The peptidomimetic CXCR4 antagonist TC14012 recruits β-arrestin to CXCR7: Roles of receptor domains S Gravel, C Malouf, PE Boulais, YA Berchiche, S Oishi, N Fujii, R Leduc, ... Journal of Biological Chemistry 285 (49), 37939-37943, 2010 | 106 | 2010 |
Molecular processes involved in B cell acute lymphoblastic leukaemia C Malouf, K Ottersbach Cellular and molecular life sciences 75, 417-446, 2018 | 104 | 2018 |
Mll-AF4 confers enhanced self-renewal and lymphoid potential during a restricted window in development NA Barrett, C Malouf, C Kapeni, WA Bacon, G Giotopoulos, ... Cell reports 16 (4), 1039-1054, 2016 | 55 | 2016 |
miR-130b and miR-128a are essential lineage-specific codrivers of t (4; 11) MLL-AF4 acute leukemia C Malouf, ETB Antunes, M O’Dwyer, H Jakobczyk, F Sahm, SL Landua, ... Blood, The Journal of the American Society of Hematology 138 (21), 2066-2092, 2021 | 31 | 2021 |
The fetal liver lymphoid-primed multipotent progenitor provides the prerequisites for the initiation of t (4; 11) MLL-AF4 infant leukemia C Malouf, K Ottersbach Haematologica 103 (12), e571, 2018 | 29 | 2018 |
Defining the fetal origin of MLL-AF4 infant leukemia highlights specific fatty acid requirements V Symeonidou, H Jakobczyk, S Bashanfer, C Malouf, F Fotopoulou, ... Cell reports 37 (4), 2021 | 22 | 2021 |
DNA damage signalling from the placenta to foetal blood as a potential mechanism for childhood leukaemia initiation E Mansell, N Zareian, C Malouf, C Kapeni, N Brown, C Badie, D Baird, ... Scientific Reports 9 (1), 4370, 2019 | 16 | 2019 |
Chronic inflammation can transform the fate of normal and mutant haematopoietic stem cells J Li, C Malouf, LA Miles, MB Willis, EM Pietras, KY King Experimental Hematology, 2023 | 9 | 2023 |
p57Kip2 regulates embryonic blood stem cells by controlling sympathoadrenal progenitor expansion C Kapeni, L Nitsche, AM Kilpatrick, NK Wilson, K Xia, ... Blood, The Journal of the American Society of Hematology 140 (5), 464-477, 2022 | 7 | 2022 |
Fetal liver Mll-AF4+ hematopoietic stem and progenitor cells respond directly to poly (I: C), but not to a single maternal immune activation C Malouf, K Ottersbach Experimental hematology 76, 49-59, 2019 | 5 | 2019 |
Translational research for bone marrow failure patients C Malouf, SJ Loughran, AC Wilkinson, A Shimamura, P Río Experimental hematology 105, 18-21, 2022 | 4 | 2022 |
Novel transcriptional targets of ETV6, a transcription factor frequently altered in childhood pre-B acute lymphoblastic leukemia C Malouf, K Lagace, C Drullion, S Langlois, J Larose, EA Kritikou, ... Cancer Sci Open Res Access 3 (1), 1-11, 2016 | 1 | 2016 |
The unconventional embryo: immune-restricted potential precedes multipotentiality C Malouf, K Ottersbach Cell Stem Cell 13 (5), 509-510, 2013 | 1 | 2013 |
The Impact of Lineage on CNS Infiltration Dynamics in Infant Leukaemia A Duguid, C Malouf, C Halsey, K Ottersbach Blood 144, 200, 2024 | | 2024 |
Leukaemia cell intrinsic and extrinsic factors cooperate to facilitate the survival and proliferation of KMT2A-rearranged B-ALL in the CNS niche. A Duguid, C Malouf, L Nitsche, N Barrett, O Smith, C Halsey, K Ottersbach bioRxiv, 2024.12. 03.626602, 2024 | | 2024 |
Targeting the dependence on PIK3C3-mTORC1 signaling in dormancy-prone breast cancer cells blunts metastasis initiation IE Elkholi, A Robert, C Malouf, H Kuasne, S Drapela, G Macleod, S Hébert, ... bioRxiv, 2023.08. 02.551681, 2023 | | 2023 |
Leukaemia in the CNS niche regulates PI3K/Akt signalling via upregulation of miR-93 in MLL-AF4+ infant leukaemia A Duguid, C Malouf, C Halsey, K Ottersbach Klinische Pädiatrie 235 (03), 0013, 2023 | | 2023 |
Exploiting somatic mutations to decipher human blood production: a natural lineage-tracing strategy M Bloom, C Malouf, A Rodriguez-Fraticelli, AC Wilkinson, VG Sankaran, ... Experimental Hematology 121, 2-5, 2023 | | 2023 |
A microRNA expression signature in infant t (4; 11) MLL-AF4+ BCP-ALL uncovers novel therapeutic targets C Malouf, A Duguid, G Camiolo, L Nitsche, H Jakobczyk, RS Kotecha, ... bioRxiv, 2023.01. 12.523775, 2023 | | 2023 |
Leukaemia and the CNS Niche: Insights on Bidirectional Communication from a Model of Infant Leukaemia A Duguid, C Malouf, V Symeonidou, C Halsey, K Ottersbach Blood 140 (Supplement 1), 3038-3039, 2022 | | 2022 |