Andrew Frelinger
Andrew Frelinger
Center for Platelet Research Studies, Boston Children's Hospital
Verified email at - Homepage
Cited by
Cited by
Prasugrel compared with high loading-and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel …
SD Wiviott, D Trenk, AL Frelinger, M O’Donoghue, FJ Neumann, ...
Circulation 116 (25), 2923-2932, 2007
AD Michelson, M Cattaneo, A Frelinger, P Newman
Academic press, 2019
Ligands “activate” integrin αIIbβ3 (platelet GPIIb-IIIa)
X Du, EF Plow, AL Frelinger III, TE O'Toole, JC Loftus, MH Ginsberg
Cell 65 (3), 409-416, 1991
A β3 Integrin Mutation Abolishes Ligand Binding and Alters Divalent Cation-Dependent Conformation
JC Loftus, TE O'Toole, EF Plow, A Glass, AL Frelinger III, MH Ginsberg
Science 249 (4971), 915-918, 1990
Circulating monocyte-platelet aggregates are an early marker of acute myocardial infarction
MI Furman, MR Barnard, LA Krueger, ML Fox, EA Shilale, DM Lessard, ...
Journal of the American College of Cardiology 38 (4), 1002-1006, 2001
Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease
JL Mega, W Hochholzer, AL Frelinger, MJ Kluk, DJ Angiolillo, ...
Jama 306 (20), 2221-2228, 2011
Evaluation of platelet function by flow cytometry
AD Michelson, MR Barnard, LA Krueger, AL Frelinger III, MI Furman
Methods 21 (3), 259-270, 2000
Monoclonal antibodies to ligand-occupied conformers of integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) alter receptor affinity, specificity, and function.
AL Frelinger 3rd, XP Du, EF Plow, MH Ginsberg
Journal of Biological Chemistry 266 (26), 17106-17111, 1991
Platelet physiology
T Gremmel, AL Frelinger III, AD Michelson
Seminars in thrombosis and hemostasis 42 (03), 191-204, 2016
Selective inhibition of integrin function by antibodies specific for ligand-occupied receptor conformers.
AL Frelinger 3rd, I Cohen, EF Plow, MA Smith, J Roberts, SC Lam, ...
Journal of Biological Chemistry 265 (11), 6346-6352, 1990
Residual arachidonic acid–induced platelet activation via an adenosine diphosphate–dependent but cyclooxygenase-1–and cyclooxygenase-2–independent pathway: a 700-patient study …
AL Frelinger III, MI Furman, MD Linden, Y Li, ML Fox, MR Barnard, ...
Circulation 113 (25), 2888-2896, 2006
Occupancy of an adhesive glycoprotein receptor modulates expression of an antigenic site involved in cell adhesion.
AL Frelinger, SC Lam, EF Plow, MA Smith, JC Loftus, MH Ginsberg
Journal of Biological Chemistry 263 (25), 12397-12402, 1988
Pharmacodynamic assessment of platelet inhibition by prasugrel vs. clopidogrel in the TRITON-TIMI 38 trial
AD Michelson, AL Frelinger III, E Braunwald, WE Downey, DJ Angiolillo, ...
European heart journal 30 (14), 1753-1763, 2009
Current options in platelet function testing
AD Michelson, AL Frelinger III, MI Furman
The American journal of cardiology 98 (10), S4-S10, 2006
Measuring antiplatelet drug effects in the laboratory
P Harrison, AL Frelinger III, MI Furman, AD Michelson
Thrombosis research 120 (3), 323-336, 2007
Clopidogrel Pharmacokinetics and Pharmacodynamics Vary Widely Despite Exclusion or Control of Polymorphisms (CYP2C19, ABCB1, PON1), Noncompliance …
AL Frelinger, DL Bhatt, RD Lee, DJ Mulford, J Wu, S Nudurupati, A Nigam, ...
Journal of the American College of Cardiology 61 (8), 872-879, 2013
Analysis of platelet aggregation disorders based on flow cytometric analysis of membrane glycoprotein IIb-IIIa with conformation-specific monoclonal antibodies
MH Ginsberg, AL Frelinger, SC Lam, J Forsyth, R McMillan, EF Plow, ...
A pharmacodynamic comparison of prasugrel vs. high-dose clopidogrel in patients with type 2 diabetes mellitus and coronary artery disease: results of the Optimizing anti …
DJ Angiolillo, JJ Badimon, JF Saucedo, AL Frelinger, AD Michelson, ...
European heart journal 32 (7), 838-846, 2011
The human endogenous circadian system causes greatest platelet activation during the biological morning independent of behaviors
FAJL Scheer, AD Michelson, AL Frelinger III, H Evoniuk, EE Kelly, ...
PloS one 6 (9), e24549, 2011
Increased platelet inhibition after switching from maintenance clopidogrel to prasugrel in patients with acute coronary syndromes: results of the SWAP (SWitching Anti Platelet …
DJ Angiolillo, JF Saucedo, R DeRaad, AL Frelinger, PA Gurbel, ...
Journal of the American College of Cardiology 56 (13), 1017-1023, 2010
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