLoS Neglected Tropical Diseases 13 (11), e0007826, 2019 | 8 | 2019 |
| The value of human epileptic tissue in the characterization and development of novel antiepileptic drugs: The example of CERC-611 and KRM-II-81 JM Witkin, X Ping, C Mouser, X Jin, J Hobbs, VVNPB Tiruveedhula, G Li, ... Brain research 1722, 146356, 2019 | 8 | 2019 |
| Rationalizing the binding and α subtype selectivity of synthesized imidazodiazepines and benzodiazepines at GABAA receptors by using molecular docking studies LK Golani, MY Mian, T Ahmed, KP Pandey, P Mondal, D Sharmin, ... Bioorganic & Medicinal Chemistry Letters 62, 128637, 2022 | 7 | 2022 |
james cookProfessor of Chemistry, University of Wisconsin MilwaukeeVerified email at uwm.edu
