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The molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule
BCS Cross, PJ Bond, PG Sadowski, BK Jha, J Zak, JM Goodman, ...
Proceedings of the National Academy of Sciences 109 (15), E869-E878, 2012
New insights into the role of RNase L in innate immunity
A Chakrabarti, BK Jha, RH Silverman
Journal of Interferon & Cytokine Research 31 (1), 49-57, 2011
Nucleoside modifications in RNA limit activation of 2′-5′-oligoadenylate synthetase and increase resistance to cleavage by RNase L
BR Anderson, H Muramatsu, BK Jha, RH Silverman, D Weissman, ...
Nucleic acids research 39 (21), 9329-9338, 2011
Antagonism of the interferon-induced OAS-RNase L pathway by murine coronavirus ns2 protein is required for virus replication and liver pathology
L Zhao, BK Jha, A Wu, R Elliott, J Ziebuhr, AE Gorbalenya, RH Silverman, ...
Cell host & microbe 11 (6), 607-616, 2012
West Nile virus noncoding subgenomic RNA contributes to viral evasion of the type I interferon-mediated antiviral response
A Schuessler, A Funk, HM Lazear, DA Cooper, S Torres, S Daffis, BK Jha, ...
Journal of virology 86 (10), 5708-5718, 2012
Homologous 2′, 5′-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity
R Zhang, BK Jha, KM Ogden, B Dong, L Zhao, R Elliott, JT Patton, ...
Proceedings of the National Academy of Sciences 110 (32), 13114-13119, 2013
Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLI-DNA binding
A Agyeman, BK Jha, T Mazumdar, JA Houghton
Oncotarget 5 (12), 4492, 2014
Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity
H Huang, E Zeqiraj, B Dong, BK Jha, NM Duffy, S Orlicky, ...
Molecular cell 53 (2), 221-234, 2014
Middle East respiratory syndrome coronavirus NS4b protein inhibits host RNase L activation
JM Thornbrough, BK Jha, B Yount, SA Goldstein, Y Li, R Elliott, AC Sims, ...
MBio 7 (2), 10.1128/mbio. 00258-16, 2016
Small-molecule activators of RNase L with broad-spectrum antiviral activity
CS Thakur, BK Jha, B Dong, J Das Gupta, KM Silverman, H Mao, H Sawai, ...
Proceedings of the National Academy of Sciences 104 (23), 9585-9590, 2007
Leukemogenic nucleophosmin mutation disrupts the transcription factor hub that regulates granulomonocytic fates
X Gu, Q Ebrahem, RZ Mahfouz, M Hasipek, F Enane, T Radivoyevitch, ...
The Journal of clinical investigation 128 (10), 4260-4279, 2018
Novel protein disulfide isomerase inhibitor with anticancer activity in multiple myeloma
S Vatolin, JG Phillips, BK Jha, S Govindgari, J Hu, D Grabowski, Y Parker, ...
Cancer research 76 (11), 3340-3350, 2016
A phylogenetically conserved RNA structure in the poliovirus open reading frame inhibits the antiviral endoribonuclease RNase L
JQ Han, HL Townsend, BK Jha, JM Paranjape, RH Silverman, DJ Barton
Journal of virology 81 (11), 5561-5572, 2007
Inhibition of RNase L and RNA-dependent protein kinase (PKR) by sunitinib impairs antiviral innate immunity
BK Jha, I Polyakova, P Kessler, B Dong, B Dickerman, GC Sen, ...
Journal of Biological Chemistry 286 (30), 26319-26326, 2011
Suppression of antiviral innate immunity by sunitinib enhances oncolytic virotherapy
BK Jha, B Dong, CT Nguyen, I Polyakova, RH Silverman
Molecular Therapy 21 (9), 1749-1757, 2013
Evasion of antiviral innate immunity by Theiler's virus L* protein through direct inhibition of RNase L
F Sorgeloos, BK Jha, RH Silverman, T Michiels
PLoS pathogens 9 (6), e1003474, 2013
Hepatitis C virus RNA: dinucleotide frequencies and cleavage by RNase L
CL Washenberger, JQ Han, KJ Kechris, BK Jha, RH Silverman, DJ Barton
Virus research 130 (1-2), 85-95, 2007
Decitabine-and 5-azacytidine resistance emerges from adaptive responses of the pyrimidine metabolism network
X Gu, R Tohme, B Tomlinson, N Sakre, M Hasipek, L Durkin, C Schuerger, ...
Leukemia 35 (4), 1023-1036, 2021
Ribonuclease L and metal-ion–independent endoribonuclease cleavage sites in host and viral RNAs
DA Cooper, BK Jha, RH Silverman, JR Hesselberth, DJ Barton
Nucleic acids research 42 (8), 5202-5216, 2014
Consequences of mutant TET2 on clonality and subclonal hierarchy
CM Hirsch, A Nazha, K Kneen, ME Abazeed, M Meggendorfer, ...
Leukemia 32 (8), 1751-1761, 2018
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