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Kovela Satish
Kovela Satish
Principal Investigator
Verified email at purdue.edu - Homepage
Title
Cited by
Cited by
Year
Potent HIV-1 Protease Inhibitors Containing Carboxylic and Boronic Acids: Effect on Enzyme Inhibition and Antiviral Activity and Protein-ligand X-ray Structural Studies
AK Ghosh, Z Xia, S Kovela, WL Robinson, ME Johnson, DW Kneller, ...
Chemmedchem 14 (18), 2019
150*2019
Nazarov Cyclization of Divinyl and Arylvinyl Epoxides: Application in the Synthesis of Resveratrol‐Based Natural Products
G Sudhakar, K Satish
Chemistry–A European Journal 21 (17), 6475-6480, 2015
412015
Design of Highly Potent, Dual‐Acting and Central‐Nervous‐System‐Penetrating HIV‐1 Protease Inhibitors with Excellent Potency against Multidrug‐Resistant HIV‐1 Variants
AK Ghosh, KV Rao, PR Nyalapatla, S Kovela, M Brindisi, HL Osswald, ...
ChemMedChem 13 (8), 803-815, 2018
392018
Design and Synthesis of Highly Potent HIV‑1 Protease Inhibitors Containing Tricyclic Fused Ring Systems as Novel P2 Ligands: Structure−Activity Studies, Biological and X‑ray …
HM Arun K. Ghosh, Prasanth R. Nyalapatla, Satish Kovela, Kalapala ...
J. Med. Chem.DOI: 10.1021/acs.jmedchem.8b00298, 2018
33*2018
Structure-Based Design of Highly Potent HIV‑1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X‑ray Structural Studies
HM Arun K. Ghosh,* Satish Kovela, Heather L. Osswald, Masayuki Amano, Manabu ...
J. Med. Chem, 2020
212020
Enantioselective synthesis of a cyclopropane derivative of spliceostatin A and evaluation of bioactivity
AK Ghosh, GC Reddy, S Kovela, N Relitti, VK Urabe, BE Prichard, ...
Organic letters 20 (22), 7293-7297, 2018
212018
Total synthesis and absolute configuration of curvularides AE
G Sudhakar, K Satish, J Raghavaiah
The Journal of Organic Chemistry 77 (22), 10010-10020, 2012
202012
Highly Selective and Potent Human β‐Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X‐ray Structure and Structure–Activity Relationship Studies
AK Ghosh, M Brindisi, YC Yen, EK Lendy, S Kovela, EL Cárdenas, ...
ChemMedChem 14 (5), 545-560, 2019
192019
Chloropyridinyl esters of nonsteroidal anti-inflammatory agents and related derivatives as potent SARS-CoV-2 3CL protease inhibitors
AK Ghosh, D Shahabi, M Yadav, S Kovela, BJ Anson, EK Lendy, ...
Molecules 26 (19), 5782, 2021
92021
Potent HIV-1 protease inhibitors incorporating squaramide-derived P2 ligands: Design, synthesis, and biological evaluation
AK Ghosh, JN Williams, S Kovela, J Takayama, HM Simpson, DE Walters, ...
Bioorganic & medicinal chemistry letters 29 (18), 2565-2570, 2019
92019
Cytotoxic diterpenoid quinonemethides from the roots of Pygmacopremna herbacea
K Satish, M Vishnuvardhan, VL Nayak, G Srihari, M Subrahamanyam, ...
Bioorganic & medicinal chemistry letters 21 (15), 4581-4584, 2011
72011
Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors with P2-carboxamide functionalities
AK Ghosh, A Grillo, J Raghavaiah, S Kovela, ME Johnson, DW Kneller, ...
ACS Medicinal Chemistry Letters 11 (10), 1965-1972, 2020
62020
SARS-CoV-2 papain-like protease (PLpro) inhibitory and antiviral activity of small molecule derivatives for drug leads
AK Ghosh, D Shahabi, MEC Imhoff, S Kovela, A Sharma, S Hattori, ...
Bioorganic & Medicinal Chemistry Letters 96, 129489, 2023
42023
Two new diterpenoids from the roots of Pygmacopremna herbacea
K Satish, G Srihari, G Sudhakar, K Narsimha, TP Rao, MM Murthy
Phytochemistry letters 12, 129-132, 2015
42015
Two new diterpenoids from the root nodules of Pygmacopremna herbacea (Roxb.) Moldenke
G Srihari, M Vishnuvardhan, K Satish, M Subrahamanyam, TV Raju, ...
Phytochemistry letters 4 (2), 109-112, 2011
42011
Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors incorporating aminothiochromane and aminotetrahydronaphthalene carboxamide derivatives as the P2 ligands
AK Ghosh, RD Jadhav, H Simpson, S Kovela, H Osswald, J Agniswamy, ...
European journal of medicinal chemistry 160, 171-182, 2018
32018
Design, Synthesis and X‐Ray Structural Studies of Potent HIV‐1 Protease Inhibitors Containing C‐4 Substituted Tricyclic Hexahydro‐Furofuran Derivatives as P2 Ligands
AK Ghosh, S Kovela, A Sharma, D Shahabi, AK Ghosh, DR Hopkins, ...
ChemMedChem 17 (9), e202200058, 2022
22022
Asymmetric Diels–Alder reaction of 3-(acyloxy) acryloyl oxazolidinones: optically active synthesis of a high-affinity ligand for potent HIV-1 protease inhibitors
AK Ghosh, A Grillo, S Kovela, M Brindisi
RSC advances 9 (71), 41755-41763, 2019
22019
Exploration of imatinib and nilotinib-derived templates as the P2-Ligand for HIV-1 protease inhibitors: Design, synthesis, protein X-ray structural studies, and biological …
AK Ghosh, JL Mishevich, S Kovela, R Shaktah, AK Ghosh, M Johnson, ...
European journal of medicinal chemistry 255, 115385, 2023
12023
Total Synthesis of Curvularides AE NazarovCyclization of Dienyl Epoxides Synthesis of Resveratrol Based Natural Products and phytochemical studies on Pygmacopremna Herbacea
K Satish
Hyderabad, 2015
12015
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