| Targeting bacterial membrane function: an underexploited mechanism for treating persistent infections JG Hurdle, AJ O'neill, I Chopra, RE Lee Nature Reviews Microbiology 9 (1), 62-75, 2011 | 841 | 2011 |
| Mycolactone: a polyketide toxin from Mycobacterium ulcerans required for virulence KM George, D Chatterjee, G Gunawardana, D Welty, J Hayman, R Lee, ... Science 283 (5403), 854-857, 1999 | 793 | 1999 |
| Mycolic acids: structure, biosynthesis and physiological functions CE Barry Iii, RE Lee, K Mdluli, AE Sampson, BG Schroeder, RA Slayden, ... Progress in lipid research 37 (2-3), 143-179, 1998 | 761 | 1998 |
| Validation of molecular docking programs for virtual screening against dihydropteroate synthase KE Hevener, W Zhao, DM Ball, K Babaoglu, J Qi, SW White, RE Lee Journal of chemical information and modeling 49 (2), 444-460, 2009 | 519 | 2009 |
| Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane AE Grzegorzewicz, H Pham, VAKB Gundi, MS Scherman, EJ North, ... Nature chemical biology 8 (4), 334-341, 2012 | 464 | 2012 |
| Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans TP Stinear, A Mve-Obiang, PLC Small, W Frigui, MJ Pryor, R Brosch, ... Proceedings of the National Academy of Sciences 101 (5), 1345-1349, 2004 | 449 | 2004 |
| Genome-Wide Expression Profiling of the Response to Azole, Polyene, Echinocandin, and Pyrimidine Antifungal Agents in Candida albicans TT Liu, REB Lee, KS Barker, RE Lee, L Wei, R Homayouni, PD Rogers Antimicrobial agents and chemotherapy 49 (6), 2226-2236, 2005 | 423 | 2005 |
| New agents for the treatment of drug-resistant Mycobacterium tuberculosis DT Hoagland, J Liu, RB Lee, RE Lee Advanced drug delivery reviews 102, 55-72, 2016 | 389 | 2016 |
| Combinatorial lead optimization of [1, 2]-diamines based on ethambutol as potential antituberculosis preclinical candidates RE Lee, M Protopopova, E Crooks, RA Slayden, M Terrot, CE Barry Journal of combinatorial chemistry 5 (2), 172-187, 2003 | 297 | 2003 |
| Identification of a gene involved in the biosynthesis of cyclopropanated mycolic acids in Mycobacterium tuberculosis. Y Yuan, RE Lee, GS Besra, JT Belisle, CE Barry 3rd Proceedings of the National Academy of Sciences 92 (14), 6630-6634, 1995 | 263 | 1995 |
| First Cultivation and Characterization of Mycobacterium ulcerans from the Environment F Portaels, WM Meyers, A Ablordey, AG Castro, K Chemlal, P de Rijk, ... PLoS neglected tropical diseases 2 (3), e178, 2008 | 251 | 2008 |
| Catalysis and sulfa drug resistance in dihydropteroate synthase MK Yun, Y Wu, Z Li, Y Zhao, MB Waddell, AM Ferreira, RE Lee, ... Science 335 (6072), 1110-1114, 2012 | 239 | 2012 |
| Novel insights into the mechanism of inhibition of MmpL3, a target of multiple pharmacophores in Mycobacterium tuberculosis W Li, A Upadhyay, FL Fontes, EJ North, Y Wang, DC Crans, ... Antimicrobial agents and chemotherapy 58 (11), 6413-6423, 2014 | 219 | 2014 |
| Heterogeneity of Mycolactones Produced by Clinical Isolates of Mycobacterium ulcerans: Implications for Virulence A Mve-Obiang, RE Lee, F Portaels, PLC Small Infection and immunity 71 (2), 774-783, 2003 | 211 | 2003 |
| Isoniazid affects multiple components of the type II fatty acid synthase system of Mycobacterium tuberculosis RA Slayden, RE Lee, CE Barry 3rd Molecular microbiology 38 (3), 514-525, 2000 | 209 | 2000 |
| Use of genomics and combinatorial chemistry in the development of new antimycobacterial drugs CE Barry III, RA Slayden, AE Sampson, RE Lee Biochemical pharmacology 59 (3), 221-231, 2000 | 202 | 2000 |
| Antimycobacterial action of thiolactomycin: an inhibitor of fatty acid and mycolic acid synthesis RA Slayden, RE Lee, JW Armour, AM Cooper, IM Orme, PJ Brennan, ... Antimicrobial agents and chemotherapy 40 (12), 2813-2819, 1996 | 199 | 1996 |
| Synthesis of the Arabinose Donor. beta.-D-Arabinofuranosyl-1-monophosphoryldecaprenol, development of a basic arabinosyl-transferase assay, and identification of ethambutol as … RE Lee, K Mikusova, PJ Brennan, GS Besra Journal of the American Chemical Society 117 (48), 11829-11832, 1995 | 194 | 1995 |
| Acyl-phosphates initiate membrane phospholipid synthesis in Gram-positive pathogens YJ Lu, YM Zhang, KD Grimes, J Qi, RE Lee, CO Rock Molecular cell 23 (5), 765-772, 2006 | 188 | 2006 |
| Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux RE Lee, JG Hurdle, J Liu, DF Bruhn, T Matt, MS Scherman, PK Vaddady, ... Nature medicine 20 (2), 152-158, 2014 | 184 | 2014 |
Bernd MeibohmDistinguished Professor of Pharmaceutical Sciences, University of TennesseeVerified email at uthsc.edu
