Molecular mechanisms of lipotoxicity and glucotoxicity in nonalcoholic fatty liver disease M Mota, BA Banini, SC Cazanave, AJ Sanyal Metabolism 65 (8), 1049-1061, 2016 | 505 | 2016 |
A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer A Asgharpour, SC Cazanave, T Pacana, M Seneshaw, R Vincent, ... Journal of hepatology 65 (3), 579-588, 2016 | 492 | 2016 |
Fast food diet mouse: novel small animal model of NASH with ballooning, progressive fibrosis, and high physiological fidelity to the human condition M Charlton, A Krishnan, K Viker, S Sanderson, S Cazanave, A McConico, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 301 (5 …, 2011 | 456 | 2011 |
Transcriptional suppression of mir‐29b‐1/mir‐29a promoter by c‐Myc, hedgehog, and NF‐kappaB JL Mott, S Kurita, SC Cazanave, SF Bronk, NW Werneburg, ... Journal of cellular biochemistry 110 (5), 1155-1164, 2010 | 355 | 2010 |
The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids P Puri, K Daita, A Joyce, F Mirshahi, PK Santhekadur, S Cazanave, ... Hepatology 67 (2), 534-548, 2018 | 354 | 2018 |
The manganese superoxide dismutase Ala16Val dimorphism modulates both mitochondrial import and mRNA stability A Sutton, A Imbert, A Igoudjil, V Descatoire, S Cazanave, D Pessayre, ... Pharmacogenetics and genomics 15 (5), 311-319, 2005 | 292 | 2005 |
Palmitoleate attenuates palmitate-induced Bim and PUMA up-regulation and hepatocyte lipoapoptosis Y Akazawa, S Cazanave, JL Mott, N Elmi, SF Bronk, S Kohno, ... Journal of hepatology 52 (4), 586-593, 2010 | 276 | 2010 |
Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis K Kakisaka, SC Cazanave, CD Fingas, ME Guicciardi, SF Bronk, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 302 (1 …, 2012 | 236 | 2012 |
JNK1-dependent PUMA expression contributes to hepatocyte lipoapoptosis SC Cazanave, JL Mott, NA Elmi, SF Bronk, NW Werneburg, Y Akazawa, ... Journal of Biological Chemistry 284 (39), 26591-26602, 2009 | 230 | 2009 |
CHOP and AP-1 cooperatively mediate PUMA expression during lipoapoptosis SC Cazanave, NA Elmi, Y Akazawa, SF Bronk, JL Mott, GJ Gores American Journal of Physiology-Gastrointestinal and Liver Physiology 299 (1 …, 2010 | 228 | 2010 |
Myofibroblast‐derived PDGF‐BB promotes Hedgehog survival signaling in cholangiocarcinoma cells CD Fingas, SF Bronk, NW Werneburg, JL Mott, ME Guicciardi, ... Hepatology 54 (6), 2076-2088, 2011 | 163 | 2011 |
Dysregulated hepatic methionine metabolism drives homocysteine elevation in diet-induced nonalcoholic fatty liver disease T Pacana, S Cazanave, A Verdianelli, V Patel, HK Min, F Mirshahi, ... PloS one 10 (8), e0136822, 2015 | 144 | 2015 |
Death receptor 5 signaling promotes hepatocyte lipoapoptosis SC Cazanave, JL Mott, SF Bronk, NW Werneburg, CD Fingas, XW Meng, ... Journal of Biological Chemistry 286 (45), 39336-39348, 2011 | 136 | 2011 |
Mechanisms and clinical implications of hepatocyte lipoapoptosis SC Cazanave, GJ Gores Clinical lipidology 5 (1), 71-85, 2010 | 120 | 2010 |
Glycogen synthase kinase-3 (GSK-3) inhibition attenuates hepatocyte lipoapoptosis SH Ibrahim, Y Akazawa, SC Cazanave, SF Bronk, NA Elmi, ... Journal of hepatology 54 (4), 765-772, 2011 | 97 | 2011 |
A role for miR-296 in the regulation of lipoapoptosis by targeting PUMA [S] SC Cazanave, JL Mott, NA Elmi, SF Bronk, HC Masuoka, MR Charlton, ... Journal of lipid research 52 (8), 1517-1525, 2011 | 96 | 2011 |
High hepatic glutathione stores alleviate Fas-induced apoptosis in mice S Cazanave, A Berson, D Haouzi, N Vadrot, D Fau, A Grodet, P Lettéron, ... Journal of hepatology 46 (5), 858-868, 2007 | 72 | 2007 |
A hedgehog survival pathway in ‘undead’lipotoxic hepatocytes K Kakisaka, SC Cazanave, NW Werneburg, N Razumilava, JC Mertens, ... Journal of hepatology 57 (4), 844-851, 2012 | 69 | 2012 |
The anti-inflammatory drug, nimesulide (4-nitro-2-phenoxymethane-sulfoanilide), uncouples mitochondria and induces mitochondrial permeability transition in human hepatoma cells … A Berson, S Cazanave, V Descatoire, M Tinel, A Grodet, C Wolf, ... Journal of Pharmacology and Experimental Therapeutics 318 (1), 444-454, 2006 | 64 | 2006 |
Saturated free fatty acids induce cholangiocyte lipoapoptosis SK Natarajan, SA Ingham, AM Mohr, CJ Wehrkamp, A Ray, S Roy, ... Hepatology 60 (6), 1942-1956, 2014 | 62 | 2014 |