| Elaborate ligand-based modeling reveals new nanomolar heat shock protein 90α inhibitors MA Al-Sha’er, MO Taha Journal of chemical information and modeling 50 (9), 1706-1723, 2010 | 63 | 2010 |
| Discovery of novel CDK1 inhibitors by combining pharmacophore modeling, QSAR analysis and in silico screening followed by in vitro bioassay MA Al-Sha’er, MO Taha European Journal of Medicinal Chemistry 45 (9), 4316-4330, 2010 | 52 | 2010 |
| Application of docking-based comparative intermolecular contacts analysis to validate Hsp90α docking studies and subsequent in silico screening for inhibitors MA Al-Sha’er, MO Taha Journal of molecular modeling 18, 4843-4863, 2012 | 41 | 2012 |
| Discovery of novel urokinase plasminogen activator (uPA) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis MA Al-Sha’er, MA Khanfar, MO Taha Journal of molecular modeling 20, 1-15, 2014 | 32 | 2014 |
| Discovery of nanomolar phosphoinositide 3-kinase gamma (PI3Kγ) inhibitors using ligand-based modeling and virtual screening followed by in vitro analysis MO Taha, MA Al-Sha'er, MA Khanfar, AH Al-Nadaf European journal of medicinal chemistry 84, 454-465, 2014 | 31 | 2014 |
| Discovery of new heat shock protein 90 inhibitors using virtual co-crystallized pharmacophore generation MA Al-Sha'er, I Mansi, M Khanfar, A Abudayyh Journal of Enzyme Inhibition and Medicinal Chemistry 31 (sup4), 64-77, 2016 | 24 | 2016 |
| Combination of pharmacophore modeling and 3D-QSAR analysis of potential glyoxalase-I inhibitors as anticancer agents MA Al-Sha'er, QA Al-Balas, MA Hassan, GA Al Jabal, AM Almaaytah Computational Biology and Chemistry 80, 102-110, 2019 | 23 | 2019 |
| Discovery of new PKN2 inhibitory chemotypes via QSAR-guided selection of docking-based pharmacophores MA Al-Sha’er, HA Basheer, MO Taha Molecular Diversity 27 (1), 443-462, 2023 | 21 | 2023 |
| Evaluation of novel Akt1 inhibitors as anticancer agents using virtual co-crystallized pharmacophore generation MA Al-Sha’er, I Mansi, I Almazari, N Hakooz Journal of Molecular Graphics and Modelling 62, 213-225, 2015 | 21 | 2015 |
| Elaborate ligand-based modeling reveal new migration inhibitory factor inhibitors MA Al-Sha’er, S VanPatten, Y Al-Abed, MO Taha Journal of Molecular Graphics and Modelling 42, 104-114, 2013 | 20 | 2013 |
| Rational exploration of new pyridinium-based HSP90α inhibitors tailored to thiamine structure MA Al-Sha’er, MO Taha Medicinal Chemistry Research 21, 487-510, 2012 | 19 | 2012 |
| Design, synthesis, and biological evaluation of sulfonic acid ester and benzenesulfonamide derivatives as potential CETP inhibitors R Abu Khalaf, G Abu Sheikha, M Al-Sha’er, G Albadawi, M Taha Medicinal Chemistry Research 21, 3669-3680, 2012 | 16 | 2012 |
| Some sulfonamide drugs inhibit ATPase activity of heat shock protein 90: investigation by docking simulation and experimental validation GA Sheikha, MA Al-Sha’er, MO Taha Journal of Enzyme Inhibition and Medicinal Chemistry 26 (5), 603-609, 2011 | 14 | 2011 |
| Discovery of new phosphoinositide 3-kinase delta (PI3Kδ) inhibitors via virtual screening using crystallography-derived pharmacophore modelling and QSAR analysis MA Al-Sha'er, RA Al-Aqtash, MO Taha Medicinal Chemistry 15 (6), 588-601, 2019 | 13 | 2019 |
| Ligand-based modeling of Akt3 lead to potent dual Akt1/Akt3 inhibitor MA Al-Sha’er, MO Taha Journal of Molecular Graphics and Modelling 83, 153-166, 2018 | 11 | 2018 |
| Design, synthesis and biological evaluation of N4-sulfonamido-succinamic, phthalamic, acrylic and benzoyl acetic acid derivatives as potential DPP IV inhibitors RA Khalaf, GA Sheikha, M Al-Sha'er, M Taha The Open Medicinal Chemistry Journal 7, 39, 2013 | 11 | 2013 |
| Elaboration of novel TTK1 inhibitory leads via QSAR-guided selection of crystallographic pharmacophores followed by in vitro assay MA Al-Sha’er, MO Taha Current Computer-Aided Drug Design 17 (4), 511-522, 2021 | 10 | 2021 |
| Evaluation of antimicrobial activities of synthesized pyridinium derivatives MA Al-Sha'er Pharma Chem 6, 261-291, 2014 | 9 | 2014 |
| Novel sulfonamide–triazine hybrid derivatives: docking, synthesis, and biological evaluation as anticancer agents MA Alelaimat, MA Al-Sha’er, HA Basheer ACS omega 8 (15), 14247-14263, 2023 | 8 | 2023 |
| Investigation of binding characteristics of Phosphoinositide-dependent kinase-1 (PDK1) co-crystallized ligands through virtual pharmacophore modeling leading to novel anti-PDK1 … IA Mansi, MA Al-Sha'er, NM Mhaidat, MO Taha, R Shahin Medicinal Chemistry 16 (7), 860-880, 2020 | 7 | 2020 |
Mutasem TahaProfessor of Drug Design, University of JordanVerified email at ju.edu.jo
