| Biofilm formation mechanisms and targets for developing antibiofilm agents N Rabin, Y Zheng, C Opoku-Temeng, Y Du, E Bonsu, HO Sintim Future medicinal chemistry 7 (4), 493-512, 2015 | 770 | 2015 |
| Agents that inhibit bacterial biofilm formation N Rabin, Y Zheng, C Opoku-Temeng, Y Du, E Bonsu, HO Sintim Future medicinal chemistry 7 (5), 647-671, 2015 | 309 | 2015 |
| Cyclic dinucleotide (c-di-GMP, c-di-AMP, and cGAMP) signalings have come of age to be inhibited by small molecules C Opoku-Temeng, J Zhou, Y Zheng, J Su, HO Sintim Chemical communications 52 (60), 9327-9342, 2016 | 97 | 2016 |
| Klebsiella pneumoniae capsule polysaccharide as a target for therapeutics and vaccines C Opoku-Temeng, SD Kobayashi, FR DeLeo Computational and structural biotechnology journal 17, 1360-1366, 2019 | 87 | 2019 |
| Suramin potently inhibits cGAMP synthase, cGAS, in THP1 cells to modulate IFN-β levels M Wang, MA Sooreshjani, C Mikek, C Opoku-Temeng, HO Sintim Future Medicinal Chemistry 10 (11), 1301-1317, 2018 | 82 | 2018 |
| Inhibition of P. aeruginosa c-di-GMP phosphodiesterase RocR and swarming motility by a benzoisothiazolinone derivative Y Zheng, G Tsuji, C Opoku-Temeng, HO Sintim Chemical science 7 (9), 6238-6244, 2016 | 54 | 2016 |
| N-(1, 3, 4-oxadiazol-2-yl) benzamide analogs, bacteriostatic agents against methicillin-and vancomycin-resistant bacteria C Opoku-Temeng, GA Naclerio, H Mohammad, N Dayal, NS Abutaleb, ... European Journal of Medicinal Chemistry 155, 797-805, 2018 | 40 | 2018 |
| 3H-pyrazolo [4, 3-f] quinoline haspin kinase inhibitors and anticancer properties C Opoku-Temeng, N Dayal, MA Sooreshjani, HO Sintim Bioorganic chemistry 78, 418-426, 2018 | 39 | 2018 |
| Targeting c-di-GMP signaling, biofilm formation, and bacterial motility with small molecules C Opoku-Temeng, HO Sintim c-di-GMP Signaling: Methods and Protocols, 419-430, 2017 | 38 | 2017 |
| Inhibition of cyclic diadenylate cyclase, DisA, by polyphenols C Opoku-Temeng, HO Sintim Scientific Reports 6 (1), 25445, 2016 | 37 | 2016 |
| Proteomic analysis of bacterial response to a 4-hydroxybenzylidene indolinone compound, which re-sensitizes bacteria to traditional antibiotics C Opoku-Temeng, KI Onyedibe, UK Aryal, HO Sintim Journal of proteomics 202, 103368, 2019 | 36 | 2019 |
| Antibacterial Small Molecules That Potently Inhibit Staphylococcus aureus Lipoteichoic Acid Biosynthesis GA Naclerio, CW Karanja, C Opoku‐Temeng, HO Sintim ChemMedChem 14 (10), 1000-1004, 2019 | 27 | 2019 |
| Potent inhibition of cyclic diadenylate monophosphate cyclase by the antiparasitic drug, suramin C Opoku-Temeng, HO Sintim Chemical communications 52 (19), 3754-3757, 2016 | 27 | 2016 |
| Hydroxybenzylidene-indolinones, c-di-AMP synthase inhibitors, have antibacterial and anti-biofilm activities and also re-sensitize resistant bacteria to methicillin and vancomycin C Opoku-Temeng, N Dayal, J Miller, HO Sintim RSC advances 7 (14), 8288-8294, 2017 | 24 | 2017 |
| Dual FLT3/TOPK inhibitor with activity against FLT3-ITD secondary mutations potently inhibits acute myeloid leukemia cell lines N Dayal, C Opoku-Temeng, DE Hernandez, MA Sooreshjani, ... Future Medicinal Chemistry 10 (7), 823-835, 2018 | 21 | 2018 |
| Aminoisoquinoline benzamides, FLT3 and Src-family kinase inhibitors, potently inhibit proliferation of acute myeloid leukemia cell lines E Larocque, N Naganna, X Ma, C Opoku-Temeng, B Carter-Cooper, ... Future medicinal chemistry 9 (11), 1213-1225, 2017 | 19 | 2017 |
| Innate host defense against Klebsiella pneumoniae and the outlook for development of immunotherapies C Opoku-Temeng, N Malachowa, SD Kobayashi, FR DeLeo Journal of Innate Immunity 14 (3), 167-181, 2022 | 16 | 2022 |
| Alkynylnicotinamide‐Based Compounds as ABL1 Inhibitors with Potent Activities against Drug‐Resistant CML Harboring ABL1 (T315I) Mutant Kinase EA Larocque, N Naganna, C Opoku‐Temeng, AM Lambrecht, HO Sintim ChemMedChem 13 (12), 1172-1180, 2018 | 15 | 2018 |
| Geminal dihalogen isosteric replacement in hydrated AI-2 affords potent quorum sensing modulators M Guo, Y Zheng, JL Terell, M Ad, C Opoku-Temeng, WE Bentley, ... Chemical communications 51 (13), 2617-2620, 2015 | 15 | 2015 |
| Inhibitors of Intracellular Gram-Positive Bacterial Growth Synthesized via Povarov–Doebner Reactions N Dayal, C Opoku-Temeng, H Mohammad, NS Abutaleb, D Hernandez, ... ACS infectious diseases 5 (11), 1820-1830, 2019 | 14 | 2019 |
Herman O. SintimRichard B. Wetherill Distinguished Professor, Purdue UniversityVerified email at purdue.edu
