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Navneet Matharu
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CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency
N Matharu, S Rattanasopha, S Tamura, L Maliskova, Y Wang, A Bernard, ...
Science 363 (6424), eaau0629, 2019
2742019
Minor loops in major folds: enhancer–promoter looping, chromatin restructuring, and their association with transcriptional regulation and disease
N Matharu, N Ahituv
PLoS genetics 11 (12), e1005640, 2015
1042015
Vertebrate Homologue of Drosophila GAGA Factor
NK Matharu, T Hussain, R Sankaranarayanan, RK Mishra
Journal of molecular biology 400 (3), 434-447, 2010
772010
Oestrogen engages brain MC4R signalling to drive physical activity in female mice
WC Krause, R Rodriguez, B Gegenhuber, N Matharu, AN Rodriguez, ...
Nature 599 (7883), 131-135, 2021
712021
Modulating gene regulation to treat genetic disorders
N Matharu, N Ahituv
Nature Reviews Drug Discovery 19 (11), 757-775, 2020
552020
Toward a neurospheroid niche model: Optimizing embedded 3D bioprinting for fabrication of neurospheroid brain-like co-culture constructs
YCE Li, YA Jodat, R Samanipour, G Zorzi, K Zhu, M Hirano, K Chang, ...
Biofabrication 13 (1), 015014, 2020
442020
Genetic variation in the SIM1 locus is associated with erectile dysfunction
E Jorgenson, N Matharu, MR Palmer, J Yin, J Shan, TJ Hoffmann, KK Thai, ...
Proceedings of the National Academy of Sciences 115 (43), 11018-11023, 2018
282018
A functionally conserved Polycomb response element from mouse HoxD complex responds to heterochromatin factors
D Vasanthi, A Nagabhushan, NK Matharu, RK Mishra
Scientific reports 3 (1), 3011, 2013
272013
Chromatin insulators and topological domains: adding new dimensions to 3D genome architecture
NK Matharu, SH Ahanger
Genes 6 (3), 790-811, 2015
192015
Genomic and epigenomic mapping of leptin-responsive neuronal populations involved in body weight regulation
F Inoue, WL Eckalbar, Y Wang, KK Murphy, N Matharu, C Vaisse, ...
Nature metabolism 1 (4), 475-484, 2019
182019
CRISPR activation rescues abnormalities in SCN2A haploinsufficiency-associated autism spectrum disorder
S Tamura, AD Nelson, PWE Spratt, H Kyoung, X Zhou, Z Li, J Zhao, ...
BioRxiv, 2022.03. 30.486483, 2022
132022
Gene therapy for haploinsufficiency
N Ahituv, N Matharu
US Patent 11,730,828, 2023
72023
Transcriptomic mapping of neural diversity, differentiation and functional trajectory in ipsc-derived 3d brain organoid models
K Kiaee, YA Jodat, NJ Bassous, N Matharu, SR Shin
Cells 10 (12), 3422, 2021
72021
Asymmetron: a toolkit for the identification of strand asymmetry patterns in biological sequences
I Georgakopoulos-Soares, I Mouratidis, GE Parada, N Matharu, ...
Nucleic acids research 49 (1), e4-e4, 2021
62021
Role of vertebrate GAGA associated factor (vGAF) in early development of zebrafish
NK Matharu, S Yadav, M Kumar, RK Mishra
Cells & Development 166, 203682, 2021
42021
Estrogen Drives Melanocortin Neurons To Increase Spontaneous Activity and Reduce Sedentary Behavior
WC Krause, R Rodriguez, B Gegenhuber, N Matharu, AN Rodriguez, ...
bioRxiv, 794792, 2019
32019
Homeotic gene regulation: a paradigm for epigenetic mechanisms underlying organismal development
NK Matharu, V Dasari, RK Mishra
Epigenetics: Development and Disease, 177-207, 2012
32012
Promoter or enhancer activation by CRISPRa rescues haploinsufficiency caused obesity
N Matharu, S Rattanasopha, L Maliskova, Y Wang, A Hardin, C Vaisse, ...
BioRxiv, 140426, 2017
12017
Tone up your chromatin and stay young
NK Matharu, RK Mishra
Journal of biosciences 36, 5-11, 2011
12011
Genomic and epigenomic mapping of leptin-responsive neuronal populations involved in body weight regulation (vol 1, pg pages475, 2019)
F Inoue, WL Eckalbar, Y Wang, KK Murphy, N Matharu, C Vaisse, ...
NATURE METABOLISM, 2024
2024
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Articles 1–20