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Vijay K Chaudhary
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A recombinant immunotoxin consisting of two antibody variable domains fused to Pseudomonas exotoxin
VK Chaudhary, G Queen, RP Junghans, TA Waldmann, DJ FitzGerald, ...
Nature 339 (6223), 394-397, 1989
5821989
Recombinant toxins as novel therapeutic agents
I Pastan, V Chaudhary, DJ FitzGerald
Annual review of biochemistry 61 (1), 331-354, 1992
4571992
A rapid method of cloning functional variable-region antibody genes in Escherichia coli as single-chain immunotoxins.
VK Chaudhary, JK Batra, MG Gallo, MC Willingham, DJ FitzGerald, ...
Proceedings of the National Academy of Sciences 87 (3), 1066-1070, 1990
3481990
Pseudomonas exotoxin contains a specific sequence at the carboxyl terminus that is required for cytotoxicity.
VK Chaudhary, Y Jinno, D FitzGerald, I Pastan
Proceedings of the National Academy of Sciences 87 (1), 308-312, 1990
3461990
Selective killing of HIV-infected cells by recombinant human CD4-Pseudomonas exotoxin hybrid protein
VK Chaudhary, T Mizukami, TR Fuerst, DJ FitzGerald, B Moss, I Pastan, ...
Nature 335 (6188), 369-372, 1988
3261988
Processing of Pseudomonas exotoxin by a cellular protease results in the generation of a 37,000-Da toxin fragment that is translocated to the cytosol
M Ogata, VK Chaudhary, I Pastan, DJ FitzGerald
Journal of Biological Chemistry 265 (33), 20678-20685, 1990
3201990
Increased cytotoxic activity of Pseudomonas exotoxin and two chimeric toxins ending in KDEL.
S Seetharam, VK Chaudhary, D FitzGerald, I Pastan
Journal of Biological Chemistry 266 (26), 17376-17381, 1991
2751991
Functional analysis of domains II, Ib, and III of Pseudomonas exotoxin
CB Siegall, VK Chaudhary, DJ FitzGerald, I Pastan
Journal of Biological Chemistry 264 (24), 14256-14261, 1989
2521989
Activity of a recombinant fusion protein between transforming growth factor type alpha and Pseudomonas toxin.
VK Chaudhary, DJ FitzGerald, S Adhya, I Pastan
Proceedings of the National Academy of Sciences 84 (13), 4538-4542, 1987
2111987
Cytotoxic activity of an interleukin 2-Pseudomonas exotoxin chimeric protein produced in Escherichia coli.
H Lorberboum-Galski, D FitzGerald, V Chaudhary, S Adhya, I Pastan
Proceedings of the National Academy of Sciences 85 (6), 1922-1926, 1988
2081988
A deleted variant of Bacillus anthracis protective antigen is non-toxic and blocks anthrax toxin action in vivo
Y Singh, VK Chaudhary, SH Leppla
Journal of Biological Chemistry 264 (32), 19103-19107, 1989
2041989
Activity of immunotoxins constructed with modified Pseudomonas exotoxin A lacking the cell recognition domain.
T Kondo, D FitzGerald, VK Chaudhary, S Adhya, I Pastan
Journal of Biological Chemistry 263 (19), 9470-9475, 1988
2001988
Recombinant immunotoxins containing anti-Tac (Fv) and derivatives of Pseudomonas exotoxin produce complete regression in mice of an interleukin-2 receptor-expressing human …
RJ Kreitman, P Bailon, VK Chaudhary, DJ FitzGerald, I Pastan
1701994
Anti-Tac (Fv)-PE40, a single chain antibody Pseudomonas fusion protein directed at interleukin 2 receptor bearing cells.
JK Batra, D FitzGerald, M Gately, VK Chaudhary, I Pastan
Journal of Biological Chemistry 265 (25), 15198-15202, 1990
1481990
A recombinant single-chain immunotoxin composed of anti-Tac variable regions and a truncated diphtheria toxin.
VK Chaudhary, MG Gallo, DJ FitzGerald, I Pastan
Proceedings of the National Academy of Sciences 87 (23), 9491-9494, 1990
1451990
Single-chain immunotoxins directed at the human transferrin receptor containing Pseudomonas exotoxin A or diphtheria toxin: anti-TFR (Fv)-PE40 and DT388-anti-TFR (Fv)
JK Batra, DJ Fitzgerald, VK Chaudhary, I Pastan
Molecular and cellular biology 11 (4), 2200-2205, 1991
1401991
The carboxyl-terminal end of protective antigen is required for receptor binding and anthrax toxin activity
Y Singh, KR Klimpel, CP Quinn, VK Chaudhary, SH Leppla
Journal of Biological Chemistry 266 (23), 15493-15497, 1991
1221991
Domain II mutants of Pseudomonas exotoxin deficient in translocation
Y Jinno, M Ogata, VK Chaudhary, MC Willingham, S Adhya, D FitzGerald, ...
Journal of Biological Chemistry 264 (27), 15953-15959, 1989
1221989
Mutational analysis of domain I of Pseudomonas exotoxin. Mutations in domain I of Pseudomonas exotoxin which reduce cell binding and animal toxicity.
Y Jinno, VK Chaudhary, T Kondo, S Adhya, DJ FitzGerald, I Pastan
Journal of Biological Chemistry 263 (26), 13203-13207, 1988
1151988
Cytotoxic activity of an interleukin 6-Pseudomonas exotoxin fusion protein on human myeloma cells.
CB Siegall, VK Chaudhary, DJ FitzGerald, I Pastan
Proceedings of the National Academy of Sciences 85 (24), 9738-9742, 1988
1071988
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