Joshy George
Joshy George
Associate Director, Computational Sciences, Jackson Laboratory for Genomic Medicine, Connecticut
Verified email at jax.org
TitleCited byYear
The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells
YH Loh, Q Wu, JL Chew, VB Vega, W Zhang, X Chen, G Bourque, ...
Nature genetics 38 (4), 431, 2006
24972006
An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival
LD Miller, J Smeds, J George, VB Vega, L Vergara, A Ploner, Y Pawitan, ...
Proceedings of the National Academy of Sciences 102 (38), 13550-13555, 2005
12702005
Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome
RW Tothill, AV Tinker, J George, R Brown, SB Fox, S Lade, DS Johnson, ...
Clinical cancer research 14 (16), 5198-5208, 2008
9652008
BRCA mutation frequency and patterns of treatment response in BRCA mutation–positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group
K Alsop, S Fereday, C Meldrum, A DeFazio, C Emmanuel, J George, ...
Journal of Clinical Oncology 30 (21), 2654, 2012
7032012
Genetic reclassification of histologic grade delineates new clinical subtypes of breast cancer
AV Ivshina, J George, O Senko, B Mow, TC Putti, J Smeds, T Lindahl, ...
Cancer research 66 (21), 10292-10301, 2006
6662006
Whole–genome characterization of chemoresistant ovarian cancer
AM Patch, EL Christie, D Etemadmoghadam, DW Garsed, J George, ...
Nature 521 (7553), 489, 2015
6292015
Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells
YH Loh, W Zhang, X Chen, J George, HH Ng
Genes & development 21 (20), 2545-2557, 2007
4842007
Whole-genome cartography of estrogen receptor α binding sites
CY Lin, VB Vega, JS Thomsen, T Zhang, SL Kong, M Xie, KP Chiu, ...
PLoS genetics 3 (6), e87, 2007
4502007
MicroRNA‐134 modulates the differentiation of mouse embryonic stem cells, where it causes post‐transcriptional attenuation of Nanog and LRH1
YMS Tay, WL Tam, YS Ang, PM Gaughwin, H Yang, W Wang, R Liu, ...
Stem cells 26 (1), 17-29, 2008
2562008
The Hippo pathway transcriptional co-activator, YAP, is an ovarian cancer oncogene
X Zhang, J George, S Deb, JL Degoutin, EA Takano, SB Fox, DDL Bowtell, ...
Oncogene 30 (25), 2810, 2011
2322011
Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study
W Sieh, M Köbel, TA Longacre, DD Bowtell, A DeFazio, MT Goodman, ...
The lancet oncology 14 (9), 853-862, 2013
2312013
Host gene expression profiling of dengue virus infection in cell lines and patients
J Fink, F Gu, L Ling, T Tolfvenstam, F Olfat, KC Chin, P Aw, J George, ...
PLoS neglected tropical diseases 1 (2), e86, 2007
2172007
Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas
D Etemadmoghadam, A Defazio, R Beroukhim, C Mermel, J George, ...
Clinical cancer research 15 (4), 1417-1427, 2009
2092009
IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer
MS Anglesio, J George, H Kulbe, M Friedlander, D Rischin, C Lemech, ...
Clinical cancer research 17 (8), 2538-2548, 2011
1832011
Genome-wide mapping of RELA (p65) binding identifies E2F1 as a transcriptional activator recruited by NF-κB upon TLR4 activation
CA Lim, F Yao, JJY Wong, J George, H Xu, KP Chiu, WK Sung, L Lipovich, ...
Molecular cell 27 (4), 622-635, 2007
1802007
Deregulation of MYCN, LIN28B and LET7 in a molecular subtype of aggressive high-grade serous ovarian cancers
Ĺ Helland, MS Anglesio, J George, PA Cowin, CN Johnstone, CM House, ...
PloS one 6 (4), e18064, 2011
1492011
Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion
HA Kenny, CY Chiang, EA White, EM Schryver, M Habis, IL Romero, ...
The Journal of clinical investigation 124 (10), 4614-4628, 2014
1332014
RCP is a human breast cancer–promoting gene with Ras-activating function
J Zhang, X Liu, A Datta, K Govindarajan, WL Tam, J Han, J George, ...
The Journal of clinical investigation 119 (8), 2171-2183, 2009
1042009
Synthetic lethality between CCNE1 amplification and loss of BRCA1
D Etemadmoghadam, BA Weir, G Au-Yeung, K Alsop, G Mitchell, ...
Proceedings of the National Academy of Sciences 110 (48), 19489-19494, 2013
1032013
Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors
MS Anglesio, JM Arnold, J George, AV Tinker, R Tothill, N Waddell, ...
Molecular cancer research 6 (11), 1678-1690, 2008
1032008
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Articles 1–20