Caspase-11–mediated endothelial pyroptosis underlies endotoxemia-induced lung injury KT Cheng, S Xiong, Z Ye, Z Hong, A Di, KM Tsang, X Gao, S An, M Mittal, ... The Journal of clinical investigation 127 (11), 4124-4135, 2017 | 360 | 2017 |
The role of germline AIP, MEN1, PRKAR1A, CDKN1B and CDKN2C mutations in causing pituitary adenomas in a large cohort of children, adolescents, and … CA Stratakis, MA Tichomirowa, S Boikos, MF Azevedo, M Lodish, ... Clinical genetics 78 (5), 457-463, 2010 | 220 | 2010 |
The role of germline AIP, MEN1, PRKAR1A, CDKN1B and CDKN2C mutations in causing pituitary adenomas in a large cohort of children, adolescents, and … CA Stratakis, MA Tichomirowa, S Boikos, MF Azevedo, M Lodish, ... Clinical genetics 78 (5), 457-463, 2010 | 220 | 2010 |
Mutations and polymorphisms in the gene encoding regulatory subunit type 1‐alpha of protein kinase A (PRKAR1A): an update A Horvath, J Bertherat, L Groussin, M Guillaud‐Bataille, K Tsang, ... Human mutation 31 (4), 369-379, 2010 | 197 | 2010 |
A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex A Horvath, C Giatzakis, K Tsang, E Greene, P Osorio, S Boikos, R Libè, ... European Journal of Human Genetics 16 (10), 1245-1253, 2008 | 118 | 2008 |
Functional phosphodiesterase 11A mutations may modify the risk of familial and bilateral testicular germ cell tumors A Horvath, L Korde, MH Greene, R Libe, P Osorio, FR Faucz, ... Cancer research 69 (13), 5301-5306, 2009 | 94 | 2009 |
Extensive ex vivo expansion of functional human erythroid precursors established from umbilical cord blood cells by defined factors X Huang, S Shah, J Wang, Z Ye, SN Dowey, KM Tsang, LG Mendelsohn, ... Molecular Therapy 22 (2), 451-463, 2014 | 73 | 2014 |
Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/− or Rb1+/− backgrounds and chemically induced skin papillomas by dysregulation of the … MQ Almeida, M Muchow, S Boikos, AJ Bauer, KJ Griffin, KM Tsang, ... Human molecular genetics 19 (8), 1387-1398, 2010 | 73 | 2010 |
Histone demethylases KDM4A and KDM4C regulate differentiation of embryonic stem cells to endothelial cells L Wu, KK Wary, S Revskoy, X Gao, K Tsang, YA Komarova, J Rehman, ... Stem cell reports 5 (1), 10-21, 2015 | 55 | 2015 |
Whole-genome sequencing identifies genetic variances in culture-expanded human mesenchymal stem cells J Cai, X Miao, Y Li, C Smith, K Tsang, L Cheng, Q Wang Stem cell reports 3 (2), 227-233, 2014 | 52 | 2014 |
Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone KM Tsang, MF Starost, M Nesterova, SA Boikos, T Watkins, MQ Almeida, ... Proceedings of the National Academy of Sciences 107 (19), 8683-8688, 2010 | 52 | 2010 |
Minoxidil improves vascular compliance, restores cerebral blood flow, and alters extracellular matrix gene expression in a model of chronic vascular stiffness RH Knutsen, SC Beeman, TJ Broekelmann, D Liu, KM Tsang, A Kovacs, ... American Journal of Physiology-Heart and Circulatory Physiology 315 (1), H18-H32, 2018 | 51 | 2018 |
Embryonic stem cell differentiation to functional arterial endothelial cells through sequential activation of ETV2 and NOTCH1 signaling by HIF1α KM Tsang, JS Hyun, KT Cheng, M Vargas, D Mehta, M Ushio-Fukai, L Zou, ... Stem cell reports 9 (3), 796-806, 2017 | 48 | 2017 |
Protein kinase A regulates caspase-1 via Ets-1 in bone stromal cell-derived lesions: a link between cyclic AMP and pro-inflammatory pathways in osteoblast progenitors MQ Almeida, KM Tsang, C Cheadle, T Watkins, JC Grivel, M Nesterova, ... Human molecular genetics 20 (1), 165-175, 2011 | 42 | 2011 |
Efficient derivation and genetic modifications of human pluripotent stem cells on engineered human feeder cell lines C Zou, BK Chou, SN Dowey, K Tsang, X Huang, CF Liu, C Smith, J Yen, ... Stem cells and development 21 (12), 2298-2311, 2012 | 40 | 2012 |
In Vitro Studies of Novel PRKAR1A Mutants that Extend the Predicted RIα Protein Sequence into the 3′-Untranslated Open Reading Frame: Proteasomal … Y Patronas, A Horvath, E Greene, K Tsang, E Bimpaki, M Haran, ... The Journal of Clinical Endocrinology & Metabolism 97 (3), E496-E502, 2012 | 28 | 2012 |
Inhibition of NOX1 mitigates blood pressure increases in elastin insufficiency A Troia, RH Knutsen, CM Halabi, D Malide, ZX Yu, A Wardlaw-Pickett, ... Function 2 (3), zqab015, 2021 | 13 | 2021 |
Hematopoietic neoplasms in Prkar2a-deficient mice E Saloustros, P Salpea, CF Qi, LA Gugliotti, K Tsang, S Liu, MF Starost, ... Journal of Experimental & Clinical Cancer Research 34, 1-8, 2015 | 10 | 2015 |
Haploinsufficiency for either one of the type-II regulatory subunits of protein kinase A improves the bone phenotype of Prkar1a+/− mice S Liu, E Saloustros, EL Mertz, K Tsang, MF Starost, P Salpea, FR Faucz, ... Human molecular genetics 24 (21), 6080-6092, 2015 | 10 | 2015 |
Copper-binding domain variation in a novel murine lysyl oxidase model produces structurally inferior aortic elastic fibers whose failure is modified by age, sex, and blood pressure KM Tsang, RH Knutsen, CJ Billington Jr, E Lindberg, H Steenbock, YP Fu, ... International journal of molecular sciences 23 (12), 6749, 2022 | 4 | 2022 |