Malcolm Brenner
Malcolm Brenner
Professor of Medicine, Baylor College of Medicine
Verified email at
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Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta
EM Horwitz, DJ Prockop, LA Fitzpatrick, WWK Koo, PL Gordon, M Neel, ...
Nature medicine 5 (3), 309-313, 1999
A distinct “side population” of cells with high drug efflux capacity in human tumor cells
C Hirschmann-Jax, AE Foster, GG Wulf, JG Nuchtern, TW Jax, U Gobel, ...
Proceedings of the National Academy of Sciences 101 (39), 14228-14233, 2004
Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation
CM Rooney, CYC Ng, S Loftin, CA Smith, C Li, RA Krance, MK Brenner, ...
The Lancet 345 (8941), 9-13, 1995
Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus–induced lymphoma in allogeneic transplant recipients
CM Rooney, CA Smith, CYC Ng, SK Loftin, JW Sixbey, Y Gan, ...
Blood, The Journal of the American Society of Hematology 92 (5), 1549-1555, 1998
Inducible apoptosis as a safety switch for adoptive cell therapy
A Di Stasi, SK Tey, G Dotti, Y Fujita, A Kennedy-Nasser, C Martinez, ...
N Engl J Med 365, 1673-1683, 2011
Gene-marking to trace origin of relapse after autologous bone-marrow transplantation
MK Brenner, DR Rill, RA Krance, JN Ihle, RC Moen, J Mirro, WF Anderson
The Lancet 341 (8837), 85-86, 1993
Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma
MA Pule, B Savoldo, GD Myers, C Rossig, HV Russell, G Dotti, MH Huls, ...
Nature medicine 14 (11), 1264-1270, 2008
CD28 costimulation improves expansion and persistence of chimeric antigen receptor–modified T cells in lymphoma patients
B Savoldo, CA Ramos, E Liu, MP Mims, MJ Keating, G Carrum, ...
The Journal of clinical investigation 121 (5), 1822-1826, 2011
Long–term restoration of immunity against Epstein–Barr virus infection by adoptive transfer of gene–modified virus–specific T lymphocytes
HE Heslop, CYC Ng, C Li, CA Smith, SK Loftin, RA Krance, MK Brenner, ...
Nature medicine 2 (5), 551-555, 1996
Antitumor activity and long-term fate of chimeric antigen receptor–positive T cells in patients with neuroblastoma
CU Louis, B Savoldo, G Dotti, M Pule, E Yvon, GD Myers, C Rossig, ...
Blood, The Journal of the American Society of Hematology 118 (23), 6050-6056, 2011
Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfecta
EM Horwitz, DJ Prockop, PL Gordon, WWK Koo, LA Fitzpatrick, MD Neel, ...
Blood, The Journal of the American Society of Hematology 97 (5), 1227-1231, 2001
Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients
HE Heslop, KS Slobod, MA Pule, GA Hale, A Rousseau, CA Smith, ...
Blood, The Journal of the American Society of Hematology 115 (5), 925-935, 2010
Human epidermal growth factor receptor 2 (HER2)–specific chimeric antigen receptor–modified T cells for the immunotherapy of HER2-positive sarcoma
N Ahmed, VS Brawley, M Hegde, C Robertson, A Ghazi, C Gerken, E Liu, ...
Journal of clinical oncology 33 (15), 1688, 2015
An inducible caspase 9 safety switch for T-cell therapy
KC Straathof, MA Pule, P Yotnda, G Dotti, EF Vanin, MK Brenner, ...
Blood 105 (11), 4247-4254, 2005
Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals
AM Leen, GD Myers, U Sili, MH Huls, H Weiss, KS Leung, G Carrum, ...
Nature medicine 12 (10), 1160-1166, 2006
Direct demonstration that autologous bone marrow transplantation for solid tumors can return a multiplicity of tumorigenic cells
DR Rill, VM Santana, WM Roberts, T Nilson, LC Bowman, RA Krance, ...
Evidence for zanamivir resistance in an immunocompromised child infected with influenza B virus
LV Gubareva, MN Matrosovich, MK Brenner, RC Bethell, RG Webster
The Journal of infectious diseases 178 (5), 1257-1262, 1998
Gene marking to determine whether autologous marrow infusion restores long-term haemopoiesis in cancer patients
MK Brenner, VM Santana, DR Rill, MS Holladay, HE Heslop, M Buschle, ...
The Lancet 342 (8880), 1134-1137, 1993
Cytotoxic T Lymphocyte Therapy for Epstein-Barr Virus+ Hodgkin's Disease
CM Bollard, L Aguilar, KC Straathof, B Gahn, MH Huls, A Rousseau, ...
The Journal of experimental medicine 200 (12), 1623-1633, 2004
A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells
MA Pulè, KC Straathof, G Dotti, HE Heslop, CM Rooney, MK Brenner
Molecular Therapy 12 (5), 933-941, 2005
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