| Cross-regulation of signaling pathways by interferon-γ: implications for immune responses and autoimmune diseases X Hu, LB Ivashkiv Immunity 31 (4), 539-550, 2009 | 991 | 2009 |
| IFN-γ suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins X Hu, PK Paik, J Chen, A Yarilina, L Kockeritz, TT Lu, JR Woodgett, ... Immunity 24 (5), 563-574, 2006 | 508 | 2006 |
| TNF activates an IRF1-dependent autocrine loop leading to sustained expression of chemokines and STAT1-dependent type I interferon–response genes A Yarilina, KH Park-Min, T Antoniv, X Hu, LB Ivashkiv Nature immunology 9 (4), 378-387, 2008 | 489 | 2008 |
| Notch–RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization H Xu, J Zhu, S Smith, J Foldi, B Zhao, AY Chung, H Outtz, J Kitajewski, ... Nature immunology 13 (7), 642-650, 2012 | 436 | 2012 |
| Crosstalk among Jak-STAT, Toll-like receptor, and ITAM-dependent pathways in macrophage activation X Hu, J Chen, L Wang, LB Ivashkiv Journal of Leucocyte Biology 82 (2), 237-243, 2007 | 332 | 2007 |
| Regulation of interferon and Toll‐like receptor signaling during macrophage activation by opposing feedforward and feedback inhibition mechanisms X Hu, SD Chakravarty, LB Ivashkiv Immunological reviews 226 (1), 41-56, 2008 | 331 | 2008 |
| Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis B Zhao, M Takami, A Yamada, X Wang, T Koga, X Hu, T Tamura, K Ozato, ... Nature medicine 15 (9), 1066-1071, 2009 | 319 | 2009 |
| Synergistic activation of inflammatory cytokine genes by interferon-γ-induced chromatin remodeling and toll-like receptor signaling Y Qiao, EG Giannopoulou, CH Chan, S Park, S Gong, J Chen, X Hu, ... Immunity 39 (3), 454-469, 2013 | 317 | 2013 |
| Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation X Su, Y Yu, Y Zhong, EG Giannopoulou, X Hu, H Liu, JR Cross, G Rätsch, ... Nature immunology 16 (8), 838-849, 2015 | 296 | 2015 |
| Integrated regulation of Toll-like receptor responses by Notch and interferon-γ pathways X Hu, AY Chung, I Wu, J Foldi, J Chen, JD Ji, T Tateya, YJ Kang, J Han, ... Immunity 29 (5), 691-703, 2008 | 278 | 2008 |
| Sensitization of IFN-γ Jak-STAT signaling during macrophage activation X Hu, C Herrero, WP Li, TT Antoniv, E Falck-Pedersen, AE Koch, ... Nature immunology 3 (9), 859-866, 2002 | 269 | 2002 |
| Role of Notch signaling in regulating innate immunity and inflammation in health and disease Y Shang, S Smith, X Hu Protein & cell 7 (3), 159-174, 2016 | 230 | 2016 |
| Inhibition of IFN-γ signaling by glucocorticoids X Hu, WP Li, C Meng, LB Ivashkiv The Journal of Immunology 170 (9), 4833-4839, 2003 | 224 | 2003 |
| Mitocytosis, a migrasome-mediated mitochondrial quality-control process H Jiao, D Jiang, X Hu, W Du, L Ji, Y Yang, X Li, T Sho, X Wang, Y Li, ... Cell 184 (11), 2896-2910. e13, 2021 | 213 | 2021 |
| Signaling by stats LB Ivashkiv, X Hu Arthritis Res Ther 6, 1-10, 2004 | 208 | 2004 |
| TNF-induced osteoclastogenesis and inflammatory bone resorption are inhibited by transcription factor RBP-J B Zhao, SN Grimes, S Li, X Hu, LB Ivashkiv Journal of Experimental Medicine 209 (2), 319-334, 2012 | 207 | 2012 |
| Tumor necrosis factor induces GSK3 kinase–mediated cross-tolerance to endotoxin in macrophages SH Park, KH Park-Min, J Chen, X Hu, LB Ivashkiv Nature immunology 12 (7), 607, 2011 | 198 | 2011 |
| The GRIP1: IRF3 interaction as a target for glucocorticoid receptor‐mediated immunosuppression MM Reily, C Pantoja, X Hu, Y Chinenov, I Rogatsky The EMBO journal 25 (1), 108-117, 2006 | 187 | 2006 |
| FcγRIII-dependent inhibition of interferon-γ responses mediates suppressive effects of intravenous immune globulin KH Park-Min, NV Serbina, W Yang, X Ma, G Krystal, BG Neel, SL Nutt, ... Immunity 26 (1), 67-78, 2007 | 185 | 2007 |
| The mevalonate pathway is a druggable target for vaccine adjuvant discovery Y Xia, Y Xie, Z Yu, H Xiao, G Jiang, X Zhou, Y Yang, X Li, M Zhao, L Li, ... Cell 175 (4), 1059-1073. e21, 2018 | 175 | 2018 |
