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Jacobs Kurt
Jacobs Kurt
Vrije Universiteit Brussel
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Replication fork reversal triggers fork degradation in BRCA2-defective cells
S Mijic, R Zellweger, N Chappidi, M Berti, K Jacobs, K Mutreja, S Ursich, ...
Nature communications 8 (1), 859, 2017
3432017
Pathogen-induced TLR4-TRIF innate immune signaling in hematopoietic stem cells promotes proliferation but reduces competitive fitness
H Takizawa, K Fritsch, LV Kovtonyuk, Y Saito, C Yakkala, K Jacobs, ...
Cell stem cell 21 (2), 225-240. e5, 2017
2532017
Gain of 20q11. 21 in human embryonic stem cells improves cell survival by increased expression of Bcl-xL
HT Nguyen, M Geens, A Mertzanidou, K Jacobs, C Heirman, K Breckpot, ...
Molecular human reproduction 20 (2), 168-177, 2014
1252014
Higher-density culture in human embryonic stem cells results in DNA damage and genome instability
K Jacobs, F Zambelli, A Mertzanidou, I Smolders, M Geens, HT Nguyen, ...
Stem Cell Reports 6 (3), 330-341, 2016
972016
Chromosomal meiotic segregation, embryonic developmental kinetics and DNA (hydroxy) methylation analysis consolidate the safety of human oocyte vitrification
N De Munck, L Petrussa, G Verheyen, C Staessen, Y Vandeskelde, ...
MHR: Basic science of reproductive medicine 21 (6), 535-544, 2015
652015
Low-grade chromosomal mosaicism in human somatic and embryonic stem cell populations
K Jacobs, A Mertzanidou, M Geens, H Thi Nguyen, C Staessen, C Spits
Nature communications 5 (1), 4227, 2014
422014
Chromosome constitution of human embryos generated after in vitro maturation including 3-isobutyl-1-methylxanthine in the oocyte collection medium
C Spits, L Guzman, A Mertzanidou, K Jacobs, C Ortega-Hrepich, ...
Human reproduction 30 (3), 653-663, 2015
382015
Mitotic spindle disruption in human preimplantation embryos activates the spindle assembly checkpoint but not apoptosis until Day 5 of development
K Jacobs, H Van de Velde, C De Paepe, K Sermon, C Spits
MHR: Basic science of reproductive medicine 23 (5), 321-329, 2017
332017
MCL1 is required for maintenance of intestinal homeostasis and prevention of carcinogenesis in mice
ME Healy, Y Boege, MC Hodder, F Böhm, M Malehmir, AL Scherr, ...
Gastroenterology 159 (1), 183-199, 2020
252020
Human pluripotent stem cells in regenerative medicine: where do we stand?
HT Nguyen, K Jacobs, C Spits
Reproduction 156 (5), R143-R153, 2018
162018
Pathogen-induced TLR4-TRIF innate immune signaling in hematopoietic stem cells promotes proliferation but reduces competitive fitness
H Takizawa, K Fritsch, LV Kovtonyuk, Y Saito, C Yakkala, K Jacobs, ...
Cell Stem Cell 27 (1), 177, 2020
132020
Stress-triggered hematopoietic stem cell proliferation relies on PrimPol-mediated repriming
K Jacobs, C Doerdelmann, J Krietsch, D González-Acosta, N Mathis, ...
Molecular cell 82 (21), 4176-4188. e8, 2022
122022
Genomic integrity of human embryonic stem cells: Low-grade mosaicism and the effect of culture density
K Jacobs
2015
Low-grade mosaicism in human embryonic stem cell cultures
K Jacobs, A Mertzanidou, M Geens, K Sermon, C Spits
ISSCR 11th Meeting abstract book, 2314, 2013
2013
BCL2l1 is the key driver of 20q11. 21 gains in human embryonic stem cells
HN Thi, M Geens, A Mertzanidou, K Jacobs, K Sermon, C Spits
ISSCR 11th Meeting abstract book, 2325, 2013
2013
Unraveling the selective advantage of the 20q11. 21 amplification in human embryonic stem cells
HN Thi, M Geens, A Mertzanidou, K Jacobs, K Sermon, C Spits
Halfjaarlijkse vergadering Vereniging voor Fertiliteitsstudie, 2012
2012
Starvation and overcrowding: Culture density and DNA damage in human embryonic stem cells
K Jacobs, M Geens, IJ Smolders, HN Thi, K Sermon, C Spits
Halfjaarlijkse vergadering Vereniging voor Fertiliteitsstudie, 2012
2012
Starvation and overcrowding: culture conditions and DNA damage in embryonic stem cells.
K Jacobs, C Spits, M Geens, K Sermon
12th Annual Meeting Belgian Society of Human Genetics, 2012
2012
Overcrowding and starvation: culture density and DNA damage in human embryonic stem cells
K Jacobs, C Spits, M Geens, IJ Smolders, K Sermon
Abstracts of the ISSCR 2012, 3012, 2012
2012
The Battle of Antietam: a historical study appropriate for a fifth grade classroom
KD Jacobs
California University of Pennsylvania, 1991
1991
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Articles 1–20