| Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD J Wu, MR Basha, B Brock, DP Cox, F Cardozo-Pelaez, CA McPherson, ... Journal of Neuroscience 28 (1), 3-9, 2008 | 524 | 2008 |
| The LEARn model: an epigenetic explanation for idiopathic neurobiological diseases DK Lahiri, B Maloney, NH Zawia Molecular Psychiatry 14 (11), 992-1003, 2009 | 256 | 2009 |
| Transcriptional regulation of β-secretase by p25/cdk5 leads to enhanced amyloidogenic processing Y Wen, WH Yu, B Maloney, J Bailey, J Ma, I Marié, T Maurin, L Wang, ... Neuron 57 (5), 680-690, 2008 | 225 | 2008 |
| Virus-like particle expression and assembly in plants: hepatitis B and Norwalk viruses Z Huang, G Elkin, BJ Maloney, N Beuhner, CJ Arntzen, Y Thanavala, ... Vaccine 23 (15), 1851-1858, 2005 | 223 | 2005 |
| Copper depletion down-regulates expression of the Alzheimer's disease amyloid-β precursor protein gene SA Bellingham, DK Lahiri, B Maloney, S La Fontaine, G Multhaup, ... Journal of Biological Chemistry 279 (19), 20378-20386, 2004 | 221 | 2004 |
| Exposure to lead and the developmental origin of oxidative DNA damage in the aging brain CM Bolin, R Basha, D Cox, NH Zawia, B Maloney, DK Lahiri, ... The FASEB Journal 20 (6), 788-790, 2006 | 218 | 2006 |
| Gene structure and organization of the human β-secretase (BACE) promoter K Sambamurti, R Kinsey, B Maloney, YW Ge, DK Lahiri The FASEB Journal 18 (9), 1034-1036, 2004 | 214 | 2004 |
| The experimental Alzheimer's disease drug posiphen [(+)-phenserine] lowers amyloid-β peptide levels in cell culture and mice DK Lahiri, DM Chen, B Maloney, HW Holloway, Q Yu, T Utsuki, ... Journal of Pharmacology and Experimental Therapeutics 320 (1), 386-396, 2007 | 171 | 2007 |
| Autism, Alzheimer disease, and fragile X: APP, FMRP, and mGluR5 are molecular links DK Sokol, B Maloney, JM Long, B Ray, DK Lahiri Neurology 76 (15), 1344-1352, 2011 | 167 | 2011 |
| How and When Environmental Agents and Dietary Factors Affect the Course of Alzheimers Disease: The LEARn Model (Latent Early-Life Associated Regulation) May Explain the … DK Lahiri, B Maloney, M Riyaz Basha, Y Wen Ge, NH Zawia Current Alzheimer Research 4 (2), 219-228, 2007 | 155 | 2007 |
| The Alzheimer's amyloid β-peptide (Aβ) binds a specific DNA Aβ-interacting domain (AβID) in the APP, BACE1, and APOE promoters in a sequence-specific manner: characterizing a … B Maloney, DK Lahiri Gene 488 (1-2), 1-12, 2011 | 147 | 2011 |
| Epigenetics of dementia: understanding the disease as a transformation rather than a state B Maloney, DK Lahiri The Lancet Neurology 15 (7), 760-774, 2016 | 141 | 2016 |
| High levels of Alzheimer beta-amyloid precursor protein (APP) in children with severely autistic behavior and aggression DK Sokol, D Chen, MR Farlow, DW Dunn, B Maloney, JA Zimmer, ... Journal of Child Neurology 21 (6), 444-449, 2006 | 141 | 2006 |
| The “LEARn”(Latent Early–life Associated Regulation) model integrates environmental risk factors and the developmental basis of Alzheimer’s disease, and proposes remedial steps DK Lahiri, B Maloney Experimental Gerontology 45 (4), 291, 2010 | 140 | 2010 |
| Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5′-untranslated region: Implications in Alzheimer’s disease JM Long, B Maloney, JT Rogers, DK Lahiri Molecular psychiatry 24 (3), 345-363, 2019 | 128 | 2019 |
| Functional activity of the novel Alzheimer's amyloid β-peptide interacting domain (AβID) in the APP and BACE1 promoter sequences and implications in activating apoptotic genes … JA Bailey, B Maloney, YW Ge, DK Lahiri Gene 488 (1-2), 13-22, 2011 | 118 | 2011 |
| Lessons from a BACE1 inhibitor trial: Off-site but not off base DK Lahiri, B Maloney, JM Long, NH Greig Alzheimer's & Dementia 10 (5), S411-S419, 2014 | 101 | 2014 |
| Early-emerging cognitive vulnerability to depression and the serotonin transporter promoter region polymorphism EP Hayden, LR Dougherty, B Maloney, TM Olino, H Sheikh, CE Durbin, ... Journal of Affective Disorders 107 (1-3), 227, 2008 | 89 | 2008 |
| Functional characterization of the 5′ flanking region of the BACE gene: identification of a 91 bp fragment involved in basal level of BACE promoter expression YW Ge, B Maloney, K Sambamurti, DK Lahiri The FASEB Journal 18 (9), 1037-1039, 2004 | 75 | 2004 |
| MicroRNA-298 reduces levels of human amyloid-β precursor protein (APP), β-site APP-converting enzyme 1 (BACE1) and specific tau protein moieties N Chopra, R Wang, B Maloney, K Nho, JS Beck, N Pourshafie, ... Molecular psychiatry 26 (10), 5636-5657, 2021 | 74 | 2021 |
Debomoy K LahiriDistinguished Professor, Indiana University School Medicine, Indianapolis, USAVerified email at iupui.edu
