ARX788, a site-specific anti-HER2 antibody–drug conjugate, demonstrates potent and selective activity in HER2-low and T-DM1–resistant breast and gastric cancers L Skidmore, S Sakamuri, NA Knudsen, AG Hewet, S Milutinovic, ... Molecular cancer therapeutics 19 (9), 1833-1843, 2020 | 105 | 2020 |
Exploring the energy landscape of antibody− antigen complexes: protein dynamics, flexibility, and molecular recognition MC Thielges, J Zimmermann, W Yu, M Oda, FE Romesberg Biochemistry 47 (27), 7237-7247, 2008 | 77 | 2008 |
Crystal Structure of Botulinum Neurotoxin Type G Light Chain: Serotype Divergence in Substrate Recognition, JW Arndt, W Yu, F Bi, RC Stevens Biochemistry 44 (28), 9574-9580, 2005 | 71 | 2005 |
Adaptive mutations alter antibody structure and dynamics during affinity maturation R Adhikary, W Yu, M Oda, RC Walker, T Chen, RL Stanfield, IA Wilson, ... Biochemistry 54 (11), 2085-2093, 2015 | 40 | 2015 |
Carbon− deuterium bonds as site-specific and nonperturbative probes for time-resolved studies of protein dynamics and folding J Zimmermann, MC Thielges, W Yu, PE Dawson, FE Romesberg The Journal of Physical Chemistry Letters 2 (5), 412-416, 2011 | 39 | 2011 |
Protein dynamics and the diversity of an antibody response R Adhikary, W Yu, M Oda, J Zimmermann, FE Romesberg Journal of Biological Chemistry 287 (32), 27139-27147, 2012 | 34 | 2012 |
Detection of high levels of recombination generated during PCR amplification of RNA templates W Yu, KJ Rusterholtz, AT Krummel, N Lehman Biotechniques 40 (4), 499-507, 2006 | 34 | 2006 |
Direct observation of structural heterogeneity in a β-sheet ME Cremeens, J Zimmermann, W Yu, PE Dawson, FE Romesberg Journal of the American Chemical Society 131 (16), 5726-5727, 2009 | 32 | 2009 |
Carbon–deuterium bonds as probes of protein thermal unfolding W Yu, PE Dawson, J Zimmermann, FE Romesberg The Journal of Physical Chemistry B 116 (22), 6397-6403, 2012 | 18 | 2012 |
Structure and dynamics of stacking interactions in an antibody binding site R Adhikary, J Zimmermann, RL Stanfield, IA Wilson, W Yu, M Oda, ... Biochemistry 58 (27), 2987-2995, 2019 | 5 | 2019 |
Analytical comparability to evaluate impact of manufacturing changes of ARX788, an Anti-HER2 ADC in late-stage clinical development W Yu, MP Ramprasad, M Pal, C Chen, S Paruchuri, L Skidmore, ... Plos one 18 (7), e0284198, 2023 | 2 | 2023 |
Protein dynamics and the evolution of novel protein function J Zimmermann, MC Thielges, W Yu, FE Romesberg Protein Engineering Handbook 1, 147-185, 2008 | 2 | 2008 |
Experimental Approaches Towards the Study of Protein Dynamics and Protein Folding W Yu The Scripps Research Institute, 2012 | | 2012 |
Germline antecedents of an anti-HIV murine antibody W Feng, J Zimmermann, W Yu, F Romesberg JOURNAL OF THE AMERICAN GERIATRICS SOCIETY 58, 237-238, 2010 | | 2010 |
Crystal structure of botulinum neurotoxin type G light chain JW Arndt, W Yu, F Bi, RC Stevens Foundations of Crystallography 61 (a1), 254-254, 2005 | | 2005 |