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Xiaoyu Xue
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Design of wide-spectrum inhibitors targeting coronavirus main proteases
H Yang, W Xie, X Xue, K Yang, J Ma, W Liang, Q Zhao, Z Zhou, D Pei, ...
PLoS biology 3 (10), e324, 2005
7492005
Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design
X Xue, H Yu, H Yang, F Xue, Z Wu, W Shen, J Li, Z Zhou, Y Ding, Q Zhao, ...
Journal of virology 82 (5), 2515-2527, 2008
4542008
Production of authentic SARS-CoV Mpro with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction
X Xue, H Yang, W Shen, Q Zhao, J Li, K Yang, C Chen, Y Jin, M Bartlam, ...
Journal of molecular biology 366 (3), 965-975, 2007
2422007
Chromatin‐bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death
H Jiang, X Xue, S Panda, A Kawale, RM Hooy, F Liang, J Sohn, P Sung, ...
The EMBO journal 38 (21), e102718, 2019
2052019
The Rad50 coiled-coil domain is indispensable for Mre11 complex functions
M Hohl, Y Kwon, SM Galván, X Xue, C Tous, A Aguilera, P Sung, ...
Nature structural & molecular biology 18 (10), 1124-1131, 2011
1112011
UAP56/DDX39B is a major cotranscriptional RNA–DNA helicase that unwinds harmful R loops genome-wide
C Pérez-Calero, A Bayona-Feliu, X Xue, SI Barroso, S Muñoz, ...
Genes & development 34 (13-14), 898-912, 2020
952020
Enhancement of BLM-DNA2-mediated long-range DNA end resection by CtIP
JM Daley, J Jimenez-Sainz, W Wang, AS Miller, X Xue, KA Nguyen, ...
Cell reports 21 (2), 324-332, 2017
882017
Smc5/6 mediated sumoylation of the Sgs1-Top3-Rmi1 complex promotes removal of recombination intermediates
JN Bonner, K Choi, X Xue, NP Torres, B Szakal, L Wei, B Wan, M Arter, ...
Cell reports 16 (2), 368-378, 2016
862016
Functions and regulation of the multitasking FANCM family of DNA motor proteins
X Xue, P Sung, X Zhao
Genes & Development 29 (17), 1777-1788, 2015
842015
Multifaceted role of the Topo IIIα–RMI1-RMI2 complex and DNA2 in the BLM-dependent pathway of DNA break end resection
JM Daley, T Chiba, X Xue, H Niu, P Sung
Nucleic acids research 42 (17), 11083-11091, 2014
792014
Restriction of replication fork regression activities by a conserved SMC complex
X Xue, K Choi, JN Bonner, T Chiba, Y Kwon, Y Xu, H Sanchez, C Wyman, ...
Molecular cell 56 (3), 436-445, 2014
762014
Rad51 presynaptic filament stabilization function of the mouse Swi5–Sfr1 heterodimeric complex
SP Tsai, GC Su, SW Lin, CI Chung, X Xue, MH Dunlop, Y Akamatsu, ...
Nucleic acids research 40 (14), 6558-6569, 2012
462012
A novel role of the Dna2 translocase function in DNA break resection
AS Miller, JM Daley, NT Pham, H Niu, X Xue, G Ira, P Sung
Genes & development 31 (5), 503-510, 2017
442017
Role of replication protein A in double holliday junction dissolution mediated by the BLM-Topo IIIα-RMI1-RMI2 protein complex
X Xue, S Raynard, V Busygina, AK Singh, P Sung
Journal of Biological Chemistry 288 (20), 14221-14227, 2013
442013
Structural insights into 5′ flap DNA unwinding and incision by the human FAN1 dimer
Q Zhao, X Xue, S Longerich, P Sung, Y Xiong
Nature communications 5 (1), 5726, 2014
412014
Rad5-dependent DNA repair functions of the Saccharomyces cerevisiae FANCM protein homolog Mph1
DL Daee, E Ferrari, S Longerich, X Zheng, X Xue, D Branzei, P Sung, ...
Journal of Biological Chemistry 287 (32), 26563-26575, 2012
392012
Single-molecule visualization of human BLM helicase as it acts upon double-and single-stranded DNA substrates
C Xue, JM Daley, X Xue, J Steinfeld, Y Kwon, P Sung, EC Greene
Nucleic acids research 47 (21), 11225-11237, 2019
362019
Structural insight into the Zika virus capsid encapsulating the viral genome
T Li, Q Zhao, X Yang, C Chen, K Yang, C Wu, T Zhang, Y Duan, X Xue, ...
Cell research 28 (4), 497-499, 2018
332018
Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions
JM Daley, N Tomimatsu, G Hooks, W Wang, AS Miller, X Xue, KA Nguyen, ...
Nature communications 11 (1), 3088, 2020
312020
A DNA nick at Ku-blocked double-strand break ends serves as an entry site for exonuclease 1 (Exo1) or Sgs1–Dna2 in long-range DNA end resection
W Wang, JM Daley, Y Kwon, X Xue, DS Krasner, AS Miller, KA Nguyen, ...
Journal of Biological Chemistry 293 (44), 17061-17069, 2018
312018
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