Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism Q Huang, C Stalnecker, C Zhang, LA McDermott, P Iyer, J O’Neill, ... Journal of Biological Chemistry 293 (10), 3535-3545, 2018 | 92 | 2018 |
Design and evaluation of novel glutaminase inhibitors LA McDermott, P Iyer, L Vernetti, S Rimer, J Sun, M Boby, T Yang, ... Bioorganic & medicinal chemistry 24 (8), 1819-1839, 2016 | 67 | 2016 |
Design and activity of AP endonuclease-1 inhibitors Z Feng, S Kochanek, D Close, LR Wang, A Srinivasan, AA Almehizia, ... Journal of chemical biology 8, 79-93, 2015 | 32 | 2015 |
Mutagenicity of N3-methyladenine: a multi-translesion polymerase affair P Monti, I Traverso, L Casolari, P Menichini, A Inga, L Ottaggio, D Russo, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 683 (1 …, 2010 | 23 | 2010 |
Synthesis and structure–activity analysis of diphenylpyrazolodiazene inhibitors of the HIV-1 Nef virulence factor PC Iyer, J Zhao, LA Emert-Sedlak, KK Moore, TE Smithgall, BW Day Bioorganic & medicinal chemistry letters 24 (7), 1702-1706, 2014 | 20 | 2014 |
Connecting neuronal cell protective pathways and drug combinations in a Huntington’s disease model through the application of quantitative systems pharmacology F Pei, H Li, MJ Henderson, SA Titus, A Jadhav, A Simeonov, ... Scientific Reports 7 (1), 17803, 2017 | 19 | 2017 |
An expeditious synthesis of a β-silylethanol anchoring group by a silicon directed Baeyer–Villiger oxidation on solid-phase P Iyer, SK Ghosh Tetrahedron letters 43 (51), 9437-9440, 2002 | 18 | 2002 |
Synthesis and characterization of DNA minor groove binding alkylating agents P Iyer, A Srinivasan, SK Singh, GP Mascara, S Zayitova, B Sidone, ... Chemical research in toxicology 26 (1), 156-168, 2013 | 16 | 2013 |
A Rapid and Efficient Synthesis of a Bifunctional β‐Silylketone, Precursor for a Solid Supported β‐Silylethanol Anchoring Group SM Date, P Iyer, SK Ghosh Synthetic communications 34 (3), 405-411, 2004 | 12 | 2004 |
GAC inhibitors with a 4-hydroxypiperidine spacer: Requirements for potency L McDermott, D Koes, S Mohammed, P Iyer, M Boby, V Balasubramanian, ... Bioorganic & medicinal chemistry letters 29 (19), 126632, 2019 | 11 | 2019 |
Current landscape of coccidioidomycosis R Boro, PC Iyer, MA Walczak Journal of Fungi 8 (4), 413, 2022 | 10 | 2022 |
High frequency of genomic deletions induced by Me-lex, a sequence selective N3-adenine methylating agent, at the Hprt locus in Chinese hamster ovary cells D Russo, G Fronza, L Ottaggio, P Monti, A Inga, P Iyer, B Gold, ... Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 671 (1 …, 2009 | 7 | 2009 |
3‘-H-Phosphonate Synthesis of Chiral Benzo[a]pyrene Diol Epoxide Adducts at N2 of Deoxyguanosine in Oligonucleotides PC Iyer, H Yagi, JM Sayer, DM Jerina Chemical research in toxicology 20 (2), 311-315, 2007 | 5 | 2007 |
XRCC1 deficiency influences the cytotoxicity and the genomic instability induced by Me-lex, a specific inducer of N3-methyladenine D Russo, G Fronza, L Ottaggio, P Monti, C Perfumo, A Inga, P Iyer, B Gold, ... DNA repair 9 (7), 728-736, 2010 | 2 | 2010 |
Compounds for treating hiv and methods for using the compounds TE Smithgall, LA Emert-Sedlak, BW Day, J Zhao, PC Iyer US Patent 9,695,127, 2017 | 1 | 2017 |
Hdac inhibitors P Wipf, DM Huryn, MG Laporte, L Terrab, MJ Houghton, A Topacio, ... US Patent App. 18/039,941, 2024 | | 2024 |
Glutaminase inhibitors LA McDermott, PC Iyer, RA Cerione, WP Katt US Patent 11,013,724, 2021 | | 2021 |
Glutaminase inhibitors LA McDermott, PC Iyer, RA Cerione, WP Katt US Patent 10,245,254, 2019 | | 2019 |
Synthesis and Biological Characterization of Minor Groove Binding Methylating Agents P Iyer, S Singh, A Srinivasan, B Gold, G Mascara CHEMICAL RESEARCH IN TOXICOLOGY 23 (1), 284-284, 2010 | | 2010 |
TOXI 86-Synthesis and biological characterization of minor groove binding methylating agents P Iyer, S Singh, A Srinivasan, B Gold, G Mascara ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 238, 2009 | | 2009 |