Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth J Sangodkar, A Perl, R Tohme, J Kiselar, DB Kastrinsky, N Zaware, ... The Journal of clinical investigation 127 (6), 2081-2090, 2017 | 180 | 2017 |
Apigenin blocks IKKα activation and suppresses prostate cancer progression S Shukla, R Kanwal, E Shankar, M Datt, MR Chance, P Fu, ... Oncotarget 6 (31), 31216, 2015 | 89 | 2015 |
Phosphorylation of CDK9 at Ser175 Enhances HIV Transcription and Is a Marker of Activated P-TEFb in CD4+ T Lymphocytes UR Mbonye, G Gokulrangan, M Datt, C Dobrowolski, M Cooper, ... PLoS pathogens 9 (5), e1003338, 2013 | 89 | 2013 |
Dietary flavones as dual inhibitors of DNA methyltransferases and histone methyltransferases R Kanwal, M Datt, X Liu, S Gupta PloS one 11 (9), e0162956, 2016 | 57 | 2016 |
Identification of a new exosite involved in catalytic turnover by the streptokinase-plasmin activator complex during human plasminogen activation R Aneja, M Datt, B Singh, S Kumar, G Sahni Journal of biological chemistry 284 (47), 32642-32650, 2009 | 27 | 2009 |
Structural analysis of proinsulin hexamer assembly by hydroxyl radical footprinting and computational modeling JG Kiselar, M Datt, MR Chance, MA Weiss Journal of Biological Chemistry 286 (51), 43710-43716, 2011 | 26 | 2011 |
Role of the 88–97 loop in plasminogen activation by streptokinase probed through site-specific mutagenesis S Yadav, M Datt, B Singh, G Sahni Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1784 (9), 1310-1318, 2008 | 24 | 2008 |
Evolutionary and structural annotation of disease-associated mutations in human aminoacyl-tRNA synthetases M Datt, A Sharma BMC genomics 15, 1-20, 2014 | 23 | 2014 |
Novel and unique domains in aminoacyl-tRNA synthetases from human fungal pathogens Aspergillus niger, Candida albicans and Cryptococcus neoformans M Datt, A Sharma BMC genomics 15, 1-17, 2014 | 20 | 2014 |
Multiple exosites distributed across the three domains of streptokinase co-operate to generate high catalytic rates in the streptokinase–plasmin activator complex R Aneja, M Datt, S Yadav, G Sahni Biochemistry 52 (49), 8957-8968, 2013 | 20 | 2013 |
Conformational landscapes for KMSKS loop in tyrosyl-tRNA synthetases M Datt, A Sharma Journal of structural and functional genomics 15, 45-61, 2014 | 18 | 2014 |
Replacement of the active surface of a thermophile protein by that of a homologous mesophile protein through structure-guided ‘protein surface grafting’ D Kapoor, V Kumar, SK Chandrayan, S Ahmed, S Sharma, M Datt, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1784 (11), 1771-1776, 2008 | 18 | 2008 |
A single-amino-acid substitution in the C terminus of PhoP determines DNA-binding specificity of the virulence-associated response regulator from Mycobacterium tuberculosis AK Das, A Pathak, A Sinha, M Datt, B Singh, S Karthikeyan, D Sarkar Journal of molecular biology 398 (5), 647-656, 2010 | 17 | 2010 |
Molecular cloning, characterization, and engineering of xylitol dehydrogenase from Debaryomyces hansenii D Biswas, M Datt, M Aggarwal, AK Mondal Applied microbiology and biotechnology 97, 1613-1623, 2013 | 15 | 2013 |
Equilibrium binding and kinetic characterization of putative tetracycline repressor family transcription regulator Fad35R from Mycobacterium tuberculosis S Anand, V Singh, AK Singh, M Mittal, M Datt, B Subramani, S Kumaran The FEBS journal 279 (17), 3214-3228, 2012 | 15 | 2012 |
Genome-Wide Collation of the Plasmodium falciparum WDR Protein Superfamily Reveals Malarial Parasite-Specific Features P Chahar, M Kaushik, SS Gill, SK Gakhar, N Gopalan, M Datt, A Sharma, ... PLoS One 10 (6), e0128507, 2015 | 14 | 2015 |
Identification through combinatorial random and rational mutagenesis of a substrate-interacting exosite in the γ domain of streptokinase S Yadav, R Aneja, P Kumar, M Datt, S Sinha, G Sahni Journal of biological chemistry 286 (8), 6458-6469, 2011 | 12 | 2011 |
Cys-Gly specific dipeptidase Dug1p from S. cerevisiae binds promiscuously to di-, tri-, and tetra-peptides: Peptide–protein interaction, homology modeling, and activity studies … H Kaur, M Datt, MK Ekka, M Mittal, AK Singh, S Kumaran Biochimie 93 (2), 175-186, 2011 | 12 | 2011 |
Cloning and characterization of thermotolerant xylitol dehydrogenases from yeast Pichia angusta D Biswas, M Datt, K Ganesan, AK Mondal Applied microbiology and biotechnology 88, 1311-1320, 2010 | 12 | 2010 |
Safranal inhibits NLRP3 inflammasome activation by preventing ASC oligomerization M Gupta, A Wani, AU Ahsan, M Ali, P Chibber, S Singh, SK Digra, M Datt, ... Toxicology and Applied Pharmacology 423, 115582, 2021 | 11 | 2021 |