Topological domains in mammalian genomes identified by analysis of chromatin interactions JR Dixon, S Selvaraj, F Yue, A Kim, Y Li, Y Shen, M Hu, JS Liu, B Ren Nature 485 (7398), 376-380, 2012 | 6837 | 2012 |
A high-resolution map of the three-dimensional chromatin interactome in human cells F Jin, Y Li, JR Dixon, S Selvaraj, Z Ye, AY Lee, CA Yen, AD Schmitt, ... Nature 503 (7475), 290-294, 2013 | 1382 | 2013 |
Epigenomic analysis of multilineage differentiation of human embryonic stem cells W Xie, MD Schultz, R Lister, Z Hou, N Rajagopal, P Ray, JW Whitaker, ... Cell 153 (5), 1134-1148, 2013 | 772 | 2013 |
Exploring the trans‐cleavage activity of CRISPR‐Cas12a (cpf1) for the development of a universal electrochemical biosensor Y Dai, RA Somoza, L Wang, JF Welter, Y Li, AI Caplan, CC Liu Angewandte Chemie 131 (48), 17560-17566, 2019 | 477 | 2019 |
Role of the histone H3 lysine 4 methyltransferase, SET7/9, in the regulation of NF-κB-dependent inflammatory genes: relevance to diabetes and inflammation Y Li, MA Reddy, F Miao, N Shanmugam, JK Yee, D Hawkins, B Ren, ... Journal of Biological Chemistry 283 (39), 26771-26781, 2008 | 379 | 2008 |
Epigenetic priming of enhancers predicts developmental competence of hESC-derived endodermal lineage intermediates A Wang, F Yue, Y Li, R Xie, T Harper, NA Patel, K Muth, J Palmer, Y Qiu, ... Cell stem cell 16 (4), 386-399, 2015 | 264 | 2015 |
RFECS: a random-forest based algorithm for enhancer identification from chromatin state N Rajagopal, W Xie, Y Li, U Wagner, W Wang, J Stamatoyannopoulos, ... PLoS computational biology 9 (3), e1002968, 2013 | 244 | 2013 |
CRISPR reveals a distal super-enhancer required for Sox2 expression in mouse embryonic stem cells Y Li, CM Rivera, H Ishii, F Jin, S Selvaraj, AY Lee, JR Dixon, B Ren PloS one 9 (12), e114485, 2014 | 197 | 2014 |
Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling SC Mack, KW Pajtler, L Chavez, K Okonechnikov, KC Bertrand, X Wang, ... Nature 553 (7686), 101-105, 2018 | 195 | 2018 |
Robust Hi-C maps of enhancer-promoter interactions reveal the function of non-coding genome in neural development and diseases L Lu, X Liu, WK Huang, P Giusti-Rodríguez, J Cui, S Zhang, W Xu, Z Wen, ... Molecular cell 79 (3), 521-534. e15, 2020 | 140 | 2020 |
Proinflammatory effects of advanced lipoxidation end products in monocytes N Shanmugam, JL Figarola, Y Li, PM Swiderski, S Rahbar, R Natarajan Diabetes 57 (4), 879-888, 2008 | 107 | 2008 |
Single-cell heterogeneity analysis and CRISPR screen identify key β-cell-specific disease genes Z Fang, C Weng, H Li, R Tao, W Mai, X Liu, L Lu, S Lai, Q Duan, C Alvarez, ... Cell reports 26 (11), 3132-3144. e7, 2019 | 101 | 2019 |
PU. 1 and C/EBPα synergistically program distinct response to NF-κB activation through establishing monocyte specific enhancers F Jin, Y Li, B Ren, R Natarajan Proceedings of the National Academy of Sciences 108 (13), 5290-5295, 2011 | 93 | 2011 |
Using three-dimensional regulatory chromatin interactions from adult and fetal cortex to interpret genetic results for psychiatric disorders and cognitive traits P Giusti-Rodríguez, L Lu, Y Yang, CA Crowley, X Liu, I Juric, JS Martin, ... BioRxiv, 406330, 2018 | 70* | 2018 |
Enhancers: multi-dimensional signal integrators F Jin, Y Li, B Ren, R Natarajan Transcription 2 (5), 226-230, 2011 | 48 | 2011 |
Single-cell lineage analysis reveals extensive multimodal transcriptional control during directed beta-cell differentiation C Weng, J Xi, H Li, J Cui, A Gu, S Lai, K Leskov, L Ke, F Jin, Y Li Nature metabolism 2 (12), 1443-1458, 2020 | 44 | 2020 |
Chemical screening identifies enhancers of mutant oligodendrocyte survival and unmasks a distinct pathological phase in Pelizaeus-Merzbacher disease MS Elitt, HE Shick, M Madhavan, KC Allan, BLL Clayton, C Weng, ... Stem Cell Reports 11 (3), 711-726, 2018 | 34 | 2018 |
DeepLoop robustly maps chromatin interactions from sparse allele-resolved or single-cell Hi-C data at kilobase resolution S Zhang, D Plummer, L Lu, J Cui, W Xu, M Wang, X Liu, N Prabhakar, ... Nature genetics 54 (7), 1013-1025, 2022 | 27 | 2022 |
Myt transcription factors prevent stress-response gene overactivation to enable postnatal pancreatic β cell proliferation, function, and survival R Hu, E Walker, C Huang, Y Xu, C Weng, GE Erickson, A Coldren, X Yang, ... Developmental cell 53 (4), 390-405. e10, 2020 | 13 | 2020 |
TWO‐SIGMA: A novel two‐component single cell model‐based association method for single‐cell RNA‐seq data E Van Buren, M Hu, C Weng, F Jin, Y Li, D Wu, Y Li Genetic epidemiology 45 (2), 142-153, 2021 | 10 | 2021 |