| Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model TF Rogers, F Zhao, D Huang, N Beutler, A Burns, W He, O Limbo, C Smith, ... Science 369 (6506), 956-963, 2020 | 1338 | 2020 |
| SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase Q Zheng, JL Woehl, S Kitamura, D Santos-Martins, CJ Smedley, G Li, ... Proceedings of the National Academy of Sciences 116 (38), 18808-18814, 2019 | 143 | 2019 |
| Sulfur (VI) fluoride exchange (SuFEx)-enabled high-throughput medicinal chemistry S Kitamura, Q Zheng, JL Woehl, A Solania, E Chen, N Dillon, MV Hull, ... Journal of the American Chemical Society 142 (25), 10899-10904, 2020 | 109 | 2020 |
| The extracellular adherence protein from Staphylococcus aureus inhibits the classical and lectin pathways of complement by blocking formation of the C3 proconvertase JL Woehl, DAC Stapels, BL Garcia, KX Ramyar, A Keightley, M Ruyken, ... The journal of immunology 193 (12), 6161-6171, 2014 | 73 | 2014 |
| An influenza A hemagglutinin small-molecule fusion inhibitor identified by a new high-throughput fluorescence polarization screen Y Yao, RU Kadam, CCD Lee, JL Woehl, NC Wu, X Zhu, S Kitamura, ... Proceedings of the National Academy of Sciences 117 (31), 18431-18438, 2020 | 31 | 2020 |
| Sialic acid ligands of CD28 suppress costimulation of T cells LJ Edgar, AJ Thompson, VF Vartabedian, C Kikuchi, JL Woehl, JR Teijaro, ... ACS central science 7 (9), 1508-1515, 2021 | 28 | 2021 |
| The structural basis for inhibition of the classical and lectin complement pathways by S. aureus extracellular adherence protein JL Woehl, KX Ramyar, BB Katz, JK Walker, BV Geisbrecht Protein Science 26 (8), 1595-1608, 2017 | 17 | 2017 |
| Evidence for multiple modes of neutrophil serine protease recognition by the EAP family of Staphylococcal innate immune evasion proteins DAC Stapels, JL Woehl, FJ Milder, AT Tromp, AA van Batenburg, ... Protein Science 27 (2), 509-522, 2018 | 16 | 2018 |
| Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors Y Cheng, G Li, CJ Smedley, MC Giel, S Kitamura, JL Woehl, G Bianco, ... Proceedings of the National Academy of Sciences 119 (37), e2208540119, 2022 | 13 | 2022 |
| 1H, 15N, and 13C resonance assignments of Staphylococcus aureus extracellular adherence protein domain 4 JL Woehl, D Takahashi, AI Herrera, BV Geisbrecht, O Prakash Biomolecular NMR assignments 10, 301-305, 2016 | 13 | 2016 |
| Identification of peptidic inhibitors of the alternative complement pathway based on Staphylococcus aureus SCIN proteins BJ Summers, BL Garcia, JL Woehl, KX Ramyar, X Yao, BV Geisbrecht Molecular immunology 67 (2), 193-205, 2015 | 13 | 2015 |
| Broadening a SARS-CoV-1–neutralizing antibody for potent SARS-CoV-2 neutralization through directed evolution F Zhao, M Yuan, C Keating, N Shaabani, O Limbo, C Joyce, J Woehl, ... Science Signaling 16 (798), eabk3516, 2023 | 9 | 2023 |
| An Irreversible Inhibitor to Probe the Role of Streptococcus pyogenes Cysteine Protease SpeB in Evasion of Host Complement Defenses JL Woehl, S Kitamura, N Dillon, Z Han, LJ Edgar, V Nizet, DW Wolan ACS chemical biology 15 (8), 2060-2069, 2020 | 8 | 2020 |
| Fully synthetic platform to rapidly generate tetravalent bispecific nanobody–based immunoglobulins L Misson Mindrebo, H Liu, G Ozorowski, Q Tran, J Woehl, I Khalek, ... Proceedings of the National Academy of Sciences 120 (24), e2216612120, 2023 | 7 | 2023 |
| Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways F Zhao, C Keating, G Ozorowski, N Shaabani, IM Francino-Urdaniz, ... Iscience 25 (9), 2022 | 6 | 2022 |
| Rapid isolation of potent SARS-CoV-2 neutralizing antibodies and protection in a small animal model TF Rodgers, F Zhao, D Huang, N Beutler, RK Abbott, S Callaghan, ... bioRxiv, 2020 | 5* | 2020 |
| Synthetic development of a broadly neutralizing antibody against snake venom long-chain α-neurotoxins IS Khalek, RR Senji Laxme, YTK Nguyen, S Khochare, RN Patel, J Woehl, ... Science Translational Medicine 16 (735), eadk1867, 2024 | 4 | 2024 |
| Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies C Joyce, S Murrell, B Murrell, O Omorodion, LS Ver, N Carrico, R Bastidas, ... PLoS pathogens 19 (6), e1011416, 2023 | 2 | 2023 |
| Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire P Altman, G Ozorowski, R Stanfield, J Haakenson, M Appel, M Parren, ... bioRxiv, 2024.02. 13.580058, 2024 | 1 | 2024 |
| Suggested searches J Zhang, F Yin, L Qiao, G Liu, C Dufresnes, D Jablonski, PC Cooney, ... Perspective, 2024 | | 2024 |
Dennis WolanSenior Principal Scientist, GenentechVerified email at gene.com
