The emergence of drug transporter-mediated multidrug resistance to cancer chemotherapy CP Wu, CH Hsieh, YS Wu Molecular pharmaceutics 8 (6), 1996-2011, 2011 | 264 | 2011 |
Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system DR Hwang, YS Wu, CW Chang, TW Lien, WC Chen, UK Tan, JTA Hsu, ... Bioorganic & medicinal chemistry 14 (1), 83-91, 2006 | 173 | 2006 |
Scaffold-hopping strategy: synthesis and biological evaluation of 5, 6-fused bicyclic heteroaromatics to identify orally bioavailable anticancer agents YS Tung, MS Coumar, YS Wu, HY Shiao, JY Chang, JP Liou, P Shukla, ... Journal of medicinal chemistry 54 (8), 3076-3080, 2011 | 102 | 2011 |
Synthesis and evaluation of 3-aroylindoles as anticancer agents: metabolite approach YS Wu, MS Coumar, JY Chang, HY Sun, FM Kuo, CC Kuo, YJ Chen, ... Journal of medicinal chemistry 52 (15), 4941-4945, 2009 | 101 | 2009 |
Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity YK Chiang, CC Kuo, YS Wu, CT Chen, MS Coumar, JS Wu, HP Hsieh, ... Journal of medicinal chemistry 52 (14), 4221-4233, 2009 | 71 | 2009 |
Antiviral drug discovery against SARS-CoV YS Wu, WH Lin, J T-A Hsu, HP Hsieh Current medicinal chemistry 13 (17), 2003-2020, 2006 | 56 | 2006 |
Sitravatinib sensitizes ABCB1-and ABCG2-overexpressing multidrug-resistant cancer cells to chemotherapeutic drugs CP Wu, SH Hsiao, YH Huang, LC Hung, YJ Yu, YT Chang, TH Hung, ... Cancers 12 (1), 195, 2020 | 35 | 2020 |
Human ATP-binding cassette transporter ABCG2 confers resistance to CUDC-907, a dual inhibitor of histone deacetylase and phosphatidylinositol 3-kinase CP Wu, YJ Hsieh, SH Hsiao, CY Su, YQ Li, YH Huang, CW Huang, ... Molecular pharmaceutics 13 (3), 784-794, 2016 | 34 | 2016 |
Alpha-mangostin reverses multidrug resistance by attenuating the function of the multidrug resistance-linked ABCG2 transporter CP Wu, SH Hsiao, M Murakami, YJ Lu, YQ Li, YH Huang, TH Hung, ... Molecular pharmaceutics 14 (8), 2805-2814, 2017 | 29 | 2017 |
Erdafitinib resensitizes ABCB1-overexpressing multidrug-resistant cancer cells to cytotoxic anticancer drugs CP Wu, TH Hung, SH Hsiao, YH Huang, LC Hung, YJ Yu, YT Chang, ... Cancers 12 (6), 1366, 2020 | 28 | 2020 |
Antihelminthic niclosamide modulates dendritic cells activation and function CS Wu, YR Li, JJW Chen, YC Chen, CL Chu, IH Pan, YS Wu, CC Lin Cellular immunology 288 (1-2), 15-23, 2014 | 28 | 2014 |
SIS3, a specific inhibitor of Smad3 reverses ABCB1-and ABCG2-mediated multidrug resistance in cancer cell lines CP Wu, M Murakami, SH Hsiao, TC Liu, N Yeh, YQ Li, TH Hung, YS Wu, ... Cancer letters 433, 259-272, 2018 | 21 | 2018 |
Tyrphostin RG14620 selectively reverses ABCG2-mediated multidrug resistance in cancer cell lines CP Wu, SH Hsiao, M Murakami, MJ Lu, YQ Li, CH Hsieh, SV Ambudkar, ... Cancer letters 409, 56-65, 2017 | 20 | 2017 |
Human ATP-binding cassette transporters ABCB1 and ABCG2 confer resistance to histone deacetylase 6 inhibitor ricolinostat (ACY-1215) in cancer cell lines CP Wu, YJ Hsieh, M Murakami, S Vahedi, SH Hsiao, N Yeh, AW Chou, ... Biochemical pharmacology 155, 316-325, 2018 | 17 | 2018 |
AC-93253 iodide, a novel Src inhibitor, suppresses NSCLC progression by modulating multiple Src-related signaling pathways YH Lai, SY Lin, YS Wu, HW Chen, JJW Chen Journal of Hematology & Oncology 10, 1-14, 2017 | 14 | 2017 |
Discovery of potent antimicrobial peptide analogs of Ixosin-B FDT Lung, KS Wang, ZJ Liao, SK Hsu, FY Song, CC Liou, YS Wu Bioorganic & medicinal chemistry letters 22 (12), 4185-4188, 2012 | 14 | 2012 |
Study of the inhibitory effects on TNF‐α‐induced NF‐κB activation of IMD 0354 analogs YR Li, CC Lin, CY Huang, YH Wong, CH Hsieh, HW Wu, JJW Chen, ... Chemical Biology & Drug Design 90 (6), 1307-1311, 2017 | 11 | 2017 |
Biotransformation of 6-methoxy-3-(3′, 4′, 5′-trimethoxy-benzoyl)-1H-indole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes HT Yao, YS Wu, YW Chang, HP Hsieh, WC Chen, SJ Lan, CT Chen, ... Drug metabolism and disposition 35 (7), 1042-1049, 2007 | 11 | 2007 |
P-glycoprotein mediates resistance to the anaplastic lymphoma kinase inhibitor ensartinib in cancer cells CP Wu, CY Hung, M Murakami, YS Wu, CL Lin, YH Huang, TH Hung, ... Cancers 14 (9), 2341, 2022 | 7 | 2022 |
3,5,2',4'-Tetramethoxystilbene, a fully methylated resveratrol analog, prevents platelet aggregation and thrombus formation by targeting the protease-activated receptor 4 pathway CCW Yi-Chun Chiang, Yu-Shan Wu, Ya-Fei Kang, Hui-Chun Wang, Meng-Chun Tsai Chemico-Biological Interactions, 109889, 2022 | 7 | 2022 |