Design of wide-spectrum inhibitors targeting coronavirus main proteases H Yang, W Xie, X Xue, K Yang, J Ma, W Liang, Q Zhao, Z Zhou, D Pei, ... PLoS biology 3 (10), e324, 2005 | 749 | 2005 |
Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design X Xue, H Yu, H Yang, F Xue, Z Wu, W Shen, J Li, Z Zhou, Y Ding, Q Zhao, ... Journal of virology 82 (5), 2515-2527, 2008 | 454 | 2008 |
Production of authentic SARS-CoV Mpro with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction X Xue, H Yang, W Shen, Q Zhao, J Li, K Yang, C Chen, Y Jin, M Bartlam, ... Journal of molecular biology 366 (3), 965-975, 2007 | 242 | 2007 |
Chromatin‐bound cGAS is an inhibitor of DNA repair and hence accelerates genome destabilization and cell death H Jiang, X Xue, S Panda, A Kawale, RM Hooy, F Liang, J Sohn, P Sung, ... The EMBO journal 38 (21), e102718, 2019 | 205 | 2019 |
The Rad50 coiled-coil domain is indispensable for Mre11 complex functions M Hohl, Y Kwon, SM Galván, X Xue, C Tous, A Aguilera, P Sung, ... Nature structural & molecular biology 18 (10), 1124-1131, 2011 | 111 | 2011 |
UAP56/DDX39B is a major cotranscriptional RNA–DNA helicase that unwinds harmful R loops genome-wide C Pérez-Calero, A Bayona-Feliu, X Xue, SI Barroso, S Muñoz, ... Genes & development 34 (13-14), 898-912, 2020 | 95 | 2020 |
Enhancement of BLM-DNA2-mediated long-range DNA end resection by CtIP JM Daley, J Jimenez-Sainz, W Wang, AS Miller, X Xue, KA Nguyen, ... Cell reports 21 (2), 324-332, 2017 | 88 | 2017 |
Smc5/6 mediated sumoylation of the Sgs1-Top3-Rmi1 complex promotes removal of recombination intermediates JN Bonner, K Choi, X Xue, NP Torres, B Szakal, L Wei, B Wan, M Arter, ... Cell reports 16 (2), 368-378, 2016 | 86 | 2016 |
Functions and regulation of the multitasking FANCM family of DNA motor proteins X Xue, P Sung, X Zhao Genes & Development 29 (17), 1777-1788, 2015 | 84 | 2015 |
Multifaceted role of the Topo IIIα–RMI1-RMI2 complex and DNA2 in the BLM-dependent pathway of DNA break end resection JM Daley, T Chiba, X Xue, H Niu, P Sung Nucleic acids research 42 (17), 11083-11091, 2014 | 79 | 2014 |
Restriction of replication fork regression activities by a conserved SMC complex X Xue, K Choi, JN Bonner, T Chiba, Y Kwon, Y Xu, H Sanchez, C Wyman, ... Molecular cell 56 (3), 436-445, 2014 | 76 | 2014 |
Rad51 presynaptic filament stabilization function of the mouse Swi5–Sfr1 heterodimeric complex SP Tsai, GC Su, SW Lin, CI Chung, X Xue, MH Dunlop, Y Akamatsu, ... Nucleic acids research 40 (14), 6558-6569, 2012 | 46 | 2012 |
A novel role of the Dna2 translocase function in DNA break resection AS Miller, JM Daley, NT Pham, H Niu, X Xue, G Ira, P Sung Genes & development 31 (5), 503-510, 2017 | 44 | 2017 |
Role of replication protein A in double holliday junction dissolution mediated by the BLM-Topo IIIα-RMI1-RMI2 protein complex X Xue, S Raynard, V Busygina, AK Singh, P Sung Journal of Biological Chemistry 288 (20), 14221-14227, 2013 | 44 | 2013 |
Structural insights into 5′ flap DNA unwinding and incision by the human FAN1 dimer Q Zhao, X Xue, S Longerich, P Sung, Y Xiong Nature communications 5 (1), 5726, 2014 | 41 | 2014 |
Rad5-dependent DNA repair functions of the Saccharomyces cerevisiae FANCM protein homolog Mph1 DL Daee, E Ferrari, S Longerich, X Zheng, X Xue, D Branzei, P Sung, ... Journal of Biological Chemistry 287 (32), 26563-26575, 2012 | 39 | 2012 |
Single-molecule visualization of human BLM helicase as it acts upon double-and single-stranded DNA substrates C Xue, JM Daley, X Xue, J Steinfeld, Y Kwon, P Sung, EC Greene Nucleic acids research 47 (21), 11225-11237, 2019 | 36 | 2019 |
Structural insight into the Zika virus capsid encapsulating the viral genome T Li, Q Zhao, X Yang, C Chen, K Yang, C Wu, T Zhang, Y Duan, X Xue, ... Cell research 28 (4), 497-499, 2018 | 33 | 2018 |
Specificity of end resection pathways for double-strand break regions containing ribonucleotides and base lesions JM Daley, N Tomimatsu, G Hooks, W Wang, AS Miller, X Xue, KA Nguyen, ... Nature communications 11 (1), 3088, 2020 | 31 | 2020 |
A DNA nick at Ku-blocked double-strand break ends serves as an entry site for exonuclease 1 (Exo1) or Sgs1–Dna2 in long-range DNA end resection W Wang, JM Daley, Y Kwon, X Xue, DS Krasner, AS Miller, KA Nguyen, ... Journal of Biological Chemistry 293 (44), 17061-17069, 2018 | 31 | 2018 |