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David D Timm
David D Timm
Verified email at wustl.edu
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Year
Discovery and characterization of novel selective inhibitors of carbonic anhydrase IX
V Dudutiene, J Matuliene, A Smirnov, DD Timm, A Zubriene, ...
Journal of Medicinal Chemistry 57 (22), 9435-9446, 2014
922014
4-Substituted-2, 3, 5, 6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII
V Dudutienė, A Zubrienė, A Smirnov, J Gylytė, D Timm, E Manakova, ...
Bioorganic & medicinal chemistry 21 (7), 2093-2106, 2013
772013
Functionalization of fluorinated benzenesulfonamides and their inhibitory properties toward carbonic anhydrases
V Dudutienė, A Zubrienė, A Smirnov, DD Timm, J Smirnovienė, ...
ChemMedChem 10 (4), 662-687, 2015
432015
Red blood cell phenotype fidelity following glycerol cryopreservation optimized for research purposes
SC Rogers, LB Dosier, TJ McMahon, H Zhu, D Timm, H Zhang, J Herbert, ...
PLoS One 13 (12), e0209201, 2018
242018
Quantifying dynamic range in red blood cell energetics: Evidence of progressive energy failure during storage
SC Rogers, X Ge, M Brummet, X Lin, DD Timm, A d'Avignon, JR Garbow, ...
Transfusion 61 (5), 1586-1599, 2021
232021
Intrinsic Thermodynamics and Structures of 2, 4‐and 3, 4‐Substituted Fluorinated Benzenesulfonamides Binding to Carbonic Anhydrases
A Zubrienė, A Smirnov, V Dudutienė, DD Timm, J Matulienė, ...
ChemMedChem 12 (2), 161-176, 2017
232017
Intrinsic thermodynamics of high affinity inhibitor binding to recombinant human carbonic anhydrase IV
A Mickevičiūtė, DD Timm, M Gedgaudas, V Linkuvienė, Z Chen, ...
European Biophysics Journal 47, 271-290, 2018
182018
Thiazole-substituted benzenesulfonamides as inhibitors of 12 human carbonic anhydrases
E Čapkauskaitė, A Zubrienė, V Paketurytė, DD Timm, S Tumkevičius, ...
Bioorganic Chemistry 77, 534-541, 2018
112018
Combinatorial Design of Isoform‐Selective N‐Alkylated Benzimidazole‐Based Inhibitors of Carbonic Anhydrases
E Čapkauskaitė, V Linkuvienė, A Smirnov, G Milinavičiūtė, DD Timm, ...
ChemistrySelect 2 (19), 5360-5371, 2017
102017
Identification and characterization of Rvs162/Rvs167-3, a novel N-BAR heterodimer in the human fungal pathogen Candida albicans
A Gkourtsa, J van den Burg, K Strijbis, T Avula, S Bijvoets, D Timm, ...
Eukaryotic cell 14 (2), 182-193, 2015
92015
Effect of plasma processing and storage on microparticle abundance, nitric oxide scavenging, and vasoactivity
SC Rogers, FT Moynihan IV, R McDonough, DD Timm, ...
Transfusion 59 (S2), 1568-1577, 2019
82019
A pilot study on the kinetics of metabolites and microvascular cutaneous effects of nitric oxide inhalation in healthy volunteers
AR Tonelli, KS Aulak, MK Ahmed, A Hausladen, B Abuhalimeh, CJ Casa, ...
PloS one 14 (8), e0221777, 2019
42019
Sepsis Induced Red Cell Dysfunction (SiRD): Physiology and Mechanisms
X Lin, S Rogers, D Timm, P Jaya, E Melanie, J Prior, S Shivam, J Wu, ...
Blood 130, 3469, 2017
12017
Binding thermodynamics of novel selective inhibitors of Carbonic Anhydrase IX
DD Timm, A Zubriene, L Baranauskiene, V Morkunaite, J Smirnoviene, ...
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 44, S64-S64, 2015
2015
Intrinsic Thermodynamics-Structure Correlation of Carbonic Anhydrase Inhibitors
D Matulis, A Zubrienė, L Baranauskienė, A Smirnov, V Morkūnaitė, ...
Biophysical Journal 108 (2), 217a, 2015
2015
Recombinant production and inhibitor binding and stability characterization of 12 human carbonic anhydrase catalytic domains in bacterial and mammalian cells
D Matulis, V Jogaite, J Matuliene, J Kazokaite, A Kasiliauskaite, DD Timm, ...
Journal of Biotechnology, S8, 2014
2014
Thermodynamics of 4-substituted-2, 3, 5, 6-tetrafluorobenzenesulfonamides binding to carbonic anhydrase isozymes
A Zubriene, V Dudutiene, A Smirnov, D Timm, J Gylyte, E Manakova, ...
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 42, S185-S185, 2013
2013
Thermodynamics of inhibitor binding to several recombinant carbonic anhydrases isoforms
D Timm, A Zubriene, J Gylyte, V Dudutiene, A Smirnov, E Manakova, ...
FEBS JOURNAL 280, 148-148, 2013
2013
Thermodynamics of anticancer drug lead binding to target proteins by thermal shift assay
A Zubrienė, J Gylytė, V Morkūnaitė, E Kazlauskas, L Baranauskienė, ...
Epigenetics–Bench to Bedside. COST Action TD0905: Program and Abstract Book …, 2013
2013
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