Irving Allen
Irving Allen
Virginia Tech, Virginia Maryland College of Veterinary Medicine, Department of Biomedical Sciences
Verified email at - Homepage
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The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA
IC Allen, MA Scull, CB Moore, EK Holl, E McElvania-TeKippe, DJ Taxman, ...
Immunity 30 (4), 556-565, 2009
The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
IC Allen, EME TeKippe, RMT Woodford, JM Uronis, EK Holl, AB Rogers, ...
Journal of Experimental Medicine 207 (5), 1045-1056, 2010
Natural, incidental, and engineered nanomaterials and their impacts on the Earth system
MF Hochella Jr, DW Mogk, J Ranville, IC Allen, GW Luther, LC Marr, ...
Science 363 (6434), eaau8299, 2019
NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling
IC Allen, JE Wilson, M Schneider, JD Lich, RA Roberts, JC Arthur, ...
Immunity 36 (5), 742-754, 2012
Staphylococcus aureus α-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells
RR Craven, X Gao, IC Allen, D Gris, JB Wardenburg, ...
PloS one 4 (10), e7446, 2009
NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways
IC Allen, CB Moore, M Schneider, Y Lei, BK Davis, MA Scull, D Gris, ...
Immunity 34 (6), 854-865, 2011
NLRP3 (NALP3, Cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and-independent pathways
SB Willingham, IC Allen, DT Bergstralh, WJ Brickey, MTH Huang, ...
The Journal of Immunology 183 (3), 2008-2015, 2009
The innate immune sensor NLRC3 attenuates Toll-like receptor signaling via modification of the signaling adaptor TRAF6 and transcription factor NF-κB
M Schneider, AG Zimmermann, RA Roberts, L Zhang, KV Swanson, ...
Nature immunology 13 (9), 823-831, 2012
Staphylococcus aureus α-Hemolysin Mediates Virulence in a Murine Model of Severe Pneumonia Through Activation of the NLRP3 Inflammasome
C Kebaier, RR Chamberland, IC Allen, X Gao, PM Broglie, JD Hall, ...
Journal of Infectious Diseases 205 (5), 807-817, 2012
TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection
J Segovia, A Sabbah, V Mgbemena, SY Tsai, TH Chang, MT Berton, ...
PloS one 7 (1), e29695, 2012
Granuloma Formation and Host Defense in Chronic Mycobacterium tuberculosis Infection Requires PYCARD/ASC but Not NLRP3 or Caspase-1
E McElvania TeKippe, IC Allen, PD Hulseberg, JT Sullivan, JR McCann, ...
PloS one 5 (8), e12320, 2010
High-frequency irreversible electroporation is an effective tumor ablation strategy that induces immunologic cell death and promotes systemic anti-tumor immunity
VM Ringel-Scaia, N Beitel-White, MF Lorenzo, RM Brock, KE Huie, ...
EBioMedicine 44, 112-125, 2019
The inflammasome component NLRP3 impairs antitumor vaccine by enhancing the accumulation of tumor-associated myeloid-derived suppressor cells
HW Van Deventer, JE Burgents, QP Wu, RMT Woodford, WJ Brickey, ...
Cancer research 70 (24), 10161-10169, 2010
Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity
JC Arthur, JD Lich, Z Ye, IC Allen, D Gris, JE Wilson, M Schneider, ...
The Journal of Immunology 185 (8), 4515-4519, 2010
Emerging roles for noncanonical NF-κB signaling in the modulation of inflammatory bowel disease pathobiology
DK McDaniel, K Eden, VM Ringel, IC Allen
Inflammatory bowel diseases 22 (9), 2265-2279, 2016
The NLRP1 inflammasome attenuates colitis and colitis-associated tumorigenesis
TM Williams, RA Leeth, DE Rothschild, SL Coutermarsh-Ott, DK McDaniel, ...
The Journal of Immunology 194 (7), 3369-3380, 2015
Nanoscale bacteria‐enabled autonomous drug delivery system (NanoBEADS) enhances intratumoral transport of nanomedicine
SB Suh, A Jo, MA Traore, Y Zhan, SL Coutermarsh‐Ott, VM Ringel‐Scaia, ...
Advanced Science 6 (3), 1801309, 2019
Beyond the inflammasome: regulatory NOD-like receptor modulation of the host immune response following virus exposure
S Coutermarsh-Ott, K Eden, IC Allen
Journal of General Virology 97 (4), 825-838, 2016
The pro-inflammatory chemokines CXCL9, CXCL10 and CXCL11 are upregulated following SARS-CoV-2 infection in an AKT-dependent manner
V Callahan, S Hawks, MA Crawford, CW Lehman, HA Morrison, ...
Viruses 13 (6), 1062, 2021
Photo-triggered release of 5-fluorouracil from a MOF drug delivery vehicle
KR Stefaniak, CC Epley, JJ Novak, ML McAndrew, HD Cornell, J Zhu, ...
Chemical communications 54 (55), 7617-7620, 2018
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