| Berberine reduces insulin resistance through protein kinase C–dependent up-regulation of insulin receptor expression WJ Kong, H Zhang, DQ Song, R Xue, W Zhao, J Wei, YM Wang, N Shan, ... Metabolism 58 (1), 109-119, 2009 | 333 | 2009 |
| Upregulated METTL3 promotes metastasis of colorectal Cancer via miR-1246/SPRED2/MAPK signaling pathway W Peng, J Li, R Chen, Q Gu, P Yang, W Qian, D Ji, Q Wang, Z Zhang, ... Journal of Experimental & Clinical Cancer Research 38, 1-16, 2019 | 280 | 2019 |
| p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis H Cha-Molstad, JE Yu, Z Feng, SH Lee, JG Kim, P Yang, B Han, KW Sung, ... Nature communications 8 (1), 102, 2017 | 199 | 2017 |
| Bioactivities of berberine metabolites after transformation through CYP450 isoenzymes Y Li, G Ren, YX Wang, WJ Kong, P Yang, YM Wang, YH Li, H Yi, ZR Li, ... Journal of translational medicine 9, 1-10, 2011 | 122 | 2011 |
| Berberine Analogues as a novel class of the low-density-lipoprotein receptor up-regulators: synthesis, structure− activity relationships, and cholesterol-lowering efficacy YH Li, P Yang, WJ Kong, YX Wang, CQ Hu, ZY Zuo, YM Wang, H Gao, ... Journal of Medicinal Chemistry 52 (2), 492-501, 2009 | 114 | 2009 |
| A quantitative chemical proteomics approach to profile the specific cellular targets of andrographolide, a promising anticancer agent that suppresses tumor metastasis J Wang, XF Tan, P Yang, J Zhou, M Gao, Z Li, TK Lim, Y He, CS Ong, ... Molecular & Cellular Proteomics 13 (3), 876-886, 2014 | 107 | 2014 |
| Modeling, molecular dynamics simulation, and mutation validation for structure of cannabinoid receptor 2 based on known crystal structures of GPCRs Z Feng, MH Alqarni, P Yang, Q Tong, A Chowdhury, L Wang, XQ Xie Journal of chemical information and modeling 54 (9), 2483-2499, 2014 | 106 | 2014 |
| Synthesis and structure–activity relationships of berberine analogues as a novel class of low-density-lipoprotein receptor up-regulators P Yang, DQ Song, YH Li, WJ Kong, YX Wang, LM Gao, SY Liu, RQ Cao, ... Bioorganic & medicinal chemistry letters 18 (16), 4675-4677, 2008 | 85 | 2008 |
| Selective inhibition of CDK4/6: a safe and effective strategy for developing anticancer drugs K Yuan, X Wang, H Dong, W Min, H Hao, P Yang Acta Pharmaceutica Sinica B, 2021 | 79 | 2021 |
| Structural insight into tetrameric hTRPV1 from homology modeling, molecular docking, molecular dynamics simulation, virtual screening, and bioassay validations Z Feng, LV Pearce, X Xu, X Yang, P Yang, PM Blumberg, XQ Xie Journal of chemical information and modeling 55 (3), 572-588, 2015 | 72 | 2015 |
| Latest advances in novel cannabinoid CB2 ligands for drug abuse and their therapeutic potential P Yang, L Wang, XQ Xie Future medicinal chemistry 4 (2), 187-204, 2012 | 65 | 2012 |
| Discovery of novel ligands for TNF-α and TNF receptor-1 through structure-based virtual screening and biological assay S Chen, Z Feng, Y Wang, S Ma, Z Hu, P Yang, Y Chai, X Xie Journal of chemical information and modeling 57 (5), 1101-1111, 2017 | 64 | 2017 |
| Design, synthesis, and cholesterol-lowering efficacy for prodrugs of berberrubine YH Li, Y Li, P Yang, WJ Kong, XF You, G Ren, HB Deng, YM Wang, ... Bioorganic & medicinal chemistry 18 (17), 6422-6428, 2010 | 63 | 2010 |
| Targeted inhibition of the type 2 cannabinoid receptor is a novel approach to reduce renal fibrosis L Zhou, S Zhou, P Yang, Y Tian, Z Feng, XQ Xie, Y Liu Kidney international 94 (4), 756-772, 2018 | 60 | 2018 |
| Lead Discovery, Chemistry Optimization, and Biological Evaluation Studies of Novel Biamide Derivatives as CB2 Receptor Inverse Agonists and Osteoclast Inhibitors P Yang, KZ Myint, Q Tong, R Feng, H Cao, AA Almehizia, MH Alqarni, ... Journal of medicinal chemistry 55 (22), 9973-9987, 2012 | 60 | 2012 |
| Small-molecule inhibitors targeting INK4 protein p18INK4C enhance ex vivo expansion of haematopoietic stem cells Y Gao, P Yang, H Shen, H Yu, X Song, L Zhang, P Zhang, H Cheng, Z Xie, ... Nature communications 6, 6328, 2015 | 56 | 2015 |
| Blocking the ZZ domain of sequestosome 1/p62 suppresses myeloma growth and osteoclast formation in vitro and induces dramatic bone formation in myeloma-bearing bones in vivo. J Teramachi, R Silbermann, P Yang, W Zhao, KS Mohammad, J Guo, ... Leukemia, 2015 | 52 | 2015 |
| Novel triaryl sulfonamide derivatives as selective cannabinoid receptor 2 inverse agonists and osteoclast inhibitors: discovery, optimization, and biological evaluation P Yang, L Wang, R Feng, AA Almehizia, Q Tong, KZ Myint, Q Ouyang, ... Journal of medicinal chemistry 56 (5), 2045-2058, 2013 | 50 | 2013 |
| TCONS_00012883 promotes proliferation and metastasis via DDX3/YY1/MMP1/PI3K‐AKT axis in colorectal cancer P Yang, J Li, C Peng, Y Tan, R Chen, W Peng, Q Gu, J Zhou, L Wang, ... Clinical and translational medicine 10 (6), e211, 2020 | 49 | 2020 |
| MicroRNA-1224-5p inhibits metastasis and epithelial-mesenchymal transition in colorectal cancer by targeting SP1-mediated NF-κB signaling pathways J Li, W Peng, P Yang, R Chen, Q Gu, W Qian, D Ji, Q Wang, Z Zhang, ... Frontiers in oncology 10, 294, 2020 | 45 | 2020 |
