Mahmoud Al-Sha'er
Mahmoud Al-Sha'er
Zarqa University-Faculty of Pharmacy
Verified email at zu.edu.jo - Homepage
TitleCited byYear
Elaborate ligand-based modeling reveals new nanomolar heat shock protein 90α inhibitors
MA Al-Sha’er, MO Taha
Journal of chemical information and modeling 50 (9), 1706-1723, 2010
472010
Discovery of novel CDK1 inhibitors by combining pharmacophore modeling, QSAR analysis and in silico screening followed by in vitro bioassay
MA Al-Sha’er, MO Taha
European journal of medicinal chemistry 45 (9), 4316-4330, 2010
402010
Discovery of novel urokinase plasminogen activator (uPA) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis
MA Al-Sha’er, MA Khanfar, MO Taha
Journal of molecular modeling 20 (1), 2080, 2014
242014
Application of docking-based comparative intermolecular contacts analysis to validate Hsp90α docking studies and subsequent in silico screening for inhibitors
MA Al-Sha’er, MO Taha
Journal of molecular modeling 18 (11), 4843-4863, 2012
242012
Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3Kγ) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis
MO Taha, MA Al-Sha'er, MA Khanfar, AH Al-Nadaf
European journal of medicinal chemistry 84, 454-465, 2014
162014
Elaborate ligand-based modeling reveal new migration inhibitory factor inhibitors
MA Al-Sha’er, S VanPatten, Y Al-Abed, MO Taha
Journal of Molecular Graphics and Modelling 42, 104-114, 2013
142013
Rational exploration of new pyridinium-based HSP90α inhibitors tailored to thiamine structure
MA Al-Sha’er, MO Taha
Medicinal Chemistry Research 21 (4), 487-510, 2012
132012
Some sulfonamide drugs inhibit ATPase activity of heat shock protein 90: investigation by docking simulation and experimental validation
GA Sheikha, MA Al-Sha’er, MO Taha
Journal of enzyme inhibition and medicinal chemistry 26 (5), 603-609, 2011
92011
Evaluation of novel Akt1 inhibitors as anticancer agents using virtual co-crystallized pharmacophore generation
MA Al-Sha’er, I Mansi, I Almazari, N Hakooz
Journal of Molecular Graphics and Modelling 62, 213-225, 2015
62015
Design, synthesis, and biological evaluation of sulfonic acid ester and benzenesulfonamide derivatives as potential CETP inhibitors
RA Khalaf, GA Sheikha, M Al-Sha’er, G Albadawi, M Taha
Medicinal Chemistry Research 21 (11), 3669-3680, 2012
62012
Discovery of new heat shock protein 90 inhibitors using virtual co-crystallized pharmacophore generation
MA Al-Sha'er, I Mansi, M Khanfar, A Abudayyh
Journal of enzyme inhibition and medicinal chemistry 31 (sup4), 64-77, 2016
52016
Docking and pharmacophore mapping of halogenated pyridinium derivatives on heat shock protein 90
MA Al-Sha'er, I Mansi, N Hakooz
Journal of Chemical and Pharmaceutical Research 7 (4), 103-112, 2015
32015
Evaluation of antimicrobial activities of synthesized pyridinium derivatives
MA Al-Sha’er
Pharma Chem 6, 261-291, 2014
32014
Design, Synthesis and Biological Evaluation of N4-Sulfonamido-Succinamic, Phthalamic, Acrylic and Benzoyl Acetic Acid Derivatives as Potential DPP IV Inhibitors
RA Khalaf, GA Sheikha, M Al-Sha'er, M Taha
The open medicinal chemistry journal 7, 39, 2013
32013
1-[2-Substituted ethyl]-2-methyl-5-nitroimidazole derivatives, synthesis and antibacterial activities
MA Al-Sha’er, I Mansi, N Hakooz
Der Pharma Chem. 5, 156-162, 2013
32013
Ligand-based modeling of Akt3 lead to potent dual Akt1/Akt3 inhibitor
MA Al-Sha’er, MO Taha
Journal of Molecular Graphics and Modelling 83, 153-166, 2018
22018
Discovery of novel potent nuclear factor kappa‐B inhibitors (IKK‐β) via extensive ligand‐based modeling and virtual screening
MA Al‐Sha'er, IS Almazari, MO Taha
Journal of Molecular Recognition 30 (6), e2604, 2017
22017
Discovery of Check Point Kinase1 (Chk1) Inhibitors as Potential Anticancer Agents Using Ligand-Based Modelling and Virtual Screening
MOT Mahmoud A.Al-Sha'er, Mohammad A. Khanfar
Journal of In Silico and In Vitro Pharmacology 1 (4), 1-11, 2015
2*2015
Evaluation of miscellaneous heat shock protein (Hsp90) inhibitors using different methodologies
MA Al-Sha’er
Der Pharma Chemical 5, 173-83, 2013
22013
Combination of pharmacophore modeling and 3D-QSAR analysis of potential glyoxalase-I inhibitors as anticancer agents
MA Al-Sha'er, QA Al-Balas, MA Hassan, GA Al Jabal, AM Almaaytah
Computational Biology and Chemistry 80, 102-110, 2019
12019
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