Vectors for co-expression of an unrestricted number of proteins C Scheich, D Kümmel, D Soumailakakis, U Heinemann, K Büssow Nucleic acids research 35 (6), e43, 2007 | 246 | 2007 |
Complexin cross-links prefusion SNAREs into a zigzag array D Kümmel, SS Krishnakumar, DT Radoff, F Li, CG Giraudo, F Pincet, ... Nature structural & molecular biology 18 (8), 927-933, 2011 | 184 | 2011 |
Altered RNA splicing by mutant p53 activates oncogenic RAS signaling in pancreatic cancer LF Escobar-Hoyos, A Penson, R Kannan, H Cho, CH Pan, RK Singh, ... Cancer cell 38 (2), 198-211. e8, 2020 | 130 | 2020 |
A conformational switch in complexin is required for synaptotagmin to trigger synaptic fusion SS Krishnakumar, DT Radoff, D Kümmel, CG Giraudo, F Li, L Khandan, ... Nature structural & molecular biology 18 (8), 934-940, 2011 | 112 | 2011 |
Insights regarding guanine nucleotide exchange from the structure of a DENN-domain protein complexed with its Rab GTPase substrate X Wu, MJ Bradley, Y Cai, D Kümmel, EM De La Cruz, FA Barr, ... Proceedings of the National Academy of Sciences 108 (46), 18672-18677, 2011 | 111 | 2011 |
Principles of membrane tethering and fusion in endosome and lysosome biogenesis D Kümmel, C Ungermann Current opinion in cell biology 29, 61-66, 2014 | 97 | 2014 |
Molecular mechanism to target the endosomal Mon1-Ccz1 GEF complex to the pre-autophagosomal structure J Gao, L Langemeyer, D Kümmel, F Reggiori, C Ungermann Elife 7, e31145, 2018 | 78 | 2018 |
A half-zippered SNARE complex represents a functional intermediate in membrane fusion F Li, D Kümmel, J Coleman, KM Reinisch, JE Rothman, F Pincet Journal of the American Chemical Society 136 (9), 3456-3464, 2014 | 78 | 2014 |
The structure of the TRAPP subunit TPC6 suggests a model for a TRAPP subcomplex D Kümmel, JJ Müller, Y Roske, R Misselwitz, K Büssow, U Heinemann EMBO reports 6 (8), 787-793, 2005 | 70 | 2005 |
Structure of palmitoylated BET3: insights into TRAPP complex assembly and membrane localization AP Turnbull, D Kümmel, B Prinz, C Holz, J Schultchen, C Lang, ... The EMBO Journal 24 (5), 875-884, 2005 | 69 | 2005 |
Structure of membrane tethers and their role in fusion C Ungermann, D Kümmel Traffic 20 (7), 479-490, 2019 | 64 | 2019 |
Architecture and mechanism of the late endosomal Rab7-like Ypt7 guanine nucleotide exchange factor complex Mon1–Ccz1 S Kiontke, L Langemeyer, A Kuhlee, S Schuback, S Raunser, ... Nature communications 8 (1), 14034, 2017 | 64 | 2017 |
Unique self-palmitoylation activity of the transport protein particle component Bet3: a mechanism required for protein stability D Kümmel, U Heinemann, M Veit Proceedings of the National Academy of Sciences 103 (34), 12701-12706, 2006 | 63 | 2006 |
A conserved and regulated mechanism drives endosomal Rab transition L Langemeyer, AC Borchers, E Herrmann, N Füllbrunn, Y Han, A Perz, ... Elife 9, e56090, 2020 | 59 | 2020 |
The synaptobrevin homologue Snc2p recruits the exocyst to secretory vesicles by binding to Sec6p D Shen, H Yuan, A Hutagalung, A Verma, D Kümmel, X Wu, K Reinisch, ... Journal of Cell Biology 202 (3), 509-526, 2013 | 59 | 2013 |
Crystal Structure of F-93 from Sulfolobus Spindle-Shaped Virus 1, a Winged-Helix DNA Binding Protein P Kraft, A Oeckinghaus, D Kümmel, GH Gauss, J Gilmore, B Wiedenheft, ... Journal of virology 78 (21), 11544-11550, 2004 | 55 | 2004 |
Genetic analysis of the Complexin trans-clamping model for cross-linking SNARE complexes in vivo RW Cho, D Kümmel, F Li, SW Baguley, J Coleman, JE Rothman, ... Proceedings of the National Academy of Sciences 111 (28), 10317-10322, 2014 | 52 | 2014 |
Engineered SAM synthetases for enzymatic generation of AdoMet analogs with photocaging groups and reversible DNA modification in cascade reactions F Michailidou, N Klöcker, NV Cornelissen, RK Singh, A Peters, ... Angewandte Chemie International Edition 60 (1), 480-485, 2021 | 49* | 2021 |
Structure of D-63 from Sulfolobus spindle-shaped virus 1: surface properties of the dimeric four-helix bundle suggest an adaptor protein function P Kraft, D Kümmel, A Oeckinghaus, GH Gauss, B Wiedenheft, M Young, ... Journal of virology 78 (14), 7438-7442, 2004 | 48 | 2004 |
Conformational dynamics of calcium-triggered activation of fusion by synaptotagmin SS Krishnakumar, D Kümmel, SJ Jones, DT Radoff, KM Reinisch, ... Biophysical journal 105 (11), 2507-2516, 2013 | 44 | 2013 |