| Genome-wide detection and characterization of positive selection in human populations PC Sabeti, P Varilly, B Fry, J Lohmueller, E Hostetter, C Cotsapas, X Xie, ... Nature 449 (7164), 913-918, 2007 | 2196 | 2007 |
| A haplotype map of the human genome D Altshuler Nature 437, 1299-1320, 2005 | 1187 | 2005 |
| Genome Sequence of the Streptomycin-Producing Microorganism Streptomyces griseus IFO 13350 Y Ohnishi, J Ishikawa, H Hara, H Suzuki, M Ikenoya, H Ikeda, ... Journal of bacteriology 190 (11), 4050-4060, 2008 | 676 | 2008 |
| A new pathway for polyketide synthesis in microorganisms N Funa, Y Ohnishi, I Fujii, M Shibuya, Y Ebizuka, S Horinouchi Nature 400 (6747), 897-899, 1999 | 407 | 1999 |
| Production of Plant-Specific Flavanones by Escherichia coli Containing an Artificial Gene Cluster EI Hwang, M Kaneko, Y Ohnishi, S Horinouchi Applied and environmental microbiology 69 (5), 2699-2706, 2003 | 309 | 2003 |
| The A‐factor regulatory cascade leading to streptomycin biosynthesis in Streptomyces griseus : identification of a target gene of the A‐factor receptor Y Ohnishi, S Kameyama, H Onaka, S Horinouchi Molecular microbiology 34 (1), 102-111, 1999 | 304 | 1999 |
| AdpA, a central transcriptional regulator in the A-factor regulatory cascade that leads to morphological development and secondary metabolism in Streptomyces griseus Y Ohnishi, H Yamazaki, JY Kato, A Tomono, S Horinouchi Bioscience, biotechnology, and biochemistry 69 (3), 431-439, 2005 | 292 | 2005 |
| Efficient production of (2S)-flavanones by Escherichia coli containing an artificial biosynthetic gene cluster I Miyahisa, M Kaneko, N Funa, H Kawasaki, H Kojima, Y Ohnishi, ... Applied microbiology and biotechnology 68, 498-504, 2005 | 225 | 2005 |
| Biosynthesis of γ-butyrolactone autoregulators that switch on secondary metabolism and morphological development in Streptomyces J Kato, N Funa, H Watanabe, Y Ohnishi, S Horinouchi Proceedings of the National Academy of Sciences 104 (7), 2378-2383, 2007 | 217 | 2007 |
| Combinatorial biosynthesis of flavones and flavonols in Escherichia coli I Miyahisa, N Funa, Y Ohnishi, S Martens, T Moriguchi, S Horinouchi Applied microbiology and biotechnology 71, 53-58, 2006 | 189 | 2006 |
| Determinants of protein thermostability observed in the 1.9-. ANG. crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus CA Kelly, M Nishiyama, Y Ohnishi, T Beppu, JJ Birktoft Biochemistry 32 (15), 3913-3922, 1993 | 177 | 1993 |
| An A-Factor-Dependent Extracytoplasmic Function Sigma Factor (ςAdsA) That Is Essential for Morphological Development in Streptomyces griseus H Yamazaki, Y Ohnishi, S Horinouchi Journal of bacteriology 182 (16), 4596-4605, 2000 | 131 | 2000 |
| AfsR recruits RNA polymerase to the afsS promoter: a model for transcriptional activation by SARPs A Tanaka, Y Takano, Y Ohnishi, S Horinouchi Journal of molecular biology 369 (2), 322-333, 2007 | 120 | 2007 |
| Properties and substrate specificity of RppA, a chalcone synthase-related polyketide synthase in Streptomyces griseus N Funa, Y Ohnishi, Y Ebizuka, S Horinouchi Journal of Biological Chemistry 277 (7), 4628-4635, 2002 | 117 | 2002 |
| Crystal structure of a γ-butyrolactone autoregulator receptor protein in Streptomyces coelicolor A3 (2) R Natsume, S Horinouchi, T Senda Foundations of Crystallography 60 (a1), 153-153, 2004 | 115 | 2004 |
| Genome-wide Distribution of AdpA, a Global Regulator for Secondary Metabolism and Morphological Differentiation in Streptomyces, Revealed the Extent and … A Higo, H Hara, S Horinouchi, Y Ohnishi DNA research 19 (3), 259-274, 2012 | 114 | 2012 |
| DNA‐binding specificity of AdpA, a transcriptional activator in the A‐factor regulatory cascade in Streptomyces griseus H Yamazaki, A Tomono, Y Ohnishi, S Horinouchi Molecular microbiology 53 (2), 555-572, 2004 | 114 | 2004 |
| Biosynthesis of Hexahydroxyperylenequinone Melanin via Oxidative Aryl Coupling by Cytochrome P-450 in Streptomyces griseus N Funa, M Funabashi, Y Ohnishi, S Horinouchi Journal of bacteriology 187 (23), 8149-8155, 2005 | 113 | 2005 |
| Heterologous production of flavanones in Escherichia coli: potential for combinatorial biosynthesis of flavonoids in bacteria M Kaneko, EI Hwang, Y Ohnishi, S Horinouchi Journal of Industrial Microbiology and Biotechnology 30, 456-461, 2003 | 105 | 2003 |
| Cinnamate:Coenzyme A Ligase from the Filamentous Bacterium Streptomyces coelicolor A3(2) M Kaneko, Y Ohnishi, S Horinouchi Journal of bacteriology 185 (1), 20-27, 2003 | 104 | 2003 |
