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Kashi Reddy Methuku
Kashi Reddy Methuku
Scientist-II, Alcami Corporation
Verified email at uwm.edu - Homepage
Title
Cited by
Cited by
Year
Synthesis and biological evaluation of 3, 5-diaryl isoxazoline/isoxazole linked 2, 3-dihydroquinazolinone hybrids as anticancer agents
A Kamal, EV Bharathi, JS Reddy, MJ Ramaiah, D Dastagiri, MK Reddy, ...
European Journal of Medicinal Chemistry 46 (2), 691-703, 2011
2262011
Remarkable enhancement in the DNA-binding ability of C2-fluoro substituted pyrrolo [2, 1-c][1, 4] benzodiazepines and their anticancer potential
A Kamal, DR Reddy, MK Reddy, G Balakishan, TB Shaik, M Chourasia, ...
Bioorganic & Medicinal Chemistry 17 (4), 1557-1572, 2009
1042009
2-Anilinonicotinyl linked 1, 3, 4-oxadiazole derivatives: Synthesis, antitumour activity and inhibition of tubulin polymerization
A Kamal, YVV Srikanth, TB Shaik, MNA Khan, M Ashraf, MK Reddy, ...
MedChemComm 2 (9), 819-823, 2011
802011
Synthesis and apoptosis inducing ability of new anilino substituted pyrimidine sulfonamides as potential anticancer agents
A Kamal, D Dastagiri, MJ Ramaiah, JS Reddy, EV Bharathi, MK Reddy, ...
European journal of medicinal chemistry 46 (12), 5817-5824, 2011
792011
Synthesis, anticancer activity and apoptosis inducing ability of bisindole linked pyrrolo [2, 1-c][1, 4] benzodiazepine conjugates
A Kamal, YVV Srikanth, MJ Ramaiah, MNA Khan, MK Reddy, M Ashraf, ...
Bioorganic & medicinal chemistry letters 22 (1), 571-578, 2012
632012
The design and development of imidazothiazole–chalcone derivatives as potential anticancer drugs
A Kamal, M Kashi Reddy, A Viswanath
Expert opinion on drug discovery 8 (3), 289-304, 2013
562013
Design, synthesis and biological evaluation of imidazopyridine/imidazopyrimidine-benzimidazole conjugates as potential anticancer agents
A Kamal, GB Kumar, VL Nayak, VS Reddy, AB Shaik, MK Reddy
MedChemComm 6 (4), 606-612, 2015
532015
Antinociceptive Effects of a Novel α2/α3-Subtype Selective GABAA Receptor Positive Allosteric Modulator
LA Lewter, JL Fisher, JN Siemian, KR Methuku, MM Poe, JM Cook, JX Li
ACS chemical neuroscience 8 (6), 1305-1312, 2017
482017
Synthesis and Characterization of a Novel γ-Aminobutyric Acid Type A (GABAA) Receptor Ligand That Combines Outstanding Metabolic Stability …
MM Poe, KR Methuku, G Li, AR Verma, KA Teske, DC Stafford, LA Arnold, ...
Journal of medicinal chemistry 59 (23), 10800-10806, 2016
442016
First in vivo testing of compounds targeting group 3 medulloblastomas using an implantable microdevice as a new paradigm for drug development
O Jonas, D Calligaris, KR Methuku, MM Poe, JP Francois, F Tranghese, ...
Journal of biomedical nanotechnology 12 (6), 1297-1302, 2016
422016
Synthesis and Biological Evaluation of Imidazopyridine–Oxindole Conjugates as Microtubule‐Targeting Agents
A Kamal, VS Reddy, S Karnewar, SS Chourasiya, AB Shaik, GB Kumar, ...
ChemMedChem 8 (12), 2015-2025, 2013
422013
Synthesis of terphenyl benzimidazoles as tubulin polymerization inhibitors
A Kamal, MK Reddy, TB Shaik, YVV Srikanth, VS Reddy, GB Kumar, ...
European journal of medicinal chemistry 50, 9-17, 2012
422012
Recent advances on structural modifications of benzothiazoles and their conjugate systems as potential chemotherapeutics
K Ahmed, S Yellamelli Valli Venkata, NAK Mohammed, F Sultana, ...
Expert Opinion on Investigational Drugs 21 (5), 619-635, 2012
362012
Bioisosteres of ethyl 8-ethynyl-6-(pyridin-2-yl)-4H-benzo [f] imidazo [1, 5-a][1, 4] diazepine-3-carboxylate (HZ-166) as novel alpha 2, 3 selective potentiators of GABAA …
JM Witkin, JL Smith, X Ping, SD Gleason, MM Poe, G Li, X Jin, J Hobbs, ...
Neuropharmacology 137, 332-343, 2018
342018
The α2, 3-selective potentiator of GABAA receptors, KRM-II-81, reduces nociceptive-associated behaviors induced by formalin and spinal nerve ligation in rats
JM Witkin, R Cerne, PG Davis, KB Freeman, JM Do Carmo, JK Rowlett, ...
Pharmacology Biochemistry and Behavior 180, 22-31, 2019
322019
Further evaluation of the potential anxiolytic activity of imidazo [1, 5-a][1, 4] diazepin agents selective for α2/3-containing GABAA receptors
JM Witkin, R Cerne, M Wakulchik, SD Gleason, TM Jones, G Li, LA Arnold, ...
Pharmacology Biochemistry and Behavior 157, 35-40, 2017
242017
Design and synthesis of aminostilbene–arylpropenones as tubulin polymerization inhibitors
A Kamal, GB Kumar, S Polepalli, AB Shaik, VS Reddy, MK Reddy, ...
ChemMedChem 9 (11), 2565-2579, 2014
212014
Synthesis of Aryl‐Substituted Naphthalene‐Linked Pyrrolobenzodiazepine Conjugates as Potential Anticancer Agents with Apoptosis‐Inducing Ability
A Kamal, MK Reddy, MJ Ramaiah, YVV Srikanth, Rajender, VS Reddy, ...
ChemMedChem 6 (9), 1665-1679, 2011
172011
Synthesis and biological evaluation of estradiol linked pyrrolo [2, 1-c][1, 4] benzodiazepine (PBD) conjugates as potential anticancer agents
A Kamal, MK Reddy, MJ Ramaiah, JS Reddy, YVV Srikanth, D Dastagiri, ...
Bioorganic & medicinal chemistry 19 (8), 2565-2581, 2011
162011
Synthesis and biological evaluation of anilino substituted pyrimidine linked pyrrolobenzodiazepines as potential anticancer agents
A Kamal, JS Reddy, MJ Ramaiah, EV Bharathi, D Dastagiri, MK Reddy, ...
Bioorganic & medicinal chemistry letters 20 (17), 5232-5236, 2010
162010
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