Ole D. Madsen
Ole D. Madsen
Retired from Hagedorn Research, Novo Nordisk A/S
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Hypothalamic CART is a new anorectic peptide regulated by leptin
P Kristensen, ME Judge, L Thim, U Ribel, KN Christjansen, BS Wulff, ...
Nature 393 (6680), 72-76, 1998
Control of endodermal endocrine development by Hes-1
J Jensen, EE Pedersen, P Galante, J Hald, RS Heller, M Ishibashi, ...
Nature genetics 24 (1), 36-44, 2000
Independent development of pancreatic alpha-and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation.
J Jensen, RS Heller, T Funder-Nielsen, EE Pedersen, C Lindsell, ...
Diabetes 49 (2), 163-176, 2000
The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into α and subsequently β cells
P Collombat, X Xu, P Ravassard, B Sosa-Pineda, S Dussaud, N Billestrup, ...
Cell 138 (3), 449-462, 2009
An illustrated review of early pancreas development in the mouse
MC J°rgensen, J Ahnfelt-R°nne, J Hald, OD Madsen, P Serup, ...
Endocrine reviews 28 (6), 685-705, 2007
Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3
P Jacquemin, SM Durviaux, J Jensen, C Godfraind, G Gradwohl, ...
Molecular and cellular biology 20 (12), 4445-4454, 2000
Conversion of proinsulin to insulin occurs coordinately with acidification of maturing secretory vesicles.
L Orci, M Ravazzola, M Amherdt, O Madsen, A Perrelet, JD Vassalli, ...
Journal of Cell Biology 103 (6), 2273-2281, 1986
Direct identification of prohormone conversion site in insulin-secreting cells
L Orci, M Ravazzola, M Amherdt, O Madsen, JD Vassalli, A Perrelet
Cell 42 (2), 671-681, 1985
Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development
J Hald, JP Hjorth, MS German, OD Madsen, P Serup, J Jensen
Developmental biology 260 (2), 426-437, 2003
mRNA profiling of rat islet tumors reveals Nkx 6.1 as a β-cell-specific homeodomain transcription factor
J Jensen, P Serup, C Karlsen, TF Nielsen, OD Madsen
Journal of Biological Chemistry 271 (31), 18749-18758, 1996
Transcriptional regulation of the human insulin gene is dependent on the homeodomain protein STF1/IPF1 acting through the CT boxes
HV Petersen, P Serup, J Leonard, BK Michelsen, OD Madsen
Proceedings of the National Academy of Sciences 91 (22), 10465-10469, 1994
Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3
Y Heremans, M Van De Casteele, P in't Veld, G Gradwohl, P Serup, ...
The Journal of cell biology 159 (2), 303-312, 2002
The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells.
A Ammendrup, A Maillard, K Nielsen, NA Andersen, P Serup, OD Madsen, ...
Diabetes 49 (9), 1468-1476, 2000
The insulin gene promoter: a simplified nomenclature
M German, S Ashcroft, K Docherty, H Edlund, T Edlund, S Goodison, ...
Diabetes 44 (8), 1002-1004, 1995
Differential expression of the two nonallelic proinsulin genes in the developing mouse embryo.
L Deltour, P Leduque, N Blume, O Madsen, P Dubois, J Jami, D Bucchini
Proceedings of the National Academy of Sciences 90 (2), 527-531, 1993
Genetic determinants of pancreatic ε-cell development
RS Heller, M Jenny, P Collombat, A Mansouri, C Tomasetto, OD Madsen, ...
Developmental biology 286 (1), 217-224, 2005
Expression patterns of Wnts, Frizzleds, sFRPs, and misexpression in transgenic mice suggesting a role for Wnts in pancreas and foregut pattern formation
RS Heller, DS Dichmann, J Jensen, C Miller, G Wong, OD Madsen, ...
Developmental dynamics: an official publication of the American Associationá…, 2002
Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1
P Serup, J Jensen, FG Andersen, MC J°rgensen, N Blume, JJ Holst, ...
Proceedings of the National Academy of Sciences 93 (17), 9015-9020, 1996
Long-term GABA administration induces alpha cell-mediated beta-like cell neogenesis
N Ben-Othman, A Vieira, M Courtney, F Record, E Gjernes, F Avolio, ...
Cell 168 (1-2), 73-85. e11, 2017
The glucose sensor protein glucokinase is expressed in glucagon-producing alpha-cells
H Heimberg, A De Vos, K Moens, E Quartier, L Bouwens, D Pipeleers, ...
Proceedings of the National Academy of Sciences 93 (14), 7036-7041, 1996
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