Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis CJ Sinal, M Tohkin, M Miyata, JM Ward, G Lambert, FJ Gonzalez Cell 102 (6), 731-744, 2000 | 2005 | 2000 |
Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism KB Goralski, TC McCarthy, EA Hanniman, BA Zabel, EC Butcher, ... Journal of Biological Chemistry 282 (38), 28175-28188, 2007 | 1172 | 2007 |
Chemerin: at the crossroads of inflammation and obesity MC Ernst, CJ Sinal Trends in Endocrinology & Metabolism 21 (11), 660-667, 2010 | 661 | 2010 |
Adipocyte differentiation of bone marrow-derived mesenchymal stem cells: cross talk with the osteoblastogenic program S Muruganandan, AA Roman, CJ Sinal Cellular and molecular life sciences 66, 236-253, 2009 | 588 | 2009 |
The farnesoid X-receptor is an essential regulator of cholesterol homeostasis G Lambert, MJA Amar, G Guo, HB Brewer, FJ Gonzalez, CJ Sinal Journal of Biological Chemistry 278 (4), 2563-2570, 2003 | 483 | 2003 |
Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450 EG Schuetz, S Strom, K Yasuda, V Lecureur, M Assem, C Brimer, ... Journal of Biological Chemistry 276 (42), 39411-39418, 2001 | 453 | 2001 |
Peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α) regulates triglyceride metabolism by activation of the nuclear receptor FXR Y Zhang, LW Castellani, CJ Sinal, FJ Gonzalez, PA Edwards Genes & development 18 (2), 157-169, 2004 | 447 | 2004 |
Regulation of drug-metabolizing enzymes and transporters in infection, inflammation, and cancer ET Morgan, KB Goralski, M Piquette-Miller, KW Renton, GR Robertson, ... Drug Metabolism and Disposition 36 (2), 205-216, 2008 | 440 | 2008 |
Targeted disruption of soluble epoxide hydrolase reveals a role in blood pressure regulation CJ Sinal, M Miyata, M Tohkin, K Nagata, JR Bend, FJ Gonzalez Journal of Biological Chemistry 275 (51), 40504-40510, 2000 | 427 | 2000 |
Farnesoid X-activated receptor induces apolipoprotein C-II transcription: a molecular mechanism linking plasma triglyceride levels to bile acids HR Kast, CM Nguyen, CJ Sinal, SA Jones, BA Laffitte, K Reue, ... Molecular endocrinology 15 (10), 1720-1728, 2001 | 414 | 2001 |
Complementary roles of farnesoid X receptor, pregnane X receptor, and constitutive androstane receptor in protection against bile acid toxicity GL Guo, G Lambert, M Negishi, JM Ward, HB Brewer, SA Kliewer, ... Journal of Biological Chemistry 278 (46), 45062-45071, 2003 | 363 | 2003 |
Chemerin exacerbates glucose intolerance in mouse models of obesity and diabetes MC Ernst, M Issa, KB Goralski, CJ Sinal Endocrinology 151 (5), 1998-2007, 2010 | 361 | 2010 |
Aryl hydrocarbon receptor-dependent induction of cyp1a1 by bilirubin in mouse hepatoma hepa 1c1c7 cells CJ Sinal, JR Bend Molecular pharmacology 52 (4), 590-599, 1997 | 345 | 1997 |
Towards an integrative approach to understanding the role of chemerin in human health and disease JL Rourke, HJ Dranse, CJ Sinal Obesity Reviews 14 (3), 245-262, 2013 | 325 | 2013 |
Liver receptor homologue-1 mediates species-and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter F Chen, L Ma, PA Dawson, CJ Sinal, E Sehayek, FJ Gonzalez, J Breslow, ... Journal of Biological Chemistry 278 (22), 19909-19916, 2003 | 307 | 2003 |
Serum chemerin levels vary with time of day and are modified by obesity and tumor necrosis factor-α SD Parlee, MC Ernst, S Muruganandan, CJ Sinal, KB Goralski Endocrinology 151 (6), 2590-2602, 2010 | 266 | 2010 |
Role of soluble epoxide hydrolase in postischemic recovery of heart contractile function JM Seubert, CJ Sinal, J Graves, LM DeGraff, JA Bradbury, CR Lee, ... Circulation research 99 (4), 442-450, 2006 | 238 | 2006 |
Role of chemerin/CMKLR1 signaling in adipogenesis and osteoblastogenesis of bone marrow stem cells S Muruganandan, AA Roman, CJ Sinal Journal of Bone and Mineral Research 25 (2), 222-234, 2010 | 230 | 2010 |
Disruption of the chemokine-like receptor-1 (CMKLR1) gene is associated with reduced adiposity and glucose intolerance MC Ernst, ID Haidl, LA Zúñiga, HJ Dranse, JL Rourke, BA Zabel, ... Endocrinology 153 (2), 672-682, 2012 | 208 | 2012 |
Loss of functional farnesoid X receptor increases atherosclerotic lesions in apolipoprotein E-deficient mice EA Hanniman, G Lambert, TC McCarthy, CJ Sinal Journal of lipid research 46 (12), 2595-2604, 2005 | 205 | 2005 |