| Covalent modification at Cys151 dissociates the electrophile sensor Keap1 from the ubiquitin ligase CUL3 G Rachakonda, Y Xiong, KR Sekhar, SL Stamer, DC Liebler, ML Freeman Chemical research in toxicology 21 (3), 705-710, 2008 | 239 | 2008 |
| Cysteine-based regulation of the CUL3 adaptor protein Keap1 KR Sekhar, G Rachakonda, ML Freeman Toxicology and applied pharmacology 244 (1), 21-26, 2010 | 192 | 2010 |
| Activating transcription factor 3 is a novel repressor of the nuclear factor erythroid-derived 2–related factor 2 (Nrf2)–regulated stress pathway SL Brown, KR Sekhar, G Rachakonda, S Sasi, ML Freeman Cancer research 68 (2), 364-368, 2008 | 124 | 2008 |
| Smad7 induces hepatic metastasis in colorectal cancer SK Halder, G Rachakonda, NG Deane, PK Datta British journal of cancer 99 (6), 957-965, 2008 | 110 | 2008 |
| Increased cell migration and plasticity in Nrf2-deficient cancer cell lines G Rachakonda, KR Sekhar, D Jowhar, PC Samson, JP Wikswo, ... Oncogene 29 (25), 3703-3714, 2010 | 106 | 2010 |
| Cardiological Society of India: position statement for the management of ST elevation myocardial infarction in India S Guha, R Sethi, S Ray, VK Bahl, S Shanmugasundaram, P Kerkar, ... Indian heart journal 69 (Suppl 1), S63, 2017 | 77 | 2017 |
| NRF2 deficiency reduces life span of mice administered thoracic irradiation EL Travis, G Rachakonda, X Zhou, K Korhonen, KR Sekhar, S Biswas, ... Free Radical Biology and Medicine 51 (6), 1175-1183, 2011 | 77 | 2011 |
| Foodborne outbreak caused by a Norwalk‐like virus in India R Girish, S Broor, L Dar, D Ghosh Journal of medical virology 67 (4), 603-607, 2002 | 75 | 2002 |
| Advances in preclinical approaches to Chagas disease drug discovery F Villalta, G Rachakonda Expert opinion on drug discovery 14 (11), 1161-1174, 2019 | 71 | 2019 |
| VFV as a new effective CYP51 structure-derived drug candidate for Chagas disease and visceral leishmaniasis GI Lepesheva, TY Hargrove, G Rachakonda, Z Wawrzak, S Pomel, ... The Journal of infectious diseases 212 (9), 1439-1448, 2015 | 67 | 2015 |
| Crystal structure of the new investigational drug candidate VT-1598 in complex with Aspergillus fumigatus sterol 14α-demethylase provides insights into its broad-spectrum … TY Hargrove, EP Garvey, WJ Hoekstra, CM Yates, Z Wawrzak, ... Antimicrobial agents and chemotherapy 61 (7), 10.1128/aac. 00570-17, 2017 | 66 | 2017 |
| Transforming growth factor beta in hepatitis C virus infection: In vivo and in vitro findings S Ray, SL Broor, Y Vaishnav, C Sarkar, R Girish, L Dar, P Seth, S Broor Journal of gastroenterology and hepatology 18 (4), 393-403, 2003 | 65 | 2003 |
| Clinical Candidate VT-1161's Antiparasitic Effect In Vitro, Activity in a Murine Model of Chagas Disease, and Structural Characterization in Complex with the Target … WJ Hoekstra, TY Hargrove, Z Wawrzak, D da Gama Jaen Batista, ... Antimicrobial agents and chemotherapy 60 (2), 1058-1066, 2016 | 49 | 2016 |
| Structural Basis for Rational Design of Inhibitors Targeting Trypanosoma cruzi Sterol 14α-Demethylase: Two Regions of the Enzyme Molecule Potentiate Its Inhibition L Friggeri, TY Hargrove, G Rachakonda, AD Williams, Z Wawrzak, ... Journal of medicinal chemistry 57 (15), 6704-6717, 2014 | 49 | 2014 |
| Early Regulation of Profibrotic Genes in Primary Human Cardiac Myocytes by Trypanosoma cruzi AN Udoko, CA Johnson, A Dykan, G Rachakonda, F Villalta, SN Mandape, ... PLoS neglected tropical diseases 10 (1), e0003747, 2016 | 45 | 2016 |
| Genetic diversity of noroviruses and sapoviruses in children with acute sporadic gastroenteritis in New Delhi, India G Rachakonda, A Choudekar, S Parveen, S Bhatnagar, A Patwari, ... Journal of Clinical Virology 43 (1), 42-48, 2008 | 40 | 2008 |
| Sterol 14α-Demethylase Structure-Based Design of VNI ((R)-N-(1-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-yl)ethyl)-4-(5-phenyl-1,3,4-oxadiazol-2-yl)benzamide … L Friggeri, TY Hargrove, Z Wawrzak, AL Blobaum, G Rachakonda, ... Journal of medicinal chemistry 61 (13), 5679-5691, 2018 | 37 | 2018 |
| The novel chemical entity YTR107 inhibits recruitment of nucleophosmin to sites of DNA damage, suppressing repair of DNA double-strand breaks and enhancing radiosensitization KR Sekhar, YT Reddy, PN Reddy, PA Crooks, A Venkateswaran, ... Clinical Cancer Research 17 (20), 6490-6499, 2011 | 32 | 2011 |
| piRNAs as modulators of disease pathogenesis KJ Rayford, A Cooley, JT Rumph, A Arun, G Rachakonda, F Villalta, ... International Journal of Molecular Sciences 22 (5), 2373, 2021 | 31 | 2021 |
| Sterol 14α-demethylase structure-based optimization of drug candidates for human infections with the protozoan Trypanosomatidae L Friggeri, TY Hargrove, G Rachakonda, AL Blobaum, P Fisher, ... Journal of medicinal chemistry 61 (23), 10910-10921, 2018 | 25 | 2018 |
Sekhar KonjetiVanderbilt universityVerified email at vanderbilt.edu
