Dysregulated bioenergetics: a key regulator of joint inflammation M Biniecka, M Canavan, T McGarry, W Gao, J McCormick, S Cregan, ... Annals of the rheumatic diseases 75 (12), 2192-2200, 2016 | 185 | 2016 |
Altered mitochondrial function and energy metabolism is associated with a radioresistant phenotype in oesophageal adenocarcinoma N Lynam-Lennon, SG Maher, A Maguire, J Phelan, C Muldoon, ... PloS one 9 (6), e100738, 2014 | 86 | 2014 |
The role of inflammation in cancer of the esophagus KE O’Sullivan, JJ Phelan, C O’Hanlon, J Lysaght, JN O’Sullivan, ... Expert review of gastroenterology & hepatology 8 (7), 749-760, 2014 | 65 | 2014 |
Mucosal-associated invariant T cells display diminished effector capacity in oesophageal adenocarcinoma AM Melo, AM O'Brien, JJ Phelan, SA Kennedy, NAW Wood, N Veerapen, ... Frontiers in immunology 10, 1580, 2019 | 47 | 2019 |
Targeting bioenergetics prevents CD4 T cell–mediated activation of synovial fibroblasts in rheumatoid arthritis A Petrasca, JJ Phelan, S Ansboro, DJ Veale, U Fearon, JM Fletcher Rheumatology 59 (10), 2816-2828, 2020 | 44 | 2020 |
Protein kinase C beta II suppresses colorectal cancer by regulating IGF-1 mediated cell survival CM Dowling, J Phelan, JA Callender, MC Cathcart, B Mehigan, ... Oncotarget 7 (15), 20919, 2016 | 40 | 2016 |
Expression of protein kinase C gamma promotes cell migration in colon cancer CM Dowling, SL Hayes, JJ Phelan, MC Cathcart, SP Finn, B Mehigan, ... Oncotarget 8 (42), 72096, 2017 | 33 | 2017 |
Desferrioxamine Supports Metabolic Function in Primary Human Macrophages Infected With Mycobacterium tuberculosis JJ Phelan, K McQuaid, C Kenny, KM Gogan, DJ Cox, SA Basdeo, ... Frontiers in immunology 11, 836, 2020 | 31 | 2020 |
Differential expression of mitochondrial energy metabolism profiles across the metaplasia–dysplasia–adenocarcinoma disease sequence in Barrett's oesophagus JJ Phelan, F MacCarthy, R Feighery, NJ O'Farrell, N Lynam-Lennon, ... Cancer letters 354 (1), 122-131, 2014 | 30 | 2014 |
Trained immunity is induced in humans after immunization with an adenoviral vector COVID-19 vaccine DM Murphy, DJ Cox, SA Connolly, EP Breen, AAI Brugman, JJ Phelan, ... The Journal of Clinical Investigation 133 (2), 2023 | 28 | 2023 |
Inhibiting histone deacetylases in human macrophages promotes glycolysis, IL-1β, and T helper cell responses to Mycobacterium tuberculosis DJ Cox, AM Coleman, KM Gogan, JJ Phelan, C Ó Maoldomhnaigh, ... Frontiers in Immunology, 1609, 2020 | 27 | 2020 |
Modulating iron for metabolic support of TB host defense JJ Phelan, SA Basdeo, SC Tazoll, S McGivern, JR Saborido, J Keane Frontiers in Immunology 9, 2296, 2018 | 27 | 2018 |
Characterising the prognostic potential of HLA-DR during colorectal cancer development MR Dunne, JJ Phelan, AJ Michielsen, AA Maguire, C Dunne, P Martin, ... Cancer Immunology, Immunotherapy 69, 1577-1588, 2020 | 21 | 2020 |
Differential expression profiles of oxidative stress levels, 8-oxo-dG and 4-HNE, in barrett’s esophagus compared to esophageal adenocarcinoma NJ O’Farrell, JJ Phelan, R Feighery, B Doyle, SL Picardo, N Ravi, ... International Journal of Molecular Sciences 20 (18), 4449, 2019 | 20 | 2019 |
Linking circulating serum proteins with clinical outcomes in esophageal adenocarcinoma—an emerging role for chemokines NE Donlon, A Sheppard, M Davern, F O’Connell, JJ Phelan, R Power, ... Cancers 12 (11), 3356, 2020 | 17 | 2020 |
Understanding and exploiting the effect of tuberculosis antimicrobials on host mitochondrial function and bioenergetics C Cahill, JJ Phelan, J Keane Frontiers in Cellular and Infection Microbiology, 493, 2020 | 14 | 2020 |
Changes in mitochondrial stability during the progression of the Barrett’s esophagus disease sequence NJ O’Farrell, R Feighery, SL Picardo, N Lynam-Lennon, M Biniecka, ... BMC cancer 16, 1-9, 2016 | 14 | 2016 |
Lactate alters metabolism in human macrophages and improves their ability to kill mycobacterium tuberculosis C Ó Maoldomhnaigh, DJ Cox, JJ Phelan, M Mitermite, DM Murphy, ... Frontiers in Immunology 12, 663695, 2021 | 13 | 2021 |
The Warburg Effect Occurs Rapidly in Stimulated Human Adult but Not Umbilical Cord Blood Derived Macrophages C Ó Maoldomhnaigh, DJ Cox, JJ Phelan, FD Malone, J Keane, ... Frontiers in Immunology 12, 657261, 2021 | 13 | 2021 |
Characterizing caspase-1 involvement during esophageal disease progression G Barber, A Anand, K Oficjalska, JJ Phelan, AB Heeran, E Flis, NE Clarke, ... Cancer Immunology, Immunotherapy 69, 2635-2649, 2020 | 13 | 2020 |