A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin VK Chaudhary, G Queen, RP Junghans, TA Waldmann, DJ FitzGerald, ... Nature 339 (6223), 394-397, 1989 | 612 | 1989 |
Recombinant toxins as novel therapeutic agents I Pastan, V Chaudhary, DJ FitzGerald Annual review of biochemistry 61 (1), 331-354, 1992 | 470 | 1992 |
A rapid method of cloning functional variable-region antibody genes in Escherichia coli as single-chain immunotoxins. VK Chaudhary, JK Batra, MG Gallo, MC Willingham, DJ FitzGerald, ... Proceedings of the National Academy of Sciences 87 (3), 1066-1070, 1990 | 367 | 1990 |
Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity. VK Chaudhary, Y Jinno, D FitzGerald, I Pastan Proceedings of the National Academy of Sciences 87 (1), 308-312, 1990 | 366 | 1990 |
Selective killing of HIV-infected cells by recombinant human CD4-Pseudomonas exotoxin hybrid protein VK Chaudhary, T Mizukami, TR Fuerst, DJ FitzGerald, B Moss, I Pastan, ... Nature 335 (6188), 369-372, 1988 | 336 | 1988 |
Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol M Ogata, VK Chaudhary, I Pastan, DJ FitzGerald Journal of Biological Chemistry 265 (33), 20678-20685, 1990 | 333 | 1990 |
Increased cytotoxic activity of Pseudomonas exotoxin and two chimeric toxins ending in KDEL. S Seetharam, VK Chaudhary, D FitzGerald, I Pastan Journal of Biological Chemistry 266 (26), 17376-17381, 1991 | 279 | 1991 |
Functional analysis of domains II, Ib, and III of Pseudomonas exotoxin CB Siegall, VK Chaudhary, DJ FitzGerald, I Pastan Journal of Biological Chemistry 264 (24), 14256-14261, 1989 | 266 | 1989 |
Activity of a recombinant fusion protein between transforming growth factor type alpha and Pseudomonas toxin. VK Chaudhary, DJ FitzGerald, S Adhya, I Pastan Proceedings of the National Academy of Sciences 84 (13), 4538-4542, 1987 | 232 | 1987 |
Cytotoxic activity of an interleukin 2-Pseudomonas exotoxin chimeric protein produced in Escherichia coli. H Lorberboum-Galski, D FitzGerald, V Chaudhary, S Adhya, I Pastan Proceedings of the National Academy of Sciences 85 (6), 1922-1926, 1988 | 224 | 1988 |
A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo Y Singh, VK Chaudhary, SH Leppla Journal of Biological Chemistry 264 (32), 19103-19107, 1989 | 206 | 1989 |
Activity of immunotoxins constructed with modified Pseudomonas exotoxin A lacking the cell recognition domain. T Kondo, D FitzGerald, VK Chaudhary, S Adhya, I Pastan Journal of Biological Chemistry 263 (19), 9470-9475, 1988 | 205 | 1988 |
Recombinant immunotoxins containing anti-Tac (Fv) and derivatives of Pseudomonas exotoxin produce complete regression in mice of an interleukin-2 receptor-expressing human … RJ Kreitman, P Bailon, VK Chaudhary, DJ FitzGerald, I Pastan | 174 | 1994 |
A recombinant single-chain immunotoxin composed of anti-Tac variable regions and a truncated diphtheria toxin. VK Chaudhary, MG Gallo, DJ FitzGerald, I Pastan Proceedings of the National Academy of Sciences 87 (23), 9491-9494, 1990 | 159 | 1990 |
Anti-Tac (Fv)-PE40, a single chain antibody Pseudomonas fusion protein directed at interleukin 2 receptor bearing cells. JK Batra, D FitzGerald, M Gately, VK Chaudhary, I Pastan Journal of Biological Chemistry 265 (25), 15198-15202, 1990 | 155 | 1990 |
Phytochemicals as antiviral agents: recent updates R Ghildiyal, V Prakash, VK Chaudhary, V Gupta, R Gabrani Plant-derived bioactives: production, properties and therapeutic …, 2020 | 151 | 2020 |
Single-Chain Immunotoxins Directed at the Human Transferrin Receptor Containing Pseudomonas Exotoxin A or Diphtheria Toxin: Anti-TFR(Fv)-PE40 and DT388 … JK Batra, DJ Fitzgerald, VK Chaudhary, I Pastan Molecular and cellular biology 11 (4), 2200-2205, 1991 | 144 | 1991 |
The carboxyl-terminal end of protective antigen is required for receptor binding and anthrax toxin activity Y Singh, KR Klimpel, CP Quinn, VK Chaudhary, SH Leppla Journal of Biological Chemistry 266 (23), 15493-15497, 1991 | 125 | 1991 |
Domain II mutants of Pseudomonas exotoxin deficient in translocation Y Jinno, M Ogata, VK Chaudhary, MC Willingham, S Adhya, D FitzGerald, ... Journal of Biological Chemistry 264 (27), 15953-15959, 1989 | 125 | 1989 |
Cytotoxic activity of an interleukin 6-Pseudomonas exotoxin fusion protein on human myeloma cells. CB Siegall, VK Chaudhary, DJ FitzGerald, I Pastan Proceedings of the National Academy of Sciences 85 (24), 9738-9742, 1988 | 121 | 1988 |