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manoj pothuganti
manoj pothuganti
Scientist , Invitro biology, Glenmark pharmaceutical limited
Verified email at glenmarkpharma.com
Title
Cited by
Cited by
Year
Structure of cyclin-dependent kinase 2 (CDK2) in complex with the specific and potent inhibitor CVT-313
SR Talapati, V Nataraj, M Pothuganti, S Gore, M Ramachandra, T Antony, ...
Acta Crystallographica Section F: Structural Biology Communications 76 (8 …, 2020
72020
Potent and selective inhibition of CDK7 by novel covalent inhibitors
LK Satyam, R Poddutoori, S Mukherjee, S Marappan, S Gopinath, ...
Cancer Research 76 (14_Supplement), 3070-3070, 2016
42016
Preclinical profile of novel and potent small molecule inhibitors of PARG
S Patra, M Pothuganti, G Kummari, V Sankeshi, J Kapaka, N Karche, ...
Cancer Research 84 (6_Supplement), 7112-7112, 2024
2024
Preclinical profile of novel and potent small molecule inhibitors of KIF18A inhibitors in chromosomally unstable solid tumor lines
S Petra, M Pothuganti, N Karche, G Gudade, V Sankeshi, G Kummari, ...
MOLECULAR CANCER THERAPEUTICS 22 (12), 2023
2023
Abstract A024: Preclinical profile of novel and potent small molecule inhibitors of KIF18A inhibitors in chromosomally unstable solid tumor lines
S Patra, M Pothuganti, N Karche, G Gudade, V Sankeshi, G Kummari, ...
Molecular Cancer Therapeutics 22 (12_Supplement), A024-A024, 2023
2023
Abstract A099: Best in class, potent, SOS1 inhibitors demonstrate single agent activity in preclinical models of KRAS driven tumors
B Lakhavath, M Pothuganti, G Kummari, H Pathange, R Sekar, ...
Molecular Cancer Therapeutics 22 (12_Supplement), A099-A099, 2023
2023
35P SAT-122: A potential first-in-class, potent, small-molecule disruptor of RAD51-BRCA2, attenuates RAD51 foci formation and tumor progression in preclinical models
S Patra, M Pothuganti, V Sankeshi, H Pathange, K Soumyajit, ...
Annals of Oncology 34, S197, 2023
2023
Structural and binding studies of cyclin‐dependent kinase 2 with NU6140 inhibitor
SR Talapati, M Goyal, V Nataraj, M Pothuganti, S Gore, M Ramachandra, ...
Chemical Biology & Drug Design 98 (5), 857-868, 2021
2021
Discovery and preclinical evaluation of a novel covalent inhibitor of FABP5 for cancer therapy
D Chikkanna, LK Satyam, SK Pnaigrahi, V Khairnar, M Pothuganti, ...
Cancer Research 81 (13_Supplement), 1266-1266, 2021
2021
Anti-tumor efficacy of SMARCA degraders in pre-clinical models of cancer
LK Satyam, S Sasmal, MK Pothuganti, S MR, A Ettam, S Nunna, ...
Cancer Research 79 (13_Supplement), 3844-3844, 2019
2019
In vivo anti-tumor efficacy with a dual degrader of SMARCA2 and SMARCA4
G Daginakatte, S Sasmal, LK Satyam, MK Pothuganti, A Ettam, S Nunna, ...
EUROPEAN JOURNAL OF CANCER 103, E134-E134, 2018
2018
Abstract LB-258: Identification of SMARCA2/4 degraders for the treatment of SMARCA4-mutant and other cancers
S Sasmal, LK Satyam, MK Pothuganti, A Ettam, S Nunna, MA Shareef, ...
Cancer Research 78 (13_Supplement), LB-258-LB-258, 2018
2018
Abstract B164: Identification of a novel highly selective and orally bioavailable preclinical candidate for CDK7 covalent inhibition
R Poddutoori, L Khare Satyam, S Mukherjee, S Marappan, S Gopinath, ...
Molecular Cancer Therapeutics 17 (1_Supplement), B164-B164, 2018
2018
Abstract LB-317: Identification of a novel preclinical candidate for CDK7 inhibition
LK Satyam, R Poddutoori, S Mukherjee, S Marappan, S Gopinath, ...
Cancer Research 77 (13_Supplement), LB-317-LB-317, 2017
2017
Potent small molecule compounds that selectively inhibit proliferation of ABC-DLBCL cell lines
LK Satyam, D Chikkanna, V Khairnar, M Pothuganti, S Panigrahi, ...
Cancer Research 77 (13_Supplement), 5108-5108, 2017
2017
Abstract C190: Potent and selective inhibition of CDK7 by novel covalent inhibitors
R Poddutoori, LK Satyam, G Daginakatte, S Mukherjee, S Marappan, ...
Molecular Cancer Therapeutics 14 (12_Supplement_2), C190-C190, 2015
2015
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