|Dysregulated bioenergetics: a key regulator of joint inflammation|
M Biniecka, M Canavan, T McGarry, W Gao, J McCormick, S Cregan, ...
Annals of the rheumatic diseases 75 (12), 2192-2200, 2016
|Altered mitochondrial function and energy metabolism is associated with a radioresistant phenotype in oesophageal adenocarcinoma|
N Lynam-Lennon, SG Maher, A Maguire, J Phelan, C Muldoon, ...
PloS one 9 (6), e100738, 2014
|The role of inflammation in cancer of the esophagus|
KE O’Sullivan, JJ Phelan, C O’Hanlon, J Lysaght, JN O’Sullivan, ...
Expert review of gastroenterology & hepatology 8 (7), 749-760, 2014
|Mucosal-associated invariant T cells display diminished effector capacity in oesophageal adenocarcinoma|
AM Melo, AM O'Brien, JJ Phelan, SA Kennedy, NAW Wood, N Veerapen, ...
Frontiers in immunology 10, 1580, 2019
|Targeting bioenergetics prevents CD4 T cell–mediated activation of synovial fibroblasts in rheumatoid arthritis|
A Petrasca, JJ Phelan, S Ansboro, DJ Veale, U Fearon, JM Fletcher
Rheumatology 59 (10), 2816-2828, 2020
|Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival|
CM Dowling, J Phelan, JA Callender, MC Cathcart, B Mehigan, ...
Oncotarget 7 (15), 20919, 2016
|Expression of protein kinase C gamma promotes cell migration in colon cancer|
CM Dowling, SL Hayes, JJ Phelan, MC Cathcart, SP Finn, B Mehigan, ...
Oncotarget 8 (42), 72096, 2017
|Desferrioxamine Supports Metabolic Function in Primary Human Macrophages Infected With Mycobacterium tuberculosis|
JJ Phelan, K McQuaid, C Kenny, KM Gogan, DJ Cox, SA Basdeo, ...
Frontiers in immunology 11, 836, 2020
|Differential expression of mitochondrial energy metabolism profiles across the metaplasia–dysplasia–adenocarcinoma disease sequence in Barrett's oesophagus|
JJ Phelan, F MacCarthy, R Feighery, NJ O'Farrell, N Lynam-Lennon, ...
Cancer letters 354 (1), 122-131, 2014
|Trained immunity is induced in humans after immunization with an adenoviral vector COVID-19 vaccine|
DM Murphy, DJ Cox, SA Connolly, EP Breen, AAI Brugman, JJ Phelan, ...
The Journal of Clinical Investigation 133 (2), 2023
|Inhibiting histone deacetylases in human macrophages promotes glycolysis, IL-1β, and T helper cell responses to Mycobacterium tuberculosis|
DJ Cox, AM Coleman, KM Gogan, JJ Phelan, C Ó Maoldomhnaigh, ...
Frontiers in Immunology, 1609, 2020
|Modulating iron for metabolic support of TB host defense|
JJ Phelan, SA Basdeo, SC Tazoll, S McGivern, JR Saborido, J Keane
Frontiers in Immunology 9, 2296, 2018
|Characterising the prognostic potential of HLA-DR during colorectal cancer development|
MR Dunne, JJ Phelan, AJ Michielsen, AA Maguire, C Dunne, P Martin, ...
Cancer Immunology, Immunotherapy 69, 1577-1588, 2020
|Differential expression profiles of oxidative stress levels, 8-oxo-dG and 4-HNE, in barrett’s esophagus compared to esophageal adenocarcinoma|
NJ O’Farrell, JJ Phelan, R Feighery, B Doyle, SL Picardo, N Ravi, ...
International Journal of Molecular Sciences 20 (18), 4449, 2019
|Linking circulating serum proteins with clinical outcomes in esophageal adenocarcinoma—an emerging role for chemokines|
NE Donlon, A Sheppard, M Davern, F O’Connell, JJ Phelan, R Power, ...
Cancers 12 (11), 3356, 2020
|Understanding and exploiting the effect of tuberculosis antimicrobials on host mitochondrial function and bioenergetics|
C Cahill, JJ Phelan, J Keane
Frontiers in Cellular and Infection Microbiology, 493, 2020
|Changes in mitochondrial stability during the progression of the Barrett’s esophagus disease sequence|
NJ O’Farrell, R Feighery, SL Picardo, N Lynam-Lennon, M Biniecka, ...
BMC cancer 16, 1-9, 2016
|Lactate alters metabolism in human macrophages and improves their ability to kill mycobacterium tuberculosis|
C Ó Maoldomhnaigh, DJ Cox, JJ Phelan, M Mitermite, DM Murphy, ...
Frontiers in Immunology 12, 663695, 2021
|The Warburg Effect Occurs Rapidly in Stimulated Human Adult but Not Umbilical Cord Blood Derived Macrophages|
C Ó Maoldomhnaigh, DJ Cox, JJ Phelan, FD Malone, J Keane, ...
Frontiers in Immunology 12, 657261, 2021
|Characterizing caspase-1 involvement during esophageal disease progression|
G Barber, A Anand, K Oficjalska, JJ Phelan, AB Heeran, E Flis, NE Clarke, ...
Cancer Immunology, Immunotherapy 69, 2635-2649, 2020