Long-term clinical efficacy of grass-pollen immunotherapy SR Durham, SM Walker, EM Varga, MR Jacobson, F O'Brien, W Noble, ... New England Journal of Medicine 341 (7), 468-475, 1999 | 1844 | 1999 |
Tau phosphorylation: the therapeutic challenge for neurodegenerative disease DP Hanger, BH Anderton, W Noble Trends in molecular medicine 15 (3), 112-119, 2009 | 1114 | 2009 |
Roles of tau protein in health and disease T Guo, W Noble, DP Hanger Acta neuropathologica 133, 665-704, 2017 | 950 | 2017 |
Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo W Noble, E Planel, C Zehr, V Olm, J Meyerson, F Suleman, K Gaynor, ... Proceedings of the national academy of sciences 102 (19), 6990-6995, 2005 | 918 | 2005 |
Physiological release of endogenous tau is stimulated by neuronal activity AM Pooler, EC Phillips, DHW Lau, W Noble, DP Hanger EMBO reports 14 (4), 389-394, 2013 | 636 | 2013 |
Cdk5 is a key factor in tau aggregation and tangle formation in vivo W Noble, V Olm, K Takata, E Casey, O Mary, J Meyerson, K Gaynor, ... Neuron 38 (4), 555-565, 2003 | 584 | 2003 |
The importance of tau phosphorylation for neurodegenerative diseases W Noble, DP Hanger, CCJ Miller, S Lovestone Frontiers in neurology 4, 83, 2013 | 459 | 2013 |
International, randomized, controlled trial of lamifiban (a platelet glycoprotein IIb/IIIa inhibitor), heparin, or both in unstable angina E Topol, R Califf, F Van de Werf, R Diaz, E Paolasso, P Aylward, J Simes, ... Circulation 97 (24), 2386-2395, 1998 | 431 | 1998 |
Astrocytes are important mediators of Aβ-induced neurotoxicity and tau phosphorylation in primary culture CJ Garwood, AM Pooler, J Atherton, DP Hanger, W Noble Cell death & disease 2 (6), e167-e167, 2011 | 389 | 2011 |
The ER-mitochondria tethering complex VAPB-PTPIP51 regulates autophagy P Gomez-Suaga, S Paillusson, R Stoica, W Noble, DP Hanger, CCJ Miller Current Biology 27 (3), 371-385, 2017 | 355 | 2017 |
α-Synuclein binds to the ER–mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP production S Paillusson, P Gomez-Suaga, R Stoica, D Little, P Gissen, MJ Devine, ... Acta neuropathologica 134, 129-149, 2017 | 331 | 2017 |
A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes GUSTO IIb Investigators N Engl J Med 335, 775-782, 1996 | 302 | 1996 |
Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway R Killick, EM Ribe, R Al-Shawi, B Malik, C Hooper, C Fernandes, ... Molecular psychiatry 19 (1), 88-98, 2014 | 256 | 2014 |
ALS/FTD‐associated FUS activates GSK‐3β to disrupt the VAPB–PTPIP 51 interaction and ER–mitochondria associations R Stoica, S Paillusson, P Gomez‐Suaga, JC Mitchell, DHW Lau, EH Gray, ... EMBO reports 17 (9), 1326-1342, 2016 | 253 | 2016 |
A role for tau at the synapse in Alzheimer's disease pathogenesis AM Pooler, W Noble, DP Hanger Neuropharmacology 76, 1-8, 2014 | 234 | 2014 |
Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase P Derkinderen, TME Scales, DP Hanger, KY Leung, HL Byers, MA Ward, ... Journal of Neuroscience 25 (28), 6584-6593, 2005 | 230 | 2005 |
Presenilin redistribution associated with aberrant cholesterol transport enhances β-amyloid production in vivo M Burns, K Gaynor, V Olm, M Mercken, J LaFrancois, L Wang, ... Journal of Neuroscience 23 (13), 5645-5649, 2003 | 225 | 2003 |
Tau phosphorylation affects its axonal transport and degradation T Rodríguez-Martín, I Cuchillo-Ibáñez, W Noble, F Nyenya, BH Anderton, ... Neurobiology of aging 34 (9), 2146-2157, 2013 | 205 | 2013 |
Collapsin response mediator protein‐2 hyperphosphorylation is an early event in Alzheimer’s disease progression AR Cole, W Noble, L Aalten, F Plattner, R Meimaridou, D Hogan, M Taylor, ... Journal of neurochemistry 103 (3), 1132-1144, 2007 | 201 | 2007 |
Molecular motors implicated in the axonal transport of tau and α-synuclein MA Utton, WJ Noble, JE Hill, BH Anderton, DP Hanger Journal of cell science 118 (20), 4645-4654, 2005 | 186 | 2005 |