James J. Phelan
James J. Phelan
Biomedical Research Scientist
Verified email at - Homepage
Cited by
Cited by
Dysregulated bioenergetics: a key regulator of joint inflammation
M Biniecka, M Canavan, T McGarry, W Gao, J McCormick, S Cregan, ...
Annals of the rheumatic diseases 75 (12), 2192-2200, 2016
Altered mitochondrial function and energy metabolism is associated with a radioresistant phenotype in oesophageal adenocarcinoma
N Lynam-Lennon, SG Maher, A Maguire, J Phelan, C Muldoon, ...
PloS one 9 (6), e100738, 2014
The role of inflammation in cancer of the esophagus
KE O’Sullivan, JJ Phelan, C O’Hanlon, J Lysaght, JN O’Sullivan, ...
Expert review of gastroenterology & hepatology 8 (7), 749-760, 2014
Mucosal-associated invariant T cells display diminished effector capacity in oesophageal adenocarcinoma
AM Melo, AM O'Brien, JJ Phelan, SA Kennedy, NAW Wood, N Veerapen, ...
Frontiers in immunology 10, 1580, 2019
Targeting bioenergetics prevents CD4 T cell–mediated activation of synovial fibroblasts in rheumatoid arthritis
A Petrasca, JJ Phelan, S Ansboro, DJ Veale, U Fearon, JM Fletcher
Rheumatology 59 (10), 2816-2828, 2020
Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival
CM Dowling, J Phelan, JA Callender, MC Cathcart, B Mehigan, ...
Oncotarget 7 (15), 20919, 2016
Expression of protein kinase C gamma promotes cell migration in colon cancer
CM Dowling, SL Hayes, JJ Phelan, MC Cathcart, SP Finn, B Mehigan, ...
Oncotarget 8 (42), 72096, 2017
Desferrioxamine Supports Metabolic Function in Primary Human Macrophages Infected With Mycobacterium tuberculosis
JJ Phelan, K McQuaid, C Kenny, KM Gogan, DJ Cox, SA Basdeo, ...
Frontiers in immunology 11, 836, 2020
Differential expression of mitochondrial energy metabolism profiles across the metaplasia–dysplasia–adenocarcinoma disease sequence in Barrett's oesophagus
JJ Phelan, F MacCarthy, R Feighery, NJ O'Farrell, N Lynam-Lennon, ...
Cancer letters 354 (1), 122-131, 2014
Trained immunity is induced in humans after immunization with an adenoviral vector COVID-19 vaccine
DM Murphy, DJ Cox, SA Connolly, EP Breen, AAI Brugman, JJ Phelan, ...
The Journal of Clinical Investigation 133 (2), 2023
Inhibiting histone deacetylases in human macrophages promotes glycolysis, IL-1β, and T helper cell responses to Mycobacterium tuberculosis
DJ Cox, AM Coleman, KM Gogan, JJ Phelan, C Maoldomhnaigh, ...
Frontiers in Immunology, 1609, 2020
Modulating iron for metabolic support of TB host defense
JJ Phelan, SA Basdeo, SC Tazoll, S McGivern, JR Saborido, J Keane
Frontiers in Immunology 9, 2296, 2018
Characterising the prognostic potential of HLA-DR during colorectal cancer development
MR Dunne, JJ Phelan, AJ Michielsen, AA Maguire, C Dunne, P Martin, ...
Cancer Immunology, Immunotherapy 69, 1577-1588, 2020
Differential expression profiles of oxidative stress levels, 8-oxo-dG and 4-HNE, in barrett’s esophagus compared to esophageal adenocarcinoma
NJ O’Farrell, JJ Phelan, R Feighery, B Doyle, SL Picardo, N Ravi, ...
International Journal of Molecular Sciences 20 (18), 4449, 2019
Linking circulating serum proteins with clinical outcomes in esophageal adenocarcinoma—an emerging role for chemokines
NE Donlon, A Sheppard, M Davern, F O’Connell, JJ Phelan, R Power, ...
Cancers 12 (11), 3356, 2020
Understanding and exploiting the effect of tuberculosis antimicrobials on host mitochondrial function and bioenergetics
C Cahill, JJ Phelan, J Keane
Frontiers in Cellular and Infection Microbiology, 493, 2020
Changes in mitochondrial stability during the progression of the Barrett’s esophagus disease sequence
NJ O’Farrell, R Feighery, SL Picardo, N Lynam-Lennon, M Biniecka, ...
BMC cancer 16, 1-9, 2016
Lactate alters metabolism in human macrophages and improves their ability to kill mycobacterium tuberculosis
C Maoldomhnaigh, DJ Cox, JJ Phelan, M Mitermite, DM Murphy, ...
Frontiers in Immunology 12, 663695, 2021
The Warburg Effect Occurs Rapidly in Stimulated Human Adult but Not Umbilical Cord Blood Derived Macrophages
C Maoldomhnaigh, DJ Cox, JJ Phelan, FD Malone, J Keane, ...
Frontiers in Immunology 12, 657261, 2021
Characterizing caspase-1 involvement during esophageal disease progression
G Barber, A Anand, K Oficjalska, JJ Phelan, AB Heeran, E Flis, NE Clarke, ...
Cancer Immunology, Immunotherapy 69, 2635-2649, 2020
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