Lalima K. Madan (Formerly, Lalima G. Ahuja)
Cited by
Cited by
The crystal structure of a quercetin 2, 3-dioxygenase from Bacillus subtilis suggests modulation of enzyme activity by a change in the metal ion at the active site (s)
B Gopal, LL Madan, SF Betz, AA Kossiakoff
Biochemistry 44 (1), 193-201, 2005
Kinases and pseudokinases: lessons from RAF
AS Shaw, AP Kornev, J Hu, LG Ahuja, SS Taylor
Molecular and cellular biology 34 (9), 1538-1546, 2014
Kinase regulation by hydrophobic spine assembly in cancer
J Hu, LG Ahuja, HS Meharena, N Kannan, AP Kornev, SS Taylor, ...
Molecular and cellular biology 35 (1), 264-276, 2015
A dynamic hydrophobic core orchestrates allostery in protein kinases
J Kim, LG Ahuja, FA Chao, Y Xia, CL McClendon, AP Kornev, SS Taylor, ...
Science advances 3 (4), e1600663, 2017
Divalent Metal Ions Mg2+ and Ca2+ Have Distinct Effects on Protein Kinase A Activity and Regulation
MJ Knape, LG Ahuja, D Bertinetti, NCG Burghardt, B Zimmermann, ...
ACS chemical biology 10 (10), 2303-2315, 2015
Mutation of a kinase allosteric node uncouples dynamics linked to phosphotransfer
LG Ahuja, AP Kornev, CL McClendon, G Veglia, SS Taylor
Proceedings of the National Academy of Sciences 114 (6), E931-E940, 2017
Refolding and simultaneous purification by three‐phase partitioning of recombinant proteins from inclusion bodies
S Raghava, B Barua, PK Singh, M Das, L Madan, S Bhattacharyya, ...
Protein Science 17 (11), 1987-1997, 2008
Single turnover autophosphorylation cycle of the PKA RIIβ holoenzyme
P Zhang, MJ Knape, LG Ahuja, MM Keshwani, CC King, M Sastri, ...
PLoS biology 13 (7), e1002192, 2015
Tuning the “violin” of protein kinases: The role of dynamics‐based allostery
LG Ahuja, SS Taylor, AP Kornev
IUBMB life 71 (6), 685-696, 2019
Dynamic allostery-based molecular workings of kinase: peptide complexes
LG Ahuja, PC Aoto, AP Kornev, G Veglia, SS Taylor
Proceedings of the National Academy of Sciences 116 (30), 15052-15061, 2019
Globally correlated conformational entropy underlies positive and negative cooperativity in a kinase’s enzymatic cycle
Y Wang, M VS, J Kim, G Li, LG Ahuja, P Aoto, SS Taylor, G Veglia
Nature communications 10 (1), 1-11, 2019
Two PKA RIα holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP
TW Lu, J Wu, PC Aoto, JH Weng, LG Ahuja, N Sun, CY Cheng, P Zhang, ...
Proceedings of the National Academy of Sciences 116 (33), 16347-16356, 2019
Decoding the interactions regulating the active state mechanics of eukaryotic protein kinases
HS Meharena, X Fan, LG Ahuja, MM Keshwani, CL McClendon, AM Chen, ...
PLoS biology 14 (11), e2000127, 2016
Conformational basis for substrate recruitment in protein tyrosine phosphatase 10D
LL Madan, B Gopal
Biochemistry 50 (46), 10114-10125, 2011
Modulation of catalytic activity in multi-domain protein tyrosine phosphatases
LL Madan, S Veeranna, K Shameer, CCS Reddy, R Sowdhamini, B Gopal
PloS one 6 (9), e24766, 2011
PeptideMine-A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactomes
K Shameer, LL Madan, S Veeranna, B Gopal, R Sowdhamini
BMC bioinformatics 11 (1), 1-14, 2010
Addition of a polypeptide stretch at the N-terminus improves the expression, stability and solubility of recombinant protein tyrosine phosphatases from Drosophila melanogaster
LL Madan, B Gopal
Protein expression and purification 57 (2), 234-243, 2008
A catalytically disabled double mutant of Src tyrosine kinase can be stabilized into an active-like conformation
Y Meng, LG Ahuja, AP Kornev, SS Taylor, B Roux
Journal of molecular biology 430 (6), 881-889, 2018
Molecular Analysis of Aedes aegypti Classical Protein Tyrosine Phosphatases Uncovers an Ortholog of Mammalian PTP-1B Implicated in the Control of Egg …
DM Moretti, LG Ahuja, RD Nunes, CO Cudischevitch, CRO Daumas-Filho, ...
Plos one 9 (8), e104878, 2014
Bi-domain protein tyrosine phosphatases reveal an evolutionary adaptation to optimize signal transduction
LG Ahuja, B Gopal
Antioxidants & Redox Signaling 20 (14), 2141-2159, 2014
The system can't perform the operation now. Try again later.
Articles 1–20