Amyloid precursor protein regulates brain apolipoprotein E and cholesterol metabolism through lipoprotein receptor LRP1 Q Liu, CV Zerbinatti, J Zhang, HS Hoe, B Wang, SL Cole, J Herz, L Muglia, ... Neuron 56 (1), 66-78, 2007 | 439 | 2007 |
Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model C Hirata-Fukae, HF Li, HS Hoe, AJ Gray, SS Minami, K Hamada, T Niikura, ... Brain research 1216, 92-103, 2008 | 295 | 2008 |
ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo SB Dumanis, JA Tesoriero, LW Babus, MT Nguyen, JH Trotter, MJ Ladu, ... Journal of Neuroscience 29 (48), 15317-15322, 2009 | 269 | 2009 |
Interaction of reelin with amyloid precursor protein promotes neurite outgrowth HS Hoe, KJ Lee, RSE Carney, J Lee, A Markova, JY Lee, BW Howell, ... Journal of Neuroscience 29 (23), 7459-7473, 2009 | 246 | 2009 |
MiR-106b impairs cholesterol efflux and increases Aβ levels by repressing ABCA1 expression J Kim, H Yoon, CM Ramírez, SM Lee, HS Hoe, C Fernández-Hernando, ... Experimental neurology 235 (2), 476-483, 2012 | 228 | 2012 |
DAB1 and Reelin effects on amyloid precursor protein and ApoE receptor 2 trafficking and processing HS Hoe, TS Tran, Y Matsuoka, BW Howell, GW Rebeck Journal of Biological Chemistry 281 (46), 35176-35185, 2006 | 202 | 2006 |
Reelin supplementation enhances cognitive ability, synaptic plasticity, and dendritic spine density JT Rogers, I Rusiana, J Trotter, L Zhao, E Donaldson, DTS Pak, ... Learning & memory 18 (9), 558-564, 2011 | 200 | 2011 |
Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer’s disease CC Liu, CW Tsai, F Deak, J Rogers, M Penuliar, YM Sung, JN Maher, ... Neuron 84 (1), 63-77, 2014 | 195 | 2014 |
Parkin mediates beclin-dependent autophagic clearance of defective mitochondria and ubiquitinated Aβ in AD models PJ Khandelwal, AM Herman, HS Hoe, GW Rebeck, CEH Moussa Human molecular genetics 20 (11), 2091-2102, 2011 | 187 | 2011 |
Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines KJ Lee, CEH Moussa, Y Lee, Y Sung, BW Howell, RS Turner, DTS Pak, ... Neuroscience 169 (1), 344-356, 2010 | 160 | 2010 |
Ibrutinib suppresses LPS-induced neuroinflammatory responses in BV2 microglial cells and wild-type mice HY Nam, JH Nam, G Yoon, JY Lee, Y Nam, HJ Kang, HJ Cho, J Kim, ... Journal of neuroinflammation 15, 1-22, 2018 | 153 | 2018 |
Multiple pathways of apolipoprotein E signaling in primary neurons HS Hoe, DC Harris, GW Rebeck Journal of neurochemistry 93 (1), 145-155, 2005 | 149 | 2005 |
The effects of amyloid precursor protein on postsynaptic composition and activity HS Hoe, Z Fu, A Makarova, JY Lee, C Lu, L Feng, A Pajoohesh-Ganji, ... Journal of Biological Chemistry 284 (13), 8495-8506, 2009 | 148 | 2009 |
F-spondin interaction with the apolipoprotein E receptor ApoEr2 affects processing of amyloid precursor protein HS Hoe, D Wessner, U Beffert, AG Becker, Y Matsuoka, GW Rebeck Molecular and cellular biology, 2005 | 146 | 2005 |
Mercaptoacetamide-based class II HDAC inhibitor lowers Aβ levels and improves learning and memory in a mouse model of Alzheimer's disease YM Sung, T Lee, H Yoon, AM DiBattista, JM Song, Y Sohn, EI Moffat, ... Experimental neurology 239, 192-201, 2013 | 144 | 2013 |
microRNA-33 regulates ApoE lipidation and amyloid-β metabolism in the brain J Kim, H Yoon, T Horie, JM Burchett, JL Restivo, N Rotllan, CM Ramírez, ... Journal of Neuroscience 35 (44), 14717-14726, 2015 | 122 | 2015 |
Dasatinib regulates LPS-induced microglial and astrocytic neuroinflammatory responses by inhibiting AKT/STAT3 signaling KY Ryu, H Lee, H Woo, RJ Kang, KM Han, HH Park, SM Lee, JY Lee, ... Journal of neuroinflammation 16, 1-36, 2019 | 113 | 2019 |
The upside of APP at synapses HS Hoe, HK Lee, DTS Pak CNS neuroscience & therapeutics 18 (1), 47-56, 2012 | 113 | 2012 |
Requirement for Plk2 in orchestrated ras and rap signaling, homeostatic structural plasticity, and memory KJ Lee, Y Lee, A Rozeboom, JY Lee, N Udagawa, HS Hoe, DTS Pak Neuron 69 (5), 957-973, 2011 | 109 | 2011 |
Regulation of ApoE receptor proteolysis by ligand binding HS Hoe, GW Rebeck Molecular brain research 137 (1-2), 31-39, 2005 | 107 | 2005 |