A novel polymorphism in the 1A promoter region of the vitamin D receptor is associated with altered susceptibilty and prognosis in malignant melanoma JA Halsall, JE Osborne, L Potter, JH Pringle, PE Hutchinson British journal of cancer 91 (4), 765-770, 2004 | 129 | 2004 |
Vitamin D receptor gene polymorphisms, particularly the novel A-1012G promoter polymorphism, are associated with vitamin D3 responsiveness and non-familial susceptibility in … JA Halsall, JE Osborne, JH Pringle, PE Hutchinson Pharmacogenetics and genomics 15 (5), 349-355, 2005 | 102 | 2005 |
Histone deacetylase inhibitors for cancer therapy: An evolutionarily ancient resistance response may explain their limited success JA Halsall, BM Turner Bioessays 38 (11), 1102-1110, 2016 | 88 | 2016 |
Relative overexpression of X-linked genes in mouse embryonic stem cells is consistent with Ohno's hypothesis H Lin, JA Halsall, P Antczak, LP O'Neill, F Falciani, BM Turner Nature genetics 43 (12), 1169-1170, 2011 | 80 | 2011 |
Genes are often sheltered from the global histone hyperacetylation induced by HDAC inhibitors J Halsall, V Gupta, LP O'Neill, BM Turner, KP Nightingale PloS one 7 (3), e33453, 2012 | 69 | 2012 |
Immunostaining of modified histones defines high-level features of the human metaphase epigenome E Terrenoire, F McRonald, JA Halsall, P Page, RS Illingworth, AMR Taylor, ... Genome biology 11, 1-14, 2010 | 65 | 2010 |
Cells adapt to the epigenomic disruption caused by histone deacetylase inhibitors through a coordinated, chromatin-mediated transcriptional response JA Halsall, N Turan, M Wiersma, BM Turner Epigenetics & chromatin 8, 1-16, 2015 | 58 | 2015 |
The histone deacetylase inhibitor sodium valproate causes limited transcriptional change in mouse embryonic stem cells but selectively overrides Polycomb-mediated Hoxb silencing E Boudadi, H Stower, JA Halsall, CE Rutledge, M Leeb, A Wutz, ... Epigenetics & chromatin 6, 1-16, 2013 | 42 | 2013 |
The unfavorable effect of the A allele of the vitamin D receptor promoter polymorphism A-1012G has different mechanisms related to susceptibility and outcome of malignant melanoma JA Halsall, JE Osborne, MP Epstein, JH Pringle, PE Hutchinson Dermato-endocrinology 1 (1), 54-57, 2009 | 39 | 2009 |
Protein kinase Msk1 physically and functionally interacts with the KMT2A/MLL1 methyltransferase complex and contributes to the regulation of multiple target genes M Wiersma, M Bussiere, JA Halsall, N Turan, R Slany, BM Turner, ... Epigenetics & Chromatin 9, 1-12, 2016 | 29 | 2016 |
Proline-Rich Homeodomain protein (PRH/HHEX) is a suppressor of breast tumour growth RM Kershaw, D Roberts, J Wragg, AM Shaaban, E Humphreys, J Halsall, ... Oncogenesis 6 (6), e346-e346, 2017 | 27 | 2017 |
A novel form of JARID2 is required for differentiation in lineage‐committed cells D Al‐Raawi, R Jones, S Wijesinghe, J Halsall, M Petric, S Roberts, ... The EMBO journal 38 (3), e98449, 2019 | 23 | 2019 |
In silico analysis of the 5′ region of the Vitamin D receptor gene: functional implications of evolutionary conservation JA Halsall, JE Osborne, PE Hutchinson, JH Pringle The Journal of steroid biochemistry and molecular biology 103 (3-5), 352-356, 2007 | 19 | 2007 |
Compromised vitamin D receptor signalling in malignant melanoma is associated with tumour progression and mitogen-activated protein kinase activity PE Hutchinson, JA Halsall, S Popovici, E Papadogeorgakis, JE Osborne, ... Melanoma Research 28 (5), 410-422, 2018 | 13 | 2018 |
Histone modifications form a cell-type-specific chromosomal bar code that persists through the cell cycle JA Halsall, S Andrews, F Krueger, CE Rutledge, G Ficz, W Reik, ... Scientific reports 11 (1), 3009, 2021 | 12 | 2021 |
A long intergenic non-coding RNA regulates nuclear localization of DNA methyl transferase-1 R Jones, S Wijesinghe, C Wilson, J Halsall, T Liloglou, A Kanhere Iscience 24 (4), 2021 | 11 | 2021 |
Immunolabelling of human metaphase chromosomes reveals the same banded distribution of histone H3 isoforms methylated at lysine 4 in primary lymphocytes and cultured cell lines E Terrenoire, JA Halsall, BM Turner BMC genetics 16, 1-7, 2015 | 6 | 2015 |
Morphine leads to global genome changes in H3K27me3 levels via a Polycomb Repressive Complex 2 (PRC2) self-regulatory mechanism in mESCs I Muñoa-Hoyos, JA Halsall, M Araolaza, C Ward, I Garcia, ... Clinical epigenetics 12, 1-13, 2020 | 5 | 2020 |
Histone modifications form a cell-type-specific chromosomal bar code that modulates and maintains patterns of gene expression through the cell cycle JA Halsall, S Andrews, F Krueger, CE Rutledge, G Ficz, W Reik, ... bioRxiv, 2020.10. 16.341446, 2020 | | 2020 |
ChIP-seq reveals a different genomic distribution of epigenetic mark H3K27me3 at ICR/DMRs of imprinted genes induced by morphine in mouse Embryonic Stem Cells (mESCs) I Munoa, M Gianzo, J Halsall, C Ward, P Garcia, B Turner, N Subiran HUMAN REPRODUCTION 32, 504-505, 2017 | | 2017 |