Potent HIV-1 Protease Inhibitors Containing Carboxylic and Boronic Acids: Effect on Enzyme Inhibition and Antiviral Activity and Protein-ligand X-ray Structural Studies AK Ghosh, Z Xia, S Kovela, WL Robinson, ME Johnson, DW Kneller, ... Chemmedchem 14 (18), 2019 | 150* | 2019 |
Nazarov Cyclization of Divinyl and Arylvinyl Epoxides: Application in the Synthesis of Resveratrol‐Based Natural Products G Sudhakar, K Satish Chemistry–A European Journal 21 (17), 6475-6480, 2015 | 41 | 2015 |
Design of Highly Potent, Dual‐Acting and Central‐Nervous‐System‐Penetrating HIV‐1 Protease Inhibitors with Excellent Potency against Multidrug‐Resistant HIV‐1 Variants AK Ghosh, KV Rao, PR Nyalapatla, S Kovela, M Brindisi, HL Osswald, ... ChemMedChem 13 (8), 803-815, 2018 | 39 | 2018 |
Design and Synthesis of Highly Potent HIV‑1 Protease Inhibitors Containing Tricyclic Fused Ring Systems as Novel P2 Ligands: Structure−Activity Studies, Biological and X‑ray … HM Arun K. Ghosh, Prasanth R. Nyalapatla, Satish Kovela, Kalapala ... J. Med. Chem.DOI: 10.1021/acs.jmedchem.8b00298, 2018 | 33* | 2018 |
Structure-Based Design of Highly Potent HIV‑1 Protease Inhibitors Containing New Tricyclic Ring P2-Ligands: Design, Synthesis, Biological, and X‑ray Structural Studies HM Arun K. Ghosh,* Satish Kovela, Heather L. Osswald, Masayuki Amano, Manabu ... J. Med. Chem, 2020 | 21 | 2020 |
Enantioselective synthesis of a cyclopropane derivative of spliceostatin A and evaluation of bioactivity AK Ghosh, GC Reddy, S Kovela, N Relitti, VK Urabe, BE Prichard, ... Organic letters 20 (22), 7293-7297, 2018 | 21 | 2018 |
Total synthesis and absolute configuration of curvularides AE G Sudhakar, K Satish, J Raghavaiah The Journal of Organic Chemistry 77 (22), 10010-10020, 2012 | 20 | 2012 |
Highly Selective and Potent Human β‐Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X‐ray Structure and Structure–Activity Relationship Studies AK Ghosh, M Brindisi, YC Yen, EK Lendy, S Kovela, EL Cárdenas, ... ChemMedChem 14 (5), 545-560, 2019 | 19 | 2019 |
Chloropyridinyl esters of nonsteroidal anti-inflammatory agents and related derivatives as potent SARS-CoV-2 3CL protease inhibitors AK Ghosh, D Shahabi, M Yadav, S Kovela, BJ Anson, EK Lendy, ... Molecules 26 (19), 5782, 2021 | 9 | 2021 |
Potent HIV-1 protease inhibitors incorporating squaramide-derived P2 ligands: Design, synthesis, and biological evaluation AK Ghosh, JN Williams, S Kovela, J Takayama, HM Simpson, DE Walters, ... Bioorganic & medicinal chemistry letters 29 (18), 2565-2570, 2019 | 9 | 2019 |
Cytotoxic diterpenoid quinonemethides from the roots of Pygmacopremna herbacea K Satish, M Vishnuvardhan, VL Nayak, G Srihari, M Subrahamanyam, ... Bioorganic & medicinal chemistry letters 21 (15), 4581-4584, 2011 | 7 | 2011 |
Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors with P2-carboxamide functionalities AK Ghosh, A Grillo, J Raghavaiah, S Kovela, ME Johnson, DW Kneller, ... ACS Medicinal Chemistry Letters 11 (10), 1965-1972, 2020 | 6 | 2020 |
SARS-CoV-2 papain-like protease (PLpro) inhibitory and antiviral activity of small molecule derivatives for drug leads AK Ghosh, D Shahabi, MEC Imhoff, S Kovela, A Sharma, S Hattori, ... Bioorganic & Medicinal Chemistry Letters 96, 129489, 2023 | 4 | 2023 |
Two new diterpenoids from the roots of Pygmacopremna herbacea K Satish, G Srihari, G Sudhakar, K Narsimha, TP Rao, MM Murthy Phytochemistry letters 12, 129-132, 2015 | 4 | 2015 |
Two new diterpenoids from the root nodules of Pygmacopremna herbacea (Roxb.) Moldenke G Srihari, M Vishnuvardhan, K Satish, M Subrahamanyam, TV Raju, ... Phytochemistry letters 4 (2), 109-112, 2011 | 4 | 2011 |
Design, synthesis, and X-ray studies of potent HIV-1 protease inhibitors incorporating aminothiochromane and aminotetrahydronaphthalene carboxamide derivatives as the P2 ligands AK Ghosh, RD Jadhav, H Simpson, S Kovela, H Osswald, J Agniswamy, ... European journal of medicinal chemistry 160, 171-182, 2018 | 3 | 2018 |
Design, Synthesis and X‐Ray Structural Studies of Potent HIV‐1 Protease Inhibitors Containing C‐4 Substituted Tricyclic Hexahydro‐Furofuran Derivatives as P2 Ligands AK Ghosh, S Kovela, A Sharma, D Shahabi, AK Ghosh, DR Hopkins, ... ChemMedChem 17 (9), e202200058, 2022 | 2 | 2022 |
Asymmetric Diels–Alder reaction of 3-(acyloxy) acryloyl oxazolidinones: optically active synthesis of a high-affinity ligand for potent HIV-1 protease inhibitors AK Ghosh, A Grillo, S Kovela, M Brindisi RSC advances 9 (71), 41755-41763, 2019 | 2 | 2019 |
Exploration of imatinib and nilotinib-derived templates as the P2-Ligand for HIV-1 protease inhibitors: Design, synthesis, protein X-ray structural studies, and biological … AK Ghosh, JL Mishevich, S Kovela, R Shaktah, AK Ghosh, M Johnson, ... European journal of medicinal chemistry 255, 115385, 2023 | 1 | 2023 |
Total Synthesis of Curvularides AE NazarovCyclization of Dienyl Epoxides Synthesis of Resveratrol Based Natural Products and phytochemical studies on Pygmacopremna Herbacea K Satish Hyderabad, 2015 | 1 | 2015 |