Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations DM Rissin, CW Kan, TG Campbell, SC Howes, DR Fournier, L Song, ... Nature biotechnology 28 (6), 595-599, 2010 | 1961 | 2010 |
The Simoa HD-1 analyzer: a novel fully automated digital immunoassay analyzer with single-molecule sensitivity and multiplexing DH Wilson, DM Rissin, CW Kan, DR Fournier, T Piech, TG Campbell, ... Journal of laboratory automation 21 (4), 533-547, 2016 | 393 | 2016 |
Simultaneous detection of single molecules and singulated ensembles of molecules enables immunoassays with broad dynamic range DM Rissin, DR Fournier, T Piech, CW Kan, TG Campbell, L Song, ... Analytical chemistry 83 (6), 2279-2285, 2011 | 248 | 2011 |
Hypoxia due to cardiac arrest induces a time-dependent increase in serum amyloid β levels in humans H Zetterberg, E Mörtberg, L Song, L Chang, GK Provuncher, PP Patel, ... PloS one 6 (12), e28263, 2011 | 182 | 2011 |
Multiplexed single molecule immunoassays DM Rissin, CW Kan, L Song, AJ Rivnak, MW Fishburn, Q Shao, T Piech, ... Lab on a Chip 13 (15), 2902-2911, 2013 | 161 | 2013 |
Isolation and detection of single molecules on paramagnetic beads using sequential fluid flows in microfabricated polymer array assemblies CW Kan, AJ Rivnak, TG Campbell, T Piech, DM Rissin, M Mösl, A Peterça, ... Lab on a Chip 12 (5), 977-985, 2012 | 128 | 2012 |
A fully-automated, six-plex single molecule immunoassay for measuring cytokines in blood AJ Rivnak, DM Rissin, CW Kan, L Song, MW Fishburn, T Piech, ... Journal of immunological methods 424, 20-27, 2015 | 97 | 2015 |
Digital enzyme-linked immunosorbent assays with sub-attomolar detection limits based on low numbers of capture beads combined with high efficiency bead analysis CW Kan, CI Tobos, DM Rissin, AD Wiener, RE Meyer, DM Svancara, ... Lab on a Chip 20 (12), 2122-2135, 2020 | 57 | 2020 |
Single molecule measurements of tumor necrosis factor α and interleukin-6 in the plasma of patients with Crohn's disease L Song, DW Hanlon, L Chang, GK Provuncher, CW Kan, TG Campbell, ... Journal of immunological methods 372 (1-2), 177-186, 2011 | 57 | 2011 |
Simple diffusion-constrained immunoassay for p24 protein with the sensitivity of nucleic acid amplification for detecting acute HIV infection L Chang, L Song, DR Fournier, CW Kan, PP Patel, EP Ferrell, BA Pink, ... Journal of virological methods 188 (1-2), 153-160, 2013 | 49 | 2013 |
The optics inside an automated single molecule array analyzer W McGuigan, DR Fournier, GW Watson, L Walling, B Gigante, DC Duffy, ... Advanced Biomedical and Clinical Diagnostic Systems XII 8935, 133-145, 2014 | 8 | 2014 |
Ultra-sensitive detection of molecules or particles using beads or other capture objects DC Duffy, DM Rissin, DR Walt, D Fournier, CW Kan US Patent App. 16/906,257, 2020 | 4 | 2020 |
Improving the accuracy, robustness, and dynamic range of digital bead assays J Zhang, AD Wiener, RE Meyer, CW Kan, DM Rissin, B Kolluru, C George, ... Analytical Chemistry 95 (22), 8613-8620, 2023 | 1 | 2023 |
Ultrasensitive multiplexed chemiluminescent enzyme-linked immunosorbent assays in 384-well plates T Chen, A Ubaidu, S Douglas, S Carranza, A Wong, CW Kan, DC Duffy Journal of Immunological Methods 508, 113311, 2022 | 1 | 2022 |
Systems, devices, and methods for ultra-sensitive detection of molecules or particles D Fournier, T Campbell, CW Kan, J Lawson, A Rivnak, M Kagan, ... US Patent App. 17/396,264, 2022 | 1 | 2022 |
Digital enzyme-linked immunosorbent assays with subfemtomolar detection limits in serum DM Rissin, CW Kan, TG Campbell, SC Howes, DR Fournier, L Song, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 240, 2010 | 1 | 2010 |
Reducing the cost and complexity of imaging for digital protein detection in point-of-care diagnostics RE Meyer, AD Wiener, J Zhang, R Manning, CW Kan, B Kolluru, ... Optical Methods for Inspection, Characterization, and Imaging of …, 2023 | | 2023 |
Methods and systems related to highly sensitive assays and delivering capture objects DC Duffy, N Collier, CW Kan, CI Tobos, DM Rissin, AD Wiener, R Meyer, ... US Patent App. 17/965,199, 2023 | | 2023 |
Development of AccuPSATM, a novel digital immunoassay for sub-femtomolar measurement of PSA in post radical prostatectomy patients DH Wilson, DC Duffy, DM Rissin, CW Kan, TG Campbell, SC Howes, ... Biotechnology 28, 595-599, 2010 | | 2010 |