| Novel Propargyl-Linked Bisubstrate Analogues as Tight-Binding Inhibitors for Nicotinamide N-Methyltransferase D Chen, L Li, K Diaz, ID Iyamu, R Yadav, N Noinaj, R Huang Journal of medicinal chemistry 62 (23), 10783-10797, 2019 | 40 | 2019 |
| Spirocyclic chromanes exhibit antiplasmodial activities and inhibit all intraerythrocytic life cycle stages BF Roberts, ID Iyamu, S Lee, E Lee, L Ayong, DE Kyle, Y Yuan, ... International Journal for Parasitology: Drugs and Drug Resistance 6 (1), 85-92, 2016 | 23 | 2016 |
| Menoctone Resistance in Malaria Parasites Is Conferred by M133I Mutations in Cytochrome b That Are Transmissible through Mosquitoes LD Blake, ME Johnson, SV Siegel, A McQueen, ID Iyamu, AK Shaikh, ... Antimicrobial Agents and Chemotherapy 61 (8), 10.1128/aac. 00689-17, 2017 | 20 | 2017 |
| Development of fluorescence polarization-based competition assay for nicotinamide N-methyltransferase ID Iyamu, R Huang Analytical biochemistry 604, 113833, 2020 | 14 | 2020 |
| A pan-inhibitor for protein arginine methyltransferase family enzymes ID Iyamu, AA Al-Hamashi, R Huang Biomolecules 11 (6), 854, 2021 | 12 | 2021 |
| Nicotinamide N-methyltransferase upregulation via the mTORC1-ATF4 pathway activation contributes to palmitate-induced lipotoxicity in hepatocytes A Griffiths, J Wang, Q Song, ID Iyamu, L Liu, J Park, Y Jiang, R Huang, ... American Journal of Physiology-Cell Physiology 321 (3), C585-C595, 2021 | 11 | 2021 |
| Discovery of a novel class of potent and selective tetrahydroindazole-based sigma-1 receptor ligands ID Iyamu, W Lv, N Malik, RK Mishra, GE Schiltz Bioorganic & medicinal chemistry 27 (9), 1824-1835, 2019 | 10 | 2019 |
| Mechanisms and inhibitors of nicotinamide N-methyltransferase ID Iyamu, R Huang RSC Medicinal Chemistry 12 (8), 1254-1261, 2021 | 9 | 2021 |
| Synthesis of a novel fused pyrrolodiazepine-based library with anti-cancer activity N Malik, ID Iyamu, KA Scheidt, GE Schiltz Tetrahedron letters 59 (15), 1513-1516, 2018 | 8 | 2018 |
| Exploring Unconventional SAM Analogues To Build Cell‐Potent Bisubstrate Inhibitors for Nicotinamide N‐Methyltransferase ID Iyamu, JZ Vilseck, R Yadav, N Noinaj, R Huang Angewandte Chemie International Edition 61 (16), e202114813, 2022 | 7 | 2022 |
| Development of Tetrahydroindazole‐Based Potent and Selective Sigma‐2 Receptor Ligands ID Iyamu, W Lv, N Malik, RK Mishra, GE Schiltz ChemMedChem 14 (13), 1248-1256, 2019 | 7 | 2019 |
| Improved cell-potent and selective peptidomimetic inhibitors of protein N-terminal methyltransferase 1 G Dong, ID Iyamu, JZ Vilseck, D Chen, R Huang Molecules 27 (4), 1381, 2022 | 6 | 2022 |
| Effects of Small Molecule Ligands on ACKR3 Receptors BE Hopkins, I Masuho, D Ren, ID Iyamu, W Lv, N Malik, KA Martemyanov, ... Molecular pharmacology 102 (3), 128-138, 2022 | 4 | 2022 |
| Discovery of a small-molecule inhibitor of the TRIP8b–HCN interaction with efficacy in neurons Y Han, ID Iyamu, MR Clutter, RK Mishra, KA Lyman, C Zhou, I Michailidis, ... Journal of Biological Chemistry 298 (7), 2022 | 4 | 2022 |
| Structure-activity and structure-property relationship studies of spirocyclic chromanes with antimalarial activity ID Iyamu, Y Zhao, PT Parvatkar, BF Roberts, DR Casandra, L Wojtas, ... Bioorganic & medicinal chemistry 57, 116629, 2022 | 4 | 2022 |
| Going beyond binary: rapid identification of protein–protein interaction modulators using a multifragment kinetic target-guided synthesis approach K Nacheva, SS Kulkarni, M Kassu, D Flanigan, A Monastyrskyi, ID Iyamu, ... Journal of Medicinal Chemistry 66 (7), 5196-5207, 2023 | 3 | 2023 |
| Structure–Activity Relationship Studies on Cell-Potent Nicotinamide N-Methyltransferase Bisubstrate Inhibitors ID Iyamu, T Zhao, R Huang Journal of Medicinal Chemistry 66 (15), 10510-10527, 2023 | 2 | 2023 |
| Comparative Study of Adenosine Analogs as Inhibitors of Protein Arginine Methyltransferases and a Clostridioides difficile-Specific DNA Adenine Methyltransferase J Zhou, Y Deng, ID Iyamu, JR Horton, D Yu, T Hajian, M Vedadi, D Rotili, ... ACS Chemical Biology 18 (4), 734-745, 2023 | 2 | 2023 |
| Target binding molecules identified by kinetic target-guided synthesis R Manetsch, KP Nacheva, DL Flanigan, NK Namelikonda, ID Iyamu, ... US Patent 10,551,389, 2020 | 2 | 2020 |
| A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors Y Deng, X Song, ID Iyamu, A Dong, J Min, R Huang Acta Pharmaceutica Sinica B 13 (12), 4893-4905, 2023 | 1 | 2023 |
