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Lior Zimmerman
Lior Zimmerman
Enzymit Inc
Verified email at mail.huji.ac.il
Title
Cited by
Cited by
Year
Macromolecular modeling and design in Rosetta: recent methods and frameworks
JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ...
Nature methods 17 (7), 665-680, 2020
5502020
Rosetta FlexPepDock ab-initio: simultaneous folding, docking and refinement of peptides onto their receptors
B Raveh, N London, L Zimmerman, O Schueler-Furman
PloS one 6 (4), e18934, 2011
3002011
Structure-based identification of HDAC8 non-histone substrates
N Alam, L Zimmerman, NA Wolfson, CG Joseph, CA Fierke, ...
Structure 24 (3), 458-468, 2016
572016
A novel system for functional determination of variants of uncertain significance using deep convolutional neural networks
L Zimmerman, O Zelichov, A Aizenmann, Z Barbash, M Vidne, G Tarcic
Scientific Reports 10 (1), 4192, 2020
52020
A systematic analysis of BRAF mutations and their sensitivity to different BRAF inhibitors
Z Barbash, D Haham, L Hafzadi, R Zipor, S Barth, A Aizenman, ...
Cancer Research 80 (16_Supplement), 1092-1092, 2020
12020
Project plan generation from an information architecture model
BP Byrne, H Marchant, L Zimmerman
US Patent 10,346,776, 2019
12019
Context-dependent design of induced-fit enzymes using deep learning generates well-expressed, thermally stable and active enzymes
L Zimmerman, N Alon, I Levin, A Koganitsky, N Shpigel, C Brestel, ...
Proceedings of the National Academy of Sciences 121 (11), e2313809121, 2024
2024
Performance upgrade of a microbial explosives’ sensor strain by screening a high throughput saturation library of a transcriptional regulator
L David, E Shpigel, I Levin, S Moshe, L Zimmerman, S Dadon-Simanowitz, ...
Computational and Structural Biotechnology Journal 21, 4252-4260, 2023
2023
System and method for generating antibody libraries
L Zimmerman, D Baran
US Patent App. 17/163,989, 2021
2021
Computational pipeline for antibody modeling and design
D Baran, L Zimmerman
US Patent 11,127,483, 2021
2021
Pross optimized enzymes
L Zimmerman, D Baran
US Patent App. 16/646,298, 2020
2020
Pross optimized enzymes
L Zimmerman, D Baran
US Patent App. 16/629,372, 2020
2020
Anti-vegf antibody
D Baran, L Zimmerman
US Patent App. 16/646,093, 2020
2020
Computational affinity maturation of antibody libraries using sequence enumeration
L Zimmerman
US Patent App. 16/656,113, 2020
2020
Anti-pd-1 scfvs
D Baran, L Zimmerman
US Patent App. 16/242,417, 2019
2019
Accurate prediction of the signaling pathway activity elicited by variants of uncertain significance (VUS) and their drug sensitivity using deep convolutional neural networks …
L Zimmerman, A Aizenman, Y Daitsh, Z Barbash, G Tarcic, M Vidne
Cancer Research 79 (13_Supplement), 2447-2447, 2019
2019
Project plan generation from an information architecture model
BP Byrne, H Marchant, L Zimmerman
US Patent 10,318,906, 2019
2019
Mapping the activation landscape of the MAPK\ERK pathway for variants of unknown significance (VUS) using convolutional neural networks (CNN).
G Tarcic, L Zimmerman, A Aizenman, Z Barbash, O Zelichov, M Vidne
Journal of Clinical Oncology 37 (15_suppl), e14615-e14615, 2019
2019
System and method for generating antibody libraries
L Zimmerman, D Baran
US Patent App. 15/863,927, 2018
2018
Computational methods for designing polypeptide libraries
L Zimmerman
US Patent App. 15/685,611, 2018
2018
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