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Rilei Yu
Rilei Yu
Unknown affiliation
Verified email at bioch.ox.ac.uk
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Cited by
Year
ConoServer: updated content, knowledge, and discovery tools in the conopeptide database
Q Kaas, R Yu, AH Jin, S Dutertre, DJ Craik
Nucleic acids research 40 (D1), D325-D330, 2012
3662012
Determination of the α-conotoxin Vc1. 1 binding site on the α9α10 nicotinic acetylcholine receptor
R Yu, SN Kompella, DJ Adams, DJ Craik, Q Kaas
Journal of medicinal chemistry 56 (9), 3557-3567, 2013
1002013
SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells
Y Tong, D Guo, SH Lin, J Liang, D Yang, C Ma, F Shao, M Li, Q Yu, ...
Molecular Cell 81 (11), 2303-2316. e8, 2021
842021
Blockade of neuronal α7-nAChR by α-conotoxin ImI explained by computational scanning and energy calculations
R Yu, DJ Craik, Q Kaas
PLoS computational biology 7 (3), e1002011, 2011
842011
Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets
R Liu, JH Lee, J Li, R Yu, L Tan, Y Xia, Y Zheng, XL Bian, PL Lorenzi, ...
Molecular cell 81 (13), 2722-2735. e9, 2021
702021
Pathophysiology of obesity and its associated diseases
X Jin, T Qiu, L Li, R Yu, X Chen, C Li, CG Proud, T Jiang
Acta Pharmaceutica Sinica B 13 (6), 2403-2424, 2023
562023
Less is more: design of a highly stable disulfide-deleted mutant of analgesic cyclic α-conotoxin Vc1. 1
R Yu, VAL Seymour, G Berecki, X Jia, M Akcan, DJ Adams, Q Kaas, ...
Scientific reports 5 (1), 13264, 2015
552015
Novel natural angiotensin converting enzyme (ACE)-inhibitory peptides derived from sea cucumber-modified hydrolysates by adding exogenous proline and a study of their structure …
J Li, Z Liu, Y Zhao, X Zhu, R Yu, S Dong, H Wu
Marine Drugs 16 (8), 271, 2018
462018
Pharmacokinetics in Vitro and in Vivo of Two Novel Prodrugs of Oleanolic Acid in Rats and Its Hepatoprotective Effects against Liver Injury Induced by CCl4
Z Yu, W Sun, W Peng, R Yu, G Li, T Jiang
Molecular Pharmaceutics 13 (5), 1699-1710, 2016
452016
Agonist and antagonist binding in human glycine receptors
R Yu, E Hurdiss, T Greiner, R Lape, L Sivilotti, PC Biggin
Biochemistry 53 (38), 6041-6051, 2014
452014
Medicinal chemistry, pharmacology, and therapeutic potential of α-conotoxins antagonizing the α9α10 nicotinic acetylcholine receptor
X Li, HS Tae, Y Chu, T Jiang, DJ Adams, R Yu
Pharmacology & Therapeutics 222, 107792, 2021
392021
Cyclic analogues of α‐conotoxin Vc1. 1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain
J Castro, L Grundy, A Deiteren, AM Harrington, T O'Donnell, J Maddern, ...
British journal of pharmacology 175 (12), 2384-2398, 2018
392018
Boronic acid modifications enhance the anti-influenza A virus activities of novel quindoline derivatives
W Wang, R Yin, M Zhang, R Yu, C Hao, L Zhang, T Jiang
Journal of Medicinal Chemistry 60 (7), 2840-2852, 2017
342017
Discovery of DNA topoisomerase I inhibitors with low-cytotoxicity based on virtual screening from natural products
LT Xin, L Liu, CL Shao, RL Yu, FL Chen, SJ Yue, M Wang, ZL Guo, ...
Marine drugs 15 (7), 217, 2017
332017
Progress in developing MNK inhibitors
X Jin, R Yu, X Wang, CG Proud, T Jiang
European Journal of Medicinal Chemistry 219, 113420, 2021
322021
Delineation of the unbinding pathway of α-conotoxin ImI from the α7 nicotinic acetylcholine receptor
R Yu, Q Kaas, DJ Craik
The Journal of Physical Chemistry B 116 (21), 6097-6105, 2012
322012
Application of reverse docking for target prediction of marine compounds with anti-tumor activity
F Chen, Z Wang, C Wang, Q Xu, J Liang, X Xu, J Yang, C Wang, T Jiang, ...
Journal of Molecular Graphics and Modelling 77, 372-377, 2017
312017
Design, synthesis and activity of Mnk1 and Mnk2 selective inhibitors containing thieno [2, 3-d] pyrimidine scaffold
X Jin, J Merrett, S Tong, B Flower, J Xie, R Yu, S Tian, L Gao, J Zhao, ...
European journal of medicinal chemistry 162, 735-751, 2019
302019
Design of SARS-CoV-2 Mpro, PLpro dual-target inhibitors based on deep reinforcement learning and virtual screening
L Zhang, H Zhao, J Liu, L He, R Yu, C Kang
Future Medicinal Chemistry 14 (6), 393-405, 2022
292022
Molecular determinants conferring the stoichiometric-dependent activity of α-conotoxins at the human α9α10 nicotinic acetylcholine receptor subtype
R Yu, HS Tae, N Tabassum, J Shi, T Jiang, DJ Adams
Journal of Medicinal Chemistry 61 (10), 4628-4634, 2018
282018
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