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Wayne Yu
Wayne Yu
Ambrx, Inc.
Verified email at ambrx.com
Title
Cited by
Cited by
Year
ARX788, a site-specific anti-HER2 antibody–drug conjugate, demonstrates potent and selective activity in HER2-low and T-DM1–resistant breast and gastric cancers
L Skidmore, S Sakamuri, NA Knudsen, AG Hewet, S Milutinovic, ...
Molecular cancer therapeutics 19 (9), 1833-1843, 2020
1052020
Exploring the energy landscape of antibody− antigen complexes: protein dynamics, flexibility, and molecular recognition
MC Thielges, J Zimmermann, W Yu, M Oda, FE Romesberg
Biochemistry 47 (27), 7237-7247, 2008
772008
Crystal Structure of Botulinum Neurotoxin Type G Light Chain:  Serotype Divergence in Substrate Recognition,
JW Arndt, W Yu, F Bi, RC Stevens
Biochemistry 44 (28), 9574-9580, 2005
712005
Adaptive mutations alter antibody structure and dynamics during affinity maturation
R Adhikary, W Yu, M Oda, RC Walker, T Chen, RL Stanfield, IA Wilson, ...
Biochemistry 54 (11), 2085-2093, 2015
402015
Carbon− deuterium bonds as site-specific and nonperturbative probes for time-resolved studies of protein dynamics and folding
J Zimmermann, MC Thielges, W Yu, PE Dawson, FE Romesberg
The Journal of Physical Chemistry Letters 2 (5), 412-416, 2011
392011
Protein dynamics and the diversity of an antibody response
R Adhikary, W Yu, M Oda, J Zimmermann, FE Romesberg
Journal of Biological Chemistry 287 (32), 27139-27147, 2012
342012
Detection of high levels of recombination generated during PCR amplification of RNA templates
W Yu, KJ Rusterholtz, AT Krummel, N Lehman
Biotechniques 40 (4), 499-507, 2006
342006
Direct observation of structural heterogeneity in a β-sheet
ME Cremeens, J Zimmermann, W Yu, PE Dawson, FE Romesberg
Journal of the American Chemical Society 131 (16), 5726-5727, 2009
322009
Carbon–deuterium bonds as probes of protein thermal unfolding
W Yu, PE Dawson, J Zimmermann, FE Romesberg
The Journal of Physical Chemistry B 116 (22), 6397-6403, 2012
182012
Structure and dynamics of stacking interactions in an antibody binding site
R Adhikary, J Zimmermann, RL Stanfield, IA Wilson, W Yu, M Oda, ...
Biochemistry 58 (27), 2987-2995, 2019
52019
Analytical comparability to evaluate impact of manufacturing changes of ARX788, an Anti-HER2 ADC in late-stage clinical development
W Yu, MP Ramprasad, M Pal, C Chen, S Paruchuri, L Skidmore, ...
Plos one 18 (7), e0284198, 2023
22023
Protein dynamics and the evolution of novel protein function
J Zimmermann, MC Thielges, W Yu, FE Romesberg
Protein Engineering Handbook 1, 147-185, 2008
22008
Experimental Approaches Towards the Study of Protein Dynamics and Protein Folding
W Yu
The Scripps Research Institute, 2012
2012
Germline antecedents of an anti-HIV murine antibody
W Feng, J Zimmermann, W Yu, F Romesberg
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 58, 237-238, 2010
2010
Crystal structure of botulinum neurotoxin type G light chain
JW Arndt, W Yu, F Bi, RC Stevens
Foundations of Crystallography 61 (a1), 254-254, 2005
2005
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