|Induction of detoxifying enzymes by garlic organosulfur compounds through transcription factor Nrf2: effect of chemical structure and stress signals|
C Chen, D Pung, V Leong, V Hebbar, G Shen, S Nair, W Li, ANT Kong
Free Radical Biology and Medicine 37 (10), 1578-1590, 2004
|Regulation of Nrf2 transactivation domain activity: the differential effects of mitogen-activated protein kinase cascades and synergistic stimulatory effect of Raf and CREB …|
G Shen, V Hebbar, S Nair, C Xu, W Li, W Lin, YS Keum, J Han, MA Gallo, ...
Journal of Biological Chemistry 279 (22), 23052-23060, 2004
|ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells|
C Xu, G Shen, X Yuan, J Kim, A Gopalkrishnan, YS Keum, S Nair, ...
Carcinogenesis 27 (3), 437-445, 2006
|Natural dietary anti‐cancer chemopreventive compounds: redox‐mediated differential signaling mechanisms in cytoprotection of normal cells versus cytotoxicity in tumor cells 1|
S Nair, W Li, ANT KONG
Acta Pharmacologica Sinica 28 (4), 459-472, 2007
|Comparison of (−)-epigallocatechin-3-gallate elicited liver and small intestine gene expression profiles between C57BL/6J mice and C57BL/6J/Nrf2 (−/−) mice|
G Shen, C Xu, R Hu, MR Jain, S Nair, W Lin, CS Yang, JY Chan, ...
Pharmaceutical research 22 (11), 1805-1820, 2005
|Chemoprevention of familial adenomatous polyposis by natural dietary compounds sulforaphane and dibenzoylmethane alone and in combination in ApcMin/+ mouse|
G Shen, TO Khor, R Hu, S Yu, S Nair, CT Ho, BS Reddy, MT Huang, ...
Cancer research 67 (20), 9937-9944, 2007
|Modulation of nuclear factor E2-related factor 2–mediated gene expression in mice liver and small intestine by cancer chemopreventive agent curcumin|
G Shen, C Xu, R Hu, MR Jain, A Gopalkrishnan, S Nair, MT Huang, ...
Molecular cancer therapeutics 5 (1), 39-51, 2006
|Regulatory potential for concerted modulation of Nrf2-and Nfkb1-mediated gene expression in inflammation and carcinogenesis|
S Nair, ST Doh, JY Chan, AN Kong, L Cai
British journal of cancer 99 (12), 2070-2082, 2008
|Effects of glutathione on antioxidant response element-mediated gene expression and apoptosis elicited by sulforaphane|
BR Kim, R Hu, YS Keum, V Hebbar, G Shen, SS Nair, ANT Kong
Cancer Research 63 (21), 7520-7525, 2003
|γ‐Tocopherol‐enriched mixed tocopherol diet inhibits prostate carcinogenesis in TRAMP mice|
A Barve, TO Khor, S Nair, K Reuhl, N Suh, B Reddy, H Newmark, ...
International journal of cancer 124 (7), 1693-1699, 2009
|Modulation of activator protein-1 (AP-1) and MAPK pathway by flavonoids in human prostate cancer PC3 cells|
A Gopalakrishnan, CJ Xu, SS Nair, C Chen, V Hebbar, ANT Kong
Archives of pharmacal research 29 (8), 633-644, 2006
|Structural influence of isothiocyanates on the antioxidant response element (ARE)-mediated heme oxygenase-1 (HO-1) expression|
A Prawan, YS Keum, TO Khor, S Yu, S Nair, W Li, L Hu, ANT Kong
Pharmaceutical research 25 (4), 836-844, 2008
|Pharmacogenomics of phenolic antioxidant butylated hydroxyanisole (BHA) in the small intestine and liver of Nrf2 knockout and C57BL/6J mice|
S Nair, C Xu, G Shen, V Hebbar, A Gopalakrishnan, R Hu, MR Jain, W Lin, ...
Pharmaceutical research 23 (11), 2621-2637, 2006
|Regulation of Nrf2-and AP-1-mediated gene expression by epigallocatechin-3-gallate and sulforaphane in prostate of Nrf2-knockout or C57BL/6J mice and PC-3 AP-1 human prostate …|
S Nair, A Barve, TO Khor, G Shen, W Lin, JY Chan, L Cai, AN Kong
Acta Pharmacologica Sinica 31 (9), 1223-1240, 2010
|Pharmacogenomics of cancer chemopreventive isothiocyanate compound sulforaphane in the intestinal polyps of ApcMin/+ mice|
TO Khor, R Hu, G Shen, WS Jeong, V Hebbar, C Chen, C Xu, S Nair, ...
Biopharmaceutics & drug disposition 27 (9), 407-420, 2006
|Synergistic effects of a combination of dietary factors sulforaphane and (−) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells|
S Nair, V Hebbar, G Shen, A Gopalakrishnan, TO Khor, S Yu, C Xu, ...
Pharmaceutical research 25 (2), 387-399, 2008
|Toxicogenomics of endoplasmic reticulum stress inducer tunicamycin in the small intestine and liver of Nrf2 knockout and C57BL/6J mice|
S Nair, C Xu, G Shen, V Hebbar, A Gopalakrishnan, R Hu, MR Jain, ...
Toxicology letters 168 (1), 21-39, 2007
|Emerging roles for modulation of microRNA signatures in cancer chemoprevention|
K Neelakandan, P Babu, S Nair
Current cancer drug targets 12 (6), 716-740, 2012
|Pharmacogenomic profile of soy isoflavone concentrate in the prostate of Nrf2 deficient and wild‐type mice|
A Barve, TO Khor, S Nair, W Lin, S Yu, MR Jain, JY Chan, AN Kong
Journal of pharmaceutical sciences 97 (10), 4528-4545, 2008
|In vivo pharmacokinetics, activation of MAPK signaling and induction of phase II/III drug metabolizing enzymes/transporters by cancer chemopreventive compound BHA in the mice|
R Hu, G Shen, UR Yerramilli, W Lin, C Xu, S Nair, ANT Kong
Archives of pharmacal research 29 (10), 911-920, 2006