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| Exendin‐4 protects pancreatic beta cells from human islet amyloid polypeptide‐induced cell damage: potential involvement of AKT and mitochondria biogenesis R Fan, X Li, X Gu, JCN Chan, G Xu Diabetes, Obesity and Metabolism 12 (9), 815-824, 2010 | 99 | 2010 |
| Involvement of mitochondrial dysfunction in human islet amyloid polypeptide-induced apoptosis in INS-1E pancreatic beta cells: An effect attenuated by phycocyanin XL Li, T Chen, YS Wong, G Xu, RR Fan, HL Zhao, JCN Chan The international journal of biochemistry & cell biology 43 (4), 525-534, 2011 | 92 | 2011 |
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| Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes R Fan, A Toubal, S Goni, K Drareni, Z Huang, F Alzaid, R Ballaire, P Ancel, ... Nature medicine 22 (7), 780-791, 2016 | 85 | 2016 |
| Global trend of diabetes mortality attributed to vascular complications, 2000–2016 W Ling, Y Huang, YM Huang, RR Fan, Y Sui, HL Zhao Cardiovascular Diabetology 19, 1-12, 2020 | 80 | 2020 |
| Pharmacological reduction of NEFA restores the efficacy of incretin-based therapies through GLP-1 receptor signalling in the beta cell in mouse models of diabetes ZF Kang, Y Deng, Y Zhou, RR Fan, JCN Chan, DR Laybutt, J Luzuriaga, ... Diabetologia 56, 423-433, 2013 | 80 | 2013 |
| Fat redistribution and adipocyte transformation in uninephrectomized rats HL Zhao, Y Sui, J Guan, L He, X Zhu, RR Fan, G Xu, APS Kong, CS Ho, ... Kidney international 74 (4), 467-477, 2008 | 72 | 2008 |
| Lifestyle and metabolic factors for nonalcoholic fatty liver disease: Mendelian randomization study S Yuan, J Chen, X Li, R Fan, B Arsenault, D Gill, EL Giovannucci, J Zheng, ... European journal of epidemiology 37 (7), 723-733, 2022 | 68 | 2022 |
| Sirt3 deficiency increased the vulnerability of pancreatic beta cells to oxidative stress-induced dysfunction Y Zhou, ACK Chung, R Fan, HM Lee, G Xu, B Tomlinson, JCN Chan, ... Antioxidants & redox signaling 27 (13), 962-976, 2017 | 59 | 2017 |
| The Combined Expression of Pdx1 and MafA with Either Ngn3 or NeuroD Improves the Differentiation Efficiency of Mouse Embryonic Stem Cells into Insulin … H Xu, KS Tsang, JCN Chan, P Yuan, R Fan, H Kaneto, G Xu Cell transplantation 22 (1), 147-158, 2013 | 50 | 2013 |
| Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα N Liang, A Damdimopoulos, S Goñi, Z Huang, LL Vedin, T Jakobsson, ... Nature communications 10, 2019 | 48 | 2019 |
| c-Jun/AP-1 overexpression reprograms ERα signaling related to tamoxifen response in ERα-positive breast cancer H He, I Sinha, R Fan, LA Haldosen, F Yan, C Zhao, K Dahlman-Wright Oncogene 37 (19), 2586-2600, 2018 | 47 | 2018 |
| GPS2 deficiency triggers maladaptive white adipose tissue expansion in obesity via HIF1A activation K Drareni, R Ballaire, S Barilla, MJ Mathew, A Toubal, R Fan, N Liang, ... Cell reports 24 (11), 2957-2971. e6, 2018 | 46 | 2018 |
| Transcriptional repression in macrophages—basic mechanisms and alterations in metabolic inflammatory diseases E Treuter, R Fan, Z Huang, T Jakobsson, N Venteclef FEBS letters 591 (19), 2959-2977, 2017 | 39 | 2017 |
| Exendin-4 improves blood glucose control in both young and aging normal non-diabetic mice, possible contribution of beta cell independent effects R Fan, Z Kang, L He, J Chan, G Xu PLoS One 6 (5), e20443, 2011 | 38 | 2011 |
| The nuclear receptor—Co-repressor complex in control of liver metabolism and disease N Liang, T Jakobsson, R Fan, E Treuter Frontiers in endocrinology 10, 464244, 2019 | 37 | 2019 |
| Nuclear receptor coregulators in metabolism and disease M Giudici, S Goni, R Fan, E Treuter Metabolic Control, 95-135, 2016 | 34 | 2016 |
| The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages Z Huang, N Liang, S Goni, A Damdimopoulos, C Wang, R Ballaire, ... Molecular cell 81 (5), 953-968. e9, 2021 | 33 | 2021 |
| Oncolytic Parapoxvirus induces Gasdermin E-mediated pyroptosis and activates antitumor immunity JGWH Jing Lin, Shihui Sun, Kui Zhao, Fei Gao, Renling Wang, Qi Li, Yanlong ... Nature Communications 14 (224), 2023 | 29 | 2023 |
